Development Level

Tbio 8 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal gait 1 | 69
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased prepulse inhibition 1 | 82
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
small spleen 1 | 19

Disease

Carcinoma 9 | 11,493
Metabolic acidosis 5 | 90
Renal tubular acidosis 5 | 24
atypical teratoid / rhabdoid tumor 5 | 5,112
glioblastoma 5 | 5,792
medulloblastoma, large-cell 5 | 6,241
Kidney cancer 4 | 2,613
group 3 medulloblastoma 4 | 4,104
lung cancer 4 | 4,740
malignant mesothelioma 4 | 3,232
Hereditary elliptocytosis 3 | 22
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
ependymoma 3 | 4,679
invasive ductal carcinoma 3 | 2,951
ovarian cancer 3 | 8,520
psoriasis 3 | 6,694
Acidosis, Renal Tubular 2 | 2
Adenocarcinoma of lung 2 | 142
Alstrom syndrome 2 | 6
Alzheimer's disease 2 | 658
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Coronary artery disease 2 | 268
Disease Models, Animal 2 | 155
Exhibitionism 2 | 7
Intellectual disability 2 | 1,016
Transvestism 2 | 4
Varicose veins 2 | 20
Voyeurism 2 | 4
autosomal recessive nonsyndromic deafness 4 2 | 6
ductal carcinoma in situ 2 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung carcinoma 2 | 2,843
osteosarcoma 2 | 7,950
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Abnormality of metabolism/homeostasis 1 | 134
Anemia, Hemolytic 1 | 55
Autosomal recessive polycystic kidney disease 1 | 41
Band keratopathy 1 | 5
Brain disease 1 | 96
Cerebrovascular disease 1 | 238
Choledochal Cyst 1 | 9
Cognition Disorders 1 | 32
Congenital hemolytic anemia 1 | 32
Corneal Dystrophy, Band-Shaped 1 | 2
Corneal Opacity 1 | 53
Dementia 1 | 175
Developmental Disabilities 1 | 23
Elliptocytosis found 1 | 7
Elliptocytosis, Hereditary 1 | 9
Essential Hypertension 1 | 94
Gaucher disease type 3 1 | 67
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
Heart Diseases 1 | 43
Heart conduction disease 1 | 83
Heart disease 1 | 306
Hematologic Diseases 1 | 8
Hematological Disease 1 | 18
Hemolytic anemia 1 | 77
Hereditary spherocytosis 1 | 16
Hypertension 1 | 396
Hypocalcemia 1 | 32
Icterus 1 | 82
Increased bilirubin level (finding) 1 | 18
Increased calcium level in kidney 1 | 21
Increased red cell osmotic resistance 1 | 1
Intracranial hypertension 1 | 32
Liver Cirrhosis, Experimental 1 | 769
Liver cancer 1 | 604
Lung disease 1 | 142
Malaria 1 | 160
Melanoma 1 | 711
Metabolic acidosis, NAG, acidifying salts 1 | 1
Nephrocalcinosis 1 | 35
Obstructive sleep apnea 1 | 26
Osteomalacia 1 | 35
Osteopetrosis 1 | 43
Pathological fracture 1 | 20
Periodic hypokalemic paresis 1 | 7
Polycystic Kidney, Autosomal Recessive 1 | 9
Poor growth 1 | 114
Renal Tubular Acidosis, Proximal, With Ocular Abnormalities And Mental Retardation 1 | 1
Renal Tubular Acidosis, Type II 1 | 4
Renal bicarbonate wasting 1 | 1
Rickets 1 | 49
Short QT syndrome 1 | 12
Skin cancer 1 | 469
Usher syndrome 1 | 32
Very poor growth 1 | 114
active ulcerative colitis 1 | 764
cataract 14 multiple types 1 | 5
posterior fossa group A ependymoma 1 | 468
sarcoidosis 1 | 370

Tissue

Endocrine System 9 | 18,159
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Urinary Tract 9 | 16,678
Blood and immune system 8 | 16,909
Digestive Tract 8 | 17,369
Female tissues 8 | 17,400
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Cardiovascular System 7 | 15,192

Target Family

Transporter 9 | 473

GO Function

sodium:bicarbonate symporter a... 9 | 9
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Anion exchange protein 2 SLC4A2 Tbio Transporter -1.53800 24.1 77
Electrogenic sodium bicarbonate cotransporter 4 SLC4A5 Tbio Transporter -1.31656 21.0 30
Electrogenic sodium bicarbonate cotransporter 1 SLC4A4 Tbio Transporter -2.63743 436.2 124
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Anion exchange protein 4 SLC4A9 Tbio Transporter -1.76538 50.3 91
Band 3 anion transport protein SLC4A1 Tbio Transporter -3.23613 1628.1 165
Anion exchange protein 3 SLC4A3 Tdark Transporter -1.24579 12.7 20
Sodium-driven chloride bicarbonate exchanger SLC4A10 Tbio Transporter -1.39974 27.9 12
Electroneutral sodium bicarbonate exchanger 1 SLC4A8 Tbio Transporter -2.38877 237.2 116