Development Level

Tbio 8 | 10,625
Tclin 2 | 602

IMPC Term

abnormal coat/hair pigmentatio... 1 | 54
abnormal iris transilluminatio... 1 | 1
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
decreased fasted circulating g... 1 | 49
decreased prepulse inhibition 1 | 52
decreased rib number 1 | 59
enlarged thymus 1 | 4
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased circulating sodium l... 1 | 71
increased grip strength 1 | 83
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260

Disease

glioblastoma 6 | 5,572
lung cancer 6 | 4,466
medulloblastoma, large-cell 6 | 6,234
osteosarcoma 5 | 7,933
ovarian cancer 5 | 8,484
atypical teratoid / rhabdoid tumor 4 | 4,369
pediatric high grade glioma 4 | 2,712
pituitary cancer 4 | 1,972
primitive neuroectodermal tumor 4 | 3,031
astrocytic glioma 3 | 2,241
ependymoma 3 | 2,514
subependymal giant cell astrocytoma 3 | 2,287
Brain Ischemia 2 | 87
Breast cancer 2 | 3,094
Oculocutaneous albinism 2 | 27
Status Epilepticus 2 | 85
adult high grade glioma 2 | 2,148
atypical teratoid/rhabdoid tumor 2 | 1,095
colon cancer 2 | 1,475
group 4 medulloblastoma 2 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
lung adenocarcinoma 2 | 2,713
lung carcinoma 2 | 2,844
medulloblastoma 2 | 1,524
non-small cell lung cancer 2 | 2,798
oligodendroglioma 2 | 2,849
pilocytic astrocytoma 2 | 3,086
posterior fossa group A ependymoma 2 | 1,511
sonic hedgehog group medulloblastoma 2 | 1,482
Administration of Corneal Anesthesia 1 | 6
Administration of Local Anesthetic Nerve Block 1 | 14
Administration of Regional Anesthesia 1 | 7
Adverse reaction to drug 1 | 54
Amelogenesis Imperfecta hypomaturation type 1 | 5
Amelogenesis imperfecta 1 | 26
Anesthesia for cesarean section 1 | 8
Bipolar disorder in remission 1 | 19
Burning mouth syndrome 1 | 5
Celiac disease 1 | 112
Chediak-Higashi syndrome 1 | 24
Chronic heart failure 1 | 46
Congestive heart failure 1 | 30
Conn's syndrome 1 | 22
Cough 1 | 21
Dysuria 1 | 24
Epilepsy characterized by intractable complex partial seizures 1 | 28
Hemorrhoids 1 | 13
Hermansky-Pudlak syndrome 1 | 43
Hyperaldosteronism 1 | 27
Hyperphosphatemia 1 | 32
Hypophosphatemia 1 | 31
Infestation by Phthirus pubis 1 | 7
Infestation by Sarcoptes scabiei var hominis 1 | 7
Itching of skin 1 | 19
Lennox-Gastaut syndrome 1 | 34
Life-Threatening Ventricular Tachycardia 1 | 15
Local Anesthesia for Endotracheal Intubation 1 | 6
Local Anesthesia for Ophthalmologic Procedure 1 | 7
Local Anesthesia for Urethral Pain 1 | 6
Local anesthesia 1 | 40
Local anesthesia, by infiltration 1 | 14
Local anesthetic intrathecal block 1 | 7
Localization-related epilepsy 1 | 13
Major Nerve Block for Surgery 1 | 8
Minor Skin Wound Pain 1 | 12
Motor cortex epilepsy 1 | 10
Mouth Irritation 1 | 12
Pain disorder 1 | 13
Parkinsonism 1 | 19
Partial Epilepsy Treatment Adjunct 1 | 16
Partial seizure 1 | 15
Pediculosis capitis 1 | 7
Poisoning by digitalis glycoside 1 | 8
Posterior polymorphous corneal dystrophy 1 | 24
Postherpetic neuralgia 1 | 12
Premature ejaculation 1 | 16
Prevent Minor Bacterial Skin Infection 1 | 10
Prevention of Seizures following Cranial Trauma or Surgery 1 | 7
Pruritus ani 1 | 14
Psychotic Disorders 1 | 20
Regional Anesthesia for Labor Pain 1 | 9
Regional Anesthesia for Ophthalmologic Surgery 1 | 6
Regional Anesthesia for Postoperative Pain 1 | 9
Regional Anesthesia for Surgery 1 | 9
Salivary Gland Neoplasms 1 | 45
Seizures in Neurosurgery 1 | 7
Simple partial seizure 1 | 26
Skin irritation 1 | 12
Sore throat symptom 1 | 12
Spasticity 1 | 26
Suppression of the Gag Reflex 1 | 12
Tinea Infections 1 | 10
Tinea corporis 1 | 25
Tonic-clonic epilepsy 1 | 47
Tonic-clonic seizure 1 | 11
Urethritis 1 | 10
Urinary Tract Irritation 1 | 24
Ventricular arrhythmia 1 | 14
facioscapulohumeral dystrophy 1 | 286
limb girdle muscular dystrophy 2B 1 | 74

Tissue

Blood and immune system 10 | 17,995
Cardiovascular System 10 | 17,958
Digestive Tract 10 | 18,473
Endocrine System 10 | 18,512
Female tissues 10 | 18,647
Liver and Pancreas 10 | 18,136
Male tissues 10 | 17,969
Nervous System 10 | 18,561
Respiratory system 10 | 17,484
Skin and soft tissues 10 | 18,115
Urinary Tract 10 | 18,444

Target Family

Transporter 7 | 473
Ion Channel 1 | 341
Kinase 1 | 634
Non-IDG 1 | 11,971

GO Function

sodium ion binding 10 | 10
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/potassium/calcium exchanger 5 SLC24A5 Tbio Transporter -1.58874 38.9 49
Sodium/potassium/calcium exchanger 3 SLC24A3 Tbio Transporter -1.00648 8.98 76
Sodium/potassium/calcium exchanger 2 SLC24A2 Tbio Transporter -1.20780 17.8 34
Sodium/potassium/calcium exchanger 4 SLC24A4 Tbio Transporter -1.19063 17.1 55
Sodium/potassium-transporting ATPase subunit alpha-1 ATP1A1 Tclin Transporter -1.56835 33.1 346
Pyridoxal kinase PDXK Tbio Kinase -2.44424 274.4 198
Sodium channel protein type 9 subunit alpha SCN9A Tclin Ion Channel -2.47810 311.9 283
Calpain-3 CAPN3 Tbio Non-IDG -2.44352 303.5 98
Sodium-dependent phosphate transport protein 2B SLC34A2 Tbio Transporter -1.90475 86.8 57
Sodium/potassium/calcium exchanger 1 SLC24A1 Tbio Transporter -1.76565 57.1 87