Development Level

Tbio 15 | 11,445
Tdark 7 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979

Disease

Carcinoma 18 | 11,493
group 3 medulloblastoma 13 | 4,104
medulloblastoma, large-cell 13 | 6,241
lung cancer 12 | 4,740
ovarian cancer 12 | 8,520
osteosarcoma 10 | 7,950
atypical teratoid / rhabdoid tumor 9 | 5,112
glioblastoma 8 | 5,792
Kidney cancer 7 | 2,613
primitive neuroectodermal tumor 7 | 3,035
adult high grade glioma 6 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
colon cancer 5 | 1,478
ependymoma 5 | 4,679
non-small cell lung cancer 5 | 2,890
Breast cancer 4 | 3,578
Multiple myeloma 4 | 1,332
dermatomyositis 4 | 966
invasive ductal carcinoma 4 | 2,951
malignant mesothelioma 4 | 3,232
Astrocytoma, Pilocytic 3 | 3,081
Liver cancer 3 | 604
Pick disease 3 | 1,894
astrocytic glioma 3 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
oligodendroglioma 3 | 2,850
Autosomal recessive predisposition 2 | 1,442
Galloway-Mowat syndrome 2 | 15
Leukemia 2 | 104
Leukemia, Myelocytic, Acute 2 | 120
NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE 2 | 4
Nephrotic syndrome, idiopathic, steroid-resistant 2 | 4
Rheumatoid arthritis 2 | 1,191
Waldenstrons macroglobulinemia 2 | 765
astrocytoma 2 | 1,146
ductal carcinoma in situ 2 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
nasopharyngeal carcinoma 2 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
psoriasis 2 | 6,694
tuberculosis 2 | 2,010
46 XX gonadal dysgenesis 1 | 5
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 1 | 21
Ampulla of Vater carcinoma 1 | 2
Autosomal recessive congenital ichthyosis 11 1 | 10
Chromosome 15q13.3 microdeletion syndrome 1 | 11
Decreased pain sensation 1 | 17
Deglutition Disorders 1 | 132
Delayed Puberty 1 | 97
Dilated ventricles (finding) 1 | 121
Dystonic disease 1 | 106
Familial atrial fibrillation 1 | 23
Gonadal Dysgenesis, 46,XX 1 | 5
Hyperinsulinism 1 | 133
Hyperkyphosis 1 | 111
Hyperopia 1 | 70
Hypogonadism, Isolated Hypogonadotropic 1 | 71
Hypogonadotropic hypogonadism 1 | 89
Hypoplastic feet 1 | 66
Hypoventilation 1 | 8
Infectious mononucleosis 1 | 14
Infertility 1 | 188
Irritable bowel syndrome 1 | 60
Isolated cases 1 | 72
Kyphosis deformity of spine 1 | 114
Leukemia, Acute Myeloid 1 | 17
Leukemia, Myeloid, Acute 1 | 105
Long narrow head 1 | 75
Lymphopenia 1 | 67
MYELODYSPLASTIC SYNDROME 1 | 53
Motor delay 1 | 147
Narrow cranium shape 1 | 75
Narrow forehead 1 | 34
Narrow head shape 1 | 75
Narrow skull shape 1 | 75
Neutropenia 1 | 72
No development of motor milestones 1 | 147
Nystagmus, continuous pendular 1 | 14
Obesity, Abdominal 1 | 24
Osteitis Deformans 1 | 11
Paget's disease of bone 1 | 36
Pendular Nystagmus 1 | 14
Plasmacytoma 1 | 7
Prader-Willi syndrome 1 | 48
Pure Gonadal Dysgenesis, 46, XX 1 | 5
Recurrent respiratory infections 1 | 141
Reduced fetal movement 1 | 51
Respiratory Depression 1 | 10
Short hands 1 | 50
Small hand 1 | 36
Specific learning disability 1 | 47
Striatonigral Degeneration, Infantile 1 | 4
Testicular cancer 1 | 25
Thin upper lip vermilion 1 | 67
Turridolichocephaly 1 | 75
Weight Gain 1 | 100
cystic fibrosis and chronic rhinosinusitis 1 | 214
interstitial lung disease 1 | 298
triple-A syndrome 1 | 17

Tissue

Endocrine System 20 | 18,159
Blood and immune system 18 | 16,909
Digestive Tract 18 | 17,369
Female tissues 18 | 17,400
Liver and Pancreas 18 | 16,750
Male tissues 18 | 17,142
Nervous System 18 | 16,725
Respiratory system 18 | 16,393
Skin and soft tissues 18 | 17,230
Urinary Tract 18 | 16,678
Cardiovascular System 17 | 15,192

Target Family

Non-IDG 21 | 12,091
Enzyme 1 | 4,145

GO Function

structural constituent of nucl... 22 | 22
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleoporin NDC1 NDC1 Tbio Non-IDG -0.66901 4.57 46
Nuclear pore complex protein Nup85 NUP85 Tbio Non-IDG -1.23703 17.9 139
Nuclear pore-associated protein 1 NPAP1 Tdark Non-IDG -0.73373 4.82 34
Putative nuclear envelope pore membrane protein POM 121B POM121B Tdark Non-IDG 0.27 0.57 0
Nuclear pore complex protein Nup98-Nup96 NUP98 Tbio Enzyme -2.26305 200.9 189
Transmembrane protein 33 TMEM33 Tbio Non-IDG -0.56358 3.95 53
Nuclear pore complex protein Nup214 NUP214 Tbio Non-IDG -2.25062 166.6 35
Nuclear pore complex protein Nup93 NUP93 Tbio Non-IDG -1.35565 22.2 62
Nuclear pore complex protein Nup205 NUP205 Tbio Non-IDG -0.62172 3.73 27
Nuclear pore complex protein Nup153 NUP153 Tbio Non-IDG -2.14396 129.9 100