Development Level

Tbio 11 | 11,445
Tchem 8 | 1,598
Tclin 4 | 613
Tdark 1 | 6,588

IMPC Phenotype

abnormal heart morphology 1 | 162
decreased circulating insulin ... 1 | 76
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
improved glucose tolerance 1 | 79
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 19 | 11,493
psoriasis 11 | 6,694
Cancer 9 | 2,499
Liver disease 7 | 237
Prostatic Neoplasms 7 | 495
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Chemical and Drug Induced Liver Injury 6 | 195
atypical teratoid / rhabdoid tumor 6 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
medulloblastoma, large-cell 6 | 6,241
Autosomal recessive predisposition 5 | 1,442
adult high grade glioma 5 | 3,801
diabetes mellitus 5 | 1,728
glioblastoma 5 | 5,792
group 3 medulloblastoma 5 | 4,104
lung cancer 5 | 4,740
non-small cell lung cancer 5 | 2,890
osteosarcoma 5 | 7,950
ovarian cancer 5 | 8,520
Astrocytoma, Pilocytic 4 | 3,081
Congenital adrenal hyperplasia 4 | 73
Epilepsy 4 | 792
adrenocortical carcinoma 4 | 1,428
ependymoma 4 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung carcinoma 4 | 2,843
oligodendroglioma 4 | 2,850
pancreatic cancer 4 | 2,398
Acute kidney injury 3 | 70
Adenocarcinoma 3 | 122
Adverse reaction to drug 3 | 61
Alcoholic Intoxication, Chronic 3 | 289
Alzheimer's disease 3 | 658
Atrial Fibrillation 3 | 124
Breast Neoplasms 3 | 445
Depressive disorder 3 | 409
Drug-Related Side Effects and Adverse Reactions 3 | 62
Hepatitis C 3 | 94
Major Depressive Disorder 3 | 301
Malaria 3 | 160
Mammary Neoplasms 3 | 425
Melanoma 3 | 711
Pick disease 3 | 1,894
Schizophrenia 3 | 1,160
Unipolar Depression 3 | 250
astrocytoma 3 | 1,146
cutaneous lupus erythematosus 3 | 1,057
ductal carcinoma in situ 3 | 1,745
lung adenocarcinoma 3 | 2,716
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819
Abnormality of blood and blood-forming tissues 2 | 10
Abnormality of metabolism/homeostasis 2 | 134
Abnormality of the haematopoietic system 2 | 10
Alzheimer Disease 2 | 83
Antley-Bixler syndrome 2 | 16
Bone Diseases, Metabolic 2 | 14
Breast cancer 2 | 3,578
Cholestasis 2 | 155
Coronary artery disease 2 | 268
Cushing's syndrome 2 | 48
Diarrhea 2 | 253
Dystonia 2 | 164
Fatty Liver 2 | 70
Growth delay 2 | 114
Growth failure 2 | 114
Growth retardation 2 | 115
Gynecomastia 2 | 64
Heart disease 2 | 306
Hematological Disease 2 | 18
Hyperandrogenism 2 | 34
Hypertension 2 | 396
Kidney Failure, Chronic 2 | 46
Kidney disease 2 | 430
Liver Cirrhosis 2 | 181
Lung Neoplasms 2 | 232
Mental Depression 2 | 333
Metabolic Bone Disorder 2 | 11
Nicotine dependence 2 | 54
Osteoporosis 2 | 363
Pain agnosia 2 | 104
Parkinson Disease 2 | 64
Polycystic ovary syndrome 2 | 360
Poor growth 2 | 114
Pseudohermaphroditism 2 | 16
Renal salt wasting 2 | 18
Skin cancer 2 | 469
Tremor 2 | 113
Very poor growth 2 | 114
active Crohn's disease 2 | 922
adrenocortical adenoma 2 | 131
aldosterone-producing adenoma 2 | 665
astrocytic glioma 2 | 2,597
chronic rhinosinusitis 2 | 512
gliosarcoma 2 | 18
nasopharyngeal carcinoma 2 | 1,058
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
substance-related disorder 2 | 162

Tissue

Endocrine System 20 | 18,159
Digestive Tract 19 | 17,369
Female tissues 19 | 17,400
Liver and Pancreas 19 | 16,750
Skin and soft tissues 19 | 17,230
Respiratory system 17 | 16,393
Urinary Tract 17 | 16,678
Blood and immune system 16 | 16,909
Male tissues 16 | 17,142
Nervous System 12 | 16,725
Cardiovascular System 9 | 15,192

Target Family

Non-IDG 15 | 12,091
Enzyme 9 | 4,145

GO Function

steroid hydroxylase activity 24 | 24
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cholesterol 25-hydroxylase CH25H Tbio Enzyme -1.54426 38.2 54
Cholesterol 24-hydroxylase CYP46A1 Tbio Enzyme -1.84856 68.6 197
Putative inactive cytochrome P450 2G1 CYP2G1P Tdark Non-IDG 0.00000 0
Cytochrome P450 2D6 CYP2D6 Tclin Enzyme -3.53105 3484.9 433
Cytochrome P450 11B2, mitochondrial CYP11B2 Tchem Non-IDG -2.82678 695.9 162
Vitamin D 25-hydroxylase CYP2R1 Tbio Enzyme -1.96830 95.4 152
Cytochrome P450 2C19 CYP2C19 Tchem Non-IDG -3.22652 1740.4 154
Putative cytochrome P450 2D7 CYP2D7 Tbio Non-IDG 0.00000 0
Cytochrome P450 2U1 CYP2U1 Tbio Non-IDG -1.28605 20.6 89
Cytochrome P450 2F1 CYP2F1 Tbio Non-IDG -1.53384 31.3 68