Development Level

Tdark 5 | 7,003
Tbio 3 | 10,625

IMPC Term

abnormal vibrissa morphology 1 | 17
improved glucose tolerance 1 | 56
preweaning lethality, incomple... 1 | 260

Disease

psoriasis 6 | 6,685
ovarian cancer 3 | 8,484
Atopic dermatitis 2 | 944
Breast cancer 2 | 3,094
Congenital ichthyosiform erythroderma 2 | 27
Epidermolytic hyperkeratosis 2 | 13
Ichthyosis vulgaris 2 | 15
Skin Neoplasms 2 | 49
Skin disease 2 | 65
Squamous cell carcinoma 2 | 94
osteosarcoma 2 | 7,933
periodontitis 2 | 269
Acanthoma 1 | 4
African histoplasmosis 1 | 1
Ainhum 1 | 5
Arsenic Poisoning 1 | 59
Cancer 1 | 2,346
Carcinoma 1 | 2,147
Congenital reticular ichthyosiform erythroderma 1 | 2
Contact Dermatitis 1 | 80
Ectodermal dysplasia/ skin fragility syndrome 1 | 1
Erythrokeratoderma, Reticular 1 | 1
Erythrokeratodermia variabilis 1 | 10
Filamentary keratitis 1 | 4
Hyperkeratosis, Epidermolytic 1 | 5
Ichthyosis, Cyclic, with Epidermolytic Hyperkeratosis 1 | 2
Keratosis 1 | 34
Liver carcinoma 1 | 217
Netherton syndrome 1 | 14
Obesity 1 | 616
Oculodentodigital dysplasia 1 | 14
Pachyonychia Congenita 1 | 9
Palmoplantar keratosis 1 | 36
Panic disorder 1 | 55
Syringoma 1 | 10
Vohwinkel Syndrome, Variant Form 1 | 1
X-linked ichthyosis 1 | 18
adult high grade glioma 1 | 2,148
cystic fibrosis 1 | 1,665
diabetes mellitus 1 | 1,663
esophageal adenocarcinoma 1 | 737
glioblastoma 1 | 5,572
interstitial cystitis 1 | 2,299
medulloblastoma, large-cell 1 | 6,234
non-inflammatory breast cancer 1 | 208
non-small cell lung cancer 1 | 2,798
spina bifida 1 | 1,064

Tissue

Cardiovascular System 8 | 17,958
Digestive Tract 8 | 18,473
Female tissues 8 | 18,647
Liver and Pancreas 8 | 18,136
Nervous System 8 | 18,561
Skin and soft tissues 8 | 18,115
Blood and immune system 7 | 17,995
Endocrine System 7 | 18,512
Male tissues 7 | 17,969
Respiratory system 7 | 17,484
Urinary Tract 7 | 18,444

Target Family

Non-IDG 8 | 11,971

GO Function

structural constituent of epid... 8 | 8
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Keratin, type I cytoskeletal 10 KRT10 Tbio Non-IDG -2.80444 621.7 603
Keratin, type I cuticular Ha6 KRT36 Tdark Non-IDG -0.23449 1.93 82
Keratin-associated protein 1-3 KRTAP1-3 Tdark Non-IDG -0.22185 1.78 46
Plakophilin-1 PKP1 Tbio Non-IDG -1.83552 73.8 91
Loricrin LOR Tbio Non-IDG -2.53836 343.8 40
Keratin-associated protein 5-8 KRTAP5-8 Tdark Non-IDG 0.00000 0
Keratin, type II cuticular Hb4 KRT84 Tdark Non-IDG -0.20829 1.67 40
Keratin, type II cuticular Hb2 KRT82 Tdark Non-IDG 0.79 0.15 70