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Target Filters...

Development Level

Tbio 7 | 10,625
Tchem 1 | 1,890
Tdark 1 | 7,003

IMPC Phenotype

abnormal bone structure 1 | 131
abnormal incisor color 1 | 2
abnormal iris morphology 1 | 12
abnormal lens morphology 1 | 73
abnormal spine curvature 1 | 7
absent pinna reflex 1 | 21
cataract 1 | 26
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased fasted circulating g... 1 | 49
decreased lean body mass 1 | 195
decreased total body fat amoun... 1 | 186
eyelids fail to open 1 | 2
impaired glucose tolerance 1 | 52
increased circulating alkaline... 1 | 119
increased circulating magnesiu... 1 | 10
increased grip strength 1 | 83
kyphosis 1 | 5
preweaning lethality, incomple... 1 | 260

Disease

Hyperphosphatemia 5 | 32
Hypophosphatemia 5 | 31
atypical teratoid / rhabdoid tumor 4 | 4,369
glioblastoma 4 | 5,572
ovarian cancer 4 | 8,491
Pulmonary alveolar microlithiasis 3 | 5
adult high grade glioma 3 | 2,148
medulloblastoma, large-cell 3 | 6,234
nephrosclerosis 3 | 329
Basal ganglia calcification 2 | 17
Calcinosis 2 | 63
Fanconi syndrome 2 | 14
Gout 2 | 93
Hyperuricemia 2 | 35
Iron metabolism disease 2 | 17
Osteomalacia 2 | 28
Peripheral vascular disease 2 | 90
Rickets 2 | 42
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
non-small cell lung cancer 2 | 2,798
osteosarcoma 2 | 7,933
pancreatic cancer 2 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
psoriasis 2 | 6,685
ulcerative colitis 2 | 2,087
Adverse reaction to drug 1 | 54
Ankylosing spondylitis 1 | 138
Aortic valve calcification 1 | 3
Autosomal recessive infantile hypercalcemia 1 | 2
Barrett's esophagus 1 | 185
Basal Ganglia Calcification, Idiopathic, 1 1 | 5
Basal Ganglia Diseases 1 | 12
Bone Diseases, Developmental 1 | 25
Cardiovascular Diseases 1 | 50
Cardiovascular system disease 1 | 194
Choreatic disease 1 | 27
Chronic Kidney Diseases 1 | 22
Cor pulmonale 1 | 3
Dent disease 1 | 20
Dystonia 1 | 77
Endometriosis 1 | 535
FRTS1 1 | 2
Fahr's syndrome (disorder) 1 | 4
Fanconi renotubular syndrome 2 1 | 1
Glycogen storage disease 1 | 37
HYPOPHOSPHATEMIC RICKETS WITH HYPERCALCIURIA, HEREDITARY 1 | 1
Hereditary hypophosphatemic rickets with hypercalciuria 1 | 1
Hypercalcemia 1 | 37
Hypercalciuria 1 | 3
Hypochromic anemia 1 | 6
IGA Glomerulonephritis 1 | 454
Kidney disease 1 | 397
Liver Cirrhosis, Experimental 1 | 108
Multiple myeloma 1 | 1,327
Nephrocalcinosis 1 | 18
Nephrolithiasis 1 | 31
Nephrolithiasis-Osteoporosis, Hypophosphatemic, 1 1 | 1
Nephrolithiasis/osteoporosis, hypophosphatemic, 1 1 | 1
Pick disease 1 | 1,893
Primary hyperoxaluria 1 | 16
Rheumatoid Arthritis 1 | 1,170
Testicular Microlithiasis 1 | 1
URIC ACID CONCENTRATION, SERUM, QUANTITATIVE TRAIT LOCUS 4 1 | 1
active Crohn's disease 1 | 918
active ulcerative colitis 1 | 477
acute quadriplegic myopathy 1 | 1,157
astrocytic glioma 1 | 2,241
breast carcinoma 1 | 1,614
colon cancer 1 | 1,475
cutaneous lupus erythematosus 1 | 1,056
dermatomyositis 1 | 966
ductal carcinoma in situ 1 | 1,745
esophageal adenocarcinoma 1 | 737
facioscapulohumeral dystrophy 1 | 286
fibroadenoma 1 | 557
gastric carcinoma 1 | 832
group 4 medulloblastoma 1 | 1,875
hypophosphatemic nephrolithiasis/osteoporosis 1 1 | 1
interstitial cystitis 1 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,956
invasive ductal carcinoma 1 | 2,950
juvenile dermatomyositis 1 | 1,189
lingual-facial-buccal dyskinesia 1 | 10
lung cancer 1 | 4,473
lung carcinoma 1 | 2,844
non-small cell lung carcinoma 1 | 413
pituitary cancer 1 | 1,972
posterior fossa group B ependymoma 1 | 1,530
primary Sjogren syndrome 1 | 788
primary pancreatic ductal adenocarcinoma 1 | 1,271
primitive neuroectodermal tumor 1 | 3,031

Tissue

Blood and immune system 9 | 17,994
Cardiovascular System 9 | 17,957
Digestive Tract 9 | 18,472
Endocrine System 9 | 18,511
Female tissues 9 | 18,646
Liver and Pancreas 9 | 18,135
Nervous System 9 | 18,560
Skin and soft tissues 9 | 18,114
Urinary Tract 9 | 18,443
Male tissues 8 | 17,968
Respiratory system 8 | 17,483

Target Family

Transporter 9 | 473

GO Function

sodium:phosphate symporter act... 9 | 9
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine-threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium-dependent phosphate transport protein 2B SLC34A2 Tbio Transporter -2.02038 86.8 57
Sodium-dependent phosphate transport protein 2A SLC34A1 Tbio Transporter -1.95786 71.6 60
Sodium-dependent phosphate transport protein 4 SLC17A3 Tbio Transporter -1.09997 12.2 32
Sodium-dependent phosphate transporter 2 SLC20A2 Tbio Transporter -2.24481 165.3 97
Sodium-dependent phosphate transporter 1 SLC20A1 Tbio Transporter -1.76184 51.2 87
Sodium-dependent phosphate transport protein 3 SLC17A2 Tchem Transporter -0.17609 1.23 57
Sodium-dependent phosphate transport protein 2C SLC34A3 Tbio Transporter -1.67182 41.9 56
Sodium-dependent phosphate transport protein 1 SLC17A1 Tbio Transporter -1.72792 42.9 28
Probable small intestine urate exporter SLC17A4 Tdark Transporter -0.15550 1.39 31