Development Level

Tbio 19 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal seminal vesicle morph... 1 | 114
decreased lymphocyte cell numb... 1 | 83
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
enlarged uterus 1 | 11
increased blood uric acid leve... 1 | 5
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased granulocyte number 1 | 1
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

Cataract 18 | 297
Nuclear cataract 11 | 19
Nuclear non-senile cataract 11 | 18
CATARACT 16, MULTIPLE TYPES 10 | 15
Congenital Bilateral Cataracts 8 | 50
Congenital cataract 8 | 50
Lens Opacities 8 | 231
Blindness 7 | 88
Carcinoma 7 | 11,493
Myopia 7 | 176
Cataract microcornea syndrome 6 | 8
Cataract, Pulverulent 6 | 11
Cataract-microcornea syndrome 6 | 8
Corneal diameter decreased 6 | 47
Microcornea 6 | 47
cataract 2 multiple types 6 | 9
lung cancer 6 | 4,740
Autosomal recessive predisposition 5 | 1,442
Congenital total cataract 5 | 15
Presbyopia 5 | 20
CATARACT, ANTERIOR POLAR 4 | 6
Lens subluxation 4 | 12
ovarian cancer 4 | 8,520
pituitary cancer 4 | 1,972
CATARACT, AUTOSOMAL DOMINANT 3 | 4
Cataract, congenital, cerulean type 1 3 | 4
Cerebrotendinous xanthomatosis 3 | 13
atypical teratoid / rhabdoid tumor 3 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
malignant mesothelioma 3 | 3,232
psoriasis 3 | 6,694
subependymal giant cell astrocytoma 3 | 2,287
Alexander disease 2 | 11
Amblyopia 2 | 38
Autoimmune Diseases 2 | 67
CATARACT, COPPOCK-LIKE 2 | 2
Down syndrome 2 | 499
Hepatomegaly 2 | 285
Liver Cirrhosis, Experimental 2 | 769
Low Vision 2 | 174
Microphthalmia 2 | 76
Neurodegenerative Diseases 2 | 38
Neurodegenerative Disorders 2 | 79
Nystagmus 2 | 317
Prostatic Neoplasms 2 | 495
Uveitis 2 | 103
Visual Impairment 2 | 174
acute quadriplegic myopathy 2 | 1,158
adult high grade glioma 2 | 3,801
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
fibroadenoma 2 | 559
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
osteosarcoma 2 | 7,950
pancreatic cancer 2 | 2,398
primary pancreatic ductal adenocarcinoma 2 | 1,109
Acute coronary syndrome 1 | 39
Atypical autism 1 | 26
CATARACT 17, MULTIPLE TYPES 1 | 1
CATARACT 23 1 | 1
CATARACT 23, MULTIPLE TYPES 1 | 1
CATARACT 42 1 | 1
Cataract, Autosomal Dominant, Multiple Types 1 1 | 1
Cataract, Congenital Nuclear, Autosomal Recessive 3 1 | 1
Congenital lamellar cataract 1 | 2
Cryptosporidiosis 1 | 13
Cycloplegia 1 | 12
Diabetic retinopathy 1 | 56
EMG: myopathic abnormalities 1 | 22
Elevated heart rate 1 | 25
Familial isolated dilated cardiomyopathy 1 | 41
Foot dorsiflexor weakness 1 | 27
Foot-drop 1 | 27
Heart Diseases 1 | 43
Hemophagocytic lymphohistiocytosis 1 | 30
Hypopituitarism 1 | 40
Iris disease 1 | 10
Irritation - emotion 1 | 68
LEFT VENTRICULAR NONCOMPACTION 10 1 | 40
LEFT VENTRICULAR NONCOMPACTION 8 1 | 40
Late-onset proximal muscle weakness 1 | 2
Neurofibromatosis 1 | 40
Photosensitivity of skin 1 | 51
Rapidly progressive 1 | 27
Rapidly progressive disorder 1 | 27
Respiratory Distress Syndrome, Adult 1 | 40
Respiratory insufficiency due to muscle weakness 1 | 37
Synovial sarcoma 1 | 25
Weak cry 1 | 17

Tissue

Digestive Tract 18 | 17,369
Endocrine System 18 | 18,159
Nervous System 15 | 16,725
Blood and immune system 13 | 16,909
Male tissues 13 | 17,142
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Urinary Tract 12 | 16,678
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Cardiovascular System 8 | 15,192

Target Family

Non-IDG 19 | 12,091
Enzyme 1 | 4,145

GO Function

structural constituent of eye ... 20 | 20
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-crystallin A3 CRYBA1 Tbio Non-IDG -1.45158 27.2 133
Beta-crystallin B1 CRYBB1 Tbio Non-IDG -1.89050 77.2 109
Beta-crystallin A2 CRYBA2 Tdark Non-IDG -0.88890 7.28 38
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial CPOX Tbio Enzyme -2.05504 112.4 87
Beta-crystallin B2 CRYBB2 Tbio Non-IDG -2.07219 121.7 71
Gamma-crystallin A CRYGA Tbio Non-IDG -1.05783 10.00 17
Beta-crystallin S CRYGS Tbio Non-IDG -2.79704 615.6 150
Gamma-crystallin D CRYGD Tbio Non-IDG -2.86961 731.4 164
Gamma-crystallin B CRYGB Tbio Non-IDG -2.22103 154.0 55
Phakinin BFSP2 Tbio Non-IDG -2.51557 325.7 81