Development Level

Tbio 9 | 11,651
Tclin 2 | 612

IMPC Phenotype

abnormal coat-hair pigmentatio... 1 | 64
abnormal iris transilluminatio... 1 | 2
abnormal retina morphology 1 | 71
decreased fasted circulating g... 1 | 65
decreased prepulse inhibition 1 | 82
enlarged thymus 1 | 5
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 9 | 11,493
glioblastoma 7 | 5,792
lung cancer 7 | 4,740
medulloblastoma, large-cell 7 | 6,241
adult high grade glioma 6 | 3,801
atypical teratoid / rhabdoid tumor 6 | 5,112
osteosarcoma 6 | 7,950
ependymoma 5 | 4,679
ovarian cancer 5 | 8,520
primitive neuroectodermal tumor 5 | 3,035
Autosomal recessive predisposition 4 | 1,442
group 3 medulloblastoma 4 | 4,104
pituitary cancer 4 | 1,972
Breast cancer 3 | 3,578
Kidney cancer 3 | 2,613
astrocytic glioma 3 | 2,597
subependymal giant cell astrocytoma 3 | 2,287
Astrocytoma, Pilocytic 2 | 3,081
Multiple myeloma 2 | 1,332
Oculocutaneous albinism 2 | 29
Pick disease 2 | 1,894
Slow progression 2 | 89
Status Epilepticus 2 | 98
colon cancer 2 | 1,478
dermatomyositis 2 | 966
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
Abnormal cortical bone morphology 1 | 22
Abnormality of macular pigmentation 1 | 16
Abnormality of the ankles 1 | 5
Abnormality of the hip bone 1 | 16
Abnormality of the knee 1 | 6
Abnormality of the musculature 1 | 16
Achromatopsia 1 | 16
Acral ulceration leading to autoamputation of digits 1 | 3
Acro-Osteolysis 1 | 12
Adrenal cortical adenocarcinoma 1 | 4
Adrenal gland cancer 1 | 12
Amelogenesis Imperfecta hypomaturation type 1 | 7
Amelogenesis imperfecta 1 | 29
Anhidrosis 1 | 23
Anosmia 1 | 22
Blurred vision 1 | 19
Bradycardia 1 | 36
Celiac disease 1 | 116
Congenital stationary night blindness 1B 1 | 6
Cor pulmonale 1 | 6
Decreased pain sensation 1 | 17
Dystrophic fingernails 1 | 18
Dystrophic toenail changes 1 | 12
Elevated heart rate 1 | 25
Epileptic drop attack 1 | 11
Erythema 1 | 58
Eye pain 1 | 2
Febrile Convulsions 1 | 14
Focal Clonic Seizures 1 | 9
Foot acroosteolysis 1 | 5
Hereditary Motor and Sensory-Neuropathy Type II 1 | 4
Hereditary sensory and autonomic neuropathy type 2 1 | 4
Hereditary sensory neuropathy 1 | 11
Hyperekplexia 1 | 16
Hyperhidrosis, episodic 1 | 4
Hypogeusia 1 | 5
Hypoplasia of optic disc 1 | 12
Hypotonic seizures 1 | 11
Jaw pain 1 | 2
Lacrimation abnormality 1 | 4
Lordosis 1 | 54
Macular pigmentary changes 1 | 16
Miles-Carpenter syndrome 1 | 4
Muscle atrophy, proximal 1 | 11
Myalgia 1 | 54
NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IIA 1 | 4
Neonatal onset 1 | 21
Neuropathy, Hereditary Sensory and Autonomic, Type 2A 1 | 4
Pain 1 | 103
Palpitations 1 | 18
Paronychia Inflammation 1 | 9
Photosensitivity of skin 1 | 51
Podoconiosis 1 | 5
Pulmonary alveolar microlithiasis 1 | 4
Reduced visual acuity 1 | 63
Restrictive respiratory syndrome 1 | 3
Rosacea 1 | 25
Scapular weakness 1 | 23
Seizures, Focal 1 | 14
Sense of smell impaired 1 | 21
Severe myopia 1 | 22
Skin-Hair-Eye Pigmentation, Variation In, 4 1 | 1
Tonic - clonic seizures 1 | 44
Toxic diffuse goiter 1 | 2
Trigeminal Neuralgia 1 | 24
Winged scapula 1 | 23
Xerostomia 1 | 42
multidrug-resistant tuberculosis 1 | 7

Tissue

Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678
Blood and immune system 10 | 16,909
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Digestive Tract 9 | 17,369
Cardiovascular System 8 | 15,192

Target Family

Transporter 7 | 473
Enzyme 1 | 4,145
Ion Channel 1 | 344
Kinase 1 | 634
Non-IDG 1 | 12,091

GO Function

sodium ion binding 11 | 11
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/potassium/calcium exchanger 5 SLC24A5 Tbio Transporter -1.63611 43.9 61
Sodium/potassium/calcium exchanger 4 SLC24A4 Tbio Transporter -1.32054 20.8 63
G/T mismatch-specific thymine DNA glycosylase TDG Tbio Enzyme -2.46252 297.6 225
Sodium/potassium/calcium exchanger 3 SLC24A3 Tbio Transporter -1.12274 13.0 86
Sodium/potassium/calcium exchanger 2 SLC24A2 Tbio Transporter -1.39605 25.7 32
Sodium channel protein type 9 subunit alpha SCN9A Tclin Ion Channel -2.57994 379.2 327
Sodium/potassium-transporting ATPase subunit alpha-1 ATP1A1 Tclin Transporter -1.68777 43.2 399
Pyridoxal kinase PDXK Tbio Kinase -2.47099 287.1 218
Calpain-3 CAPN3 Tbio Non-IDG -2.45065 293.3 110
Sodium/potassium/calcium exchanger 1 SLC24A1 Tbio Transporter -1.90810 81.5 92