Development Level

Tchem 6 | 1,598
Tbio 4 | 11,445

IMPC Phenotype

decreased prepulse inhibition 2 | 82
increased startle reflex 2 | 112
preweaning lethality, complete... 2 | 979
abnormal embryo size 1 | 220
abnormal forelimb morphology 1 | 2
abnormal gait 1 | 69
abnormal locomotor activation 1 | 16
abnormal response to new envir... 1 | 10
corneal vascularization 1 | 6
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating glycerol... 1 | 16
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased threshold for audito... 1 | 26
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
mammalian phenotype 1 | 17
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 8 | 11,493
Hypertension 6 | 396
Kidney cancer 5 | 2,613
glioblastoma 4 | 5,792
lung cancer 4 | 4,740
Hypertensive disease 3 | 292
atypical teratoid / rhabdoid tumor 3 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
psoriasis 3 | 6,694
Bipolar Disorder 2 | 666
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Pick disease 2 | 1,894
Stormorken syndrome 2 | 6
Tubular aggregate myopathy 2 | 3
adult high grade glioma 2 | 3,801
cystic fibrosis 2 | 1,696
ependymoma 2 | 4,679
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
medulloblastoma, large-cell 2 | 6,241
progressive supranuclear palsy 2 | 676
Adult onset 1 | 82
Alzheimer's disease 1 | 658
Amenorrhea Secondary to Ovarian Dysfunction 1 | 8
Anhidrosis 1 | 23
Atrophic vaginitis 1 | 14
Atrophy of cerebellum 1 | 103
Autosomal dominant cerebellar ataxia 1 | 33
Autosomal recessive Robinow syndrome 1 | 27
Bipolar I disorder 1 | 23
Cardiomegaly 1 | 116
Cerebellar degeneration 1 | 103
Chronic Kidney Diseases 1 | 13
Chronic obstructive pulmonary disease 1 | 184
Contraception 1 | 15
Corpus Luteum Insufficiency Syndrome 1 | 8
Disease Susceptibility 1 | 5
Duchenne muscular dystrophy 1 | 601
Dysfunctional uterine bleeding 1 | 9
Endometrial Hyperplasia Prevention 1 | 9
Endometrial cancer 1 | 311
Endometrial carcinoma 1 | 15
Endometriosis 1 | 540
Focal glomerulosclerosis 1 | 37
Gait, Unsteady 1 | 29
Glomerulosclerosis, Focal Segmental 1 | 28
Hypertrophy 1 | 17
Infertility Secondary to Progesterone Deficiency 1 | 8
Infratentorial atrophy 1 | 103
Kidney disease 1 | 430
Megalocornea 1 | 13
Menopausal flushing 1 | 17
Mental disorders 1 | 12
Myopathies, Structural, Congenital 1 | 15
Nephrotic Syndrome 1 | 78
Neurodegenerative disease 1 | 414
Photosensitive epilepsy 1 | 10
Polycystic kidney disease 1 1 | 21
Polycystic kidney disease 2 1 | 11
Postmenopausal osteoporosis 1 | 19
Prevention of Premature Labor 1 | 9
Progressive disorder 1 | 142
Progressive renal failure 1 | 13
Proteinuria 1 | 144
SPINOCEREBELLAR ATAXIA 41 1 | 1
Secondary malignant neoplasm of kidney 1 | 9
Secondary physiologic amenorrhea 1 | 32
Severe combined immunodeficiency 1 | 51
Sialolithiasis 1 | 2
Spinocerebellar Ataxias 1 | 34
Spinocerebellar ataxia type 14 1 | 1
Weight Gain 1 | 100
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
astrocytic glioma 1 | 2,597
atypical teratoid/rhabdoid tumor 1 | 357
breast carcinoma 1 | 1,638
chorea-acanthocytosis 1 | 12
colon cancer 1 | 1,478
cutaneous lupus erythematosus 1 | 1,057
facioscapulohumeral dystrophy 1 | 288
group 3 medulloblastoma 1 | 4,104
head and neck cancer 1 | 271
interstitial cystitis 1 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
invasive ductal carcinoma 1 | 2,951
lung adenocarcinoma 1 | 2,716
lung carcinoma 1 | 2,843
malignant mesothelioma 1 | 3,232
non primary Sjogren syndrome sicca 1 | 891
non-small cell lung cancer 1 | 2,890
oligodendroglioma 1 | 2,850
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
posterior fossa group B ependymoma 1 | 416
substance-related disorder 1 | 162
ulcerative colitis 1 | 1,819

Tissue

Urinary Tract 10 | 16,678
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Liver and Pancreas 9 | 16,750
Nervous System 9 | 16,725
Blood and immune system 8 | 16,909
Female tissues 8 | 17,400
Male tissues 8 | 17,142
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Cardiovascular System 7 | 15,192

Target Family

Ion Channel 7 | 344
Non-IDG 3 | 12,091

GO Function

store-operated calcium channel... 10 | 10
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Short transient receptor potential channel 7 TRPC7 Tchem Ion Channel -2.43775 199.8 220
Protein orai-3 ORAI3 Tbio Non-IDG -1.59146 36.6 211
Protein orai-2 ORAI2 Tbio Non-IDG -1.27446 13.1 113
Short transient receptor potential channel 1 TRPC1 Tbio Ion Channel -2.52589 340.7 162
Short transient receptor potential channel 6 TRPC6 Tchem Ion Channel -2.82303 661.6 320
Short transient receptor potential channel 3 TRPC3 Tchem Ion Channel -2.46704 294.6 217
Short transient receptor potential channel 5 TRPC5 Tchem Ion Channel -2.25002 172.0 220
Calcium release-activated calcium channel protein 1 ORAI1 Tchem Ion Channel -2.60545 389.7 360
Short transient receptor potential channel 4 TRPC4 Tchem Ion Channel -2.28183 190.1 229
Stromal interaction molecule 2 STIM2 Tbio Non-IDG -1.87544 70.2 212