Development Level

Tbio 5 | 10,625

IMPC Phenotype

decreased mean corpuscular vol... 1 | 50
embryonic lethality prior to t... 1 | 187
preweaning lethality, complete... 1 | 633

Disease

ductal carcinoma in situ 4 | 1,745
invasive ductal carcinoma 4 | 2,950
malignant mesothelioma 4 | 3,163
medulloblastoma, large-cell 4 | 6,234
ovarian cancer 4 | 8,491
Breast cancer 3 | 3,098
Down syndrome 3 | 548
Pick disease 3 | 1,893
colon cancer 3 | 1,475
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
lung adenocarcinoma 3 | 2,714
non-small cell lung cancer 3 | 2,798
osteosarcoma 3 | 7,933
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
Atopic dermatitis 2 | 944
breast carcinoma 2 | 1,614
glioblastoma 2 | 5,572
group 4 medulloblastoma 2 | 1,875
interstitial cystitis 2 | 2,299
pancreatic cancer 2 | 2,300
pilocytic astrocytoma 2 | 3,086
posterior fossa group B ependymoma 2 | 1,530
psoriasis 2 | 6,685
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 1,563
Cardiovascular system disease 1 | 194
Coronary artery disease 1 | 240
Coronary heart disease 1 | 59
Disease Progression 1 | 125
Endometriosis 1 | 535
Eosinophilic esophagitis 1 | 31
IGA Glomerulonephritis 1 | 454
Lipid storage disease 1 | 7
Peripheral Neuropathy 1 | 303
Stomach Neoplasms 1 | 282
active Crohn's disease 1 | 918
acute quadriplegic myopathy 1 | 1,157
adrenocortical carcinoma 1 | 1,427
adult high grade glioma 1 | 2,148
aldosterone-producing adenoma 1 | 664
astrocytic glioma 1 | 2,241
astrocytoma 1 | 1,493
atypical teratoid / rhabdoid tumor 1 | 4,369
atypical teratoid/rhabdoid tumor 1 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 499
chronic lymphosyte leukemia 1 | 232
cutaneous lupus erythematosus 1 | 1,056
cystic fibrosis 1 | 1,670
dermatomyositis 1 | 966
ependymoma 1 | 2,514
esophageal adenocarcinoma 1 | 737
head and neck cancer and chronic obstructive pulmonary disease 1 | 237
lung cancer 1 | 4,473
medulloblastoma 1 | 1,524
mucosa-associated lymphoid tissue lymphoma 1 | 480
nephrosclerosis 1 | 329
oligodendroglioma 1 | 2,849
permanent atrial fibrillation 1 | 44
pituitary cancer 1 | 1,972
primary Sjogren syndrome 1 | 788
primary pancreatic ductal adenocarcinoma 1 | 1,271
primitive neuroectodermal tumor 1 | 3,031
sonic hedgehog group medulloblastoma 1 | 1,482
spina bifida 1 | 1,064
ulcerative colitis 1 | 2,087
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 5 | 17,994
Cardiovascular System 5 | 17,957
Digestive Tract 5 | 18,472
Endocrine System 5 | 18,511
Female tissues 5 | 18,646
Liver and Pancreas 5 | 18,135
Male tissues 5 | 17,968
Nervous System 5 | 18,560
Respiratory system 5 | 17,483
Skin and soft tissues 5 | 18,114
Urinary Tract 5 | 18,443

Target Family

Enzyme 5 | 4,146

GO Function

sphingosine-1-phosphate phosph... 5 | 5
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine-threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phospholipid phosphatase 2 PLPP2 Tbio Enzyme -1.33905 20.8 93
Sphingosine-1-phosphate phosphatase 1 SGPP1 Tbio Enzyme -0.82819 5.89 64
Phospholipid phosphatase 3 PLPP3 Tbio Enzyme -1.75974 61.0 81
Phospholipid phosphatase 1 PLPP1 Tbio Enzyme -1.42492 26.3 109
Sphingosine-1-phosphate phosphatase 2 SGPP2 Tbio Enzyme -0.61396 4.96 67