Development Level

Tbio 17 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
increased fasted circulating g... 2 | 76
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
cataract 1 | 92
decreased circulating serum al... 1 | 82
decreased fasted circulating g... 1 | 65
decreased mean corpuscular vol... 1 | 79
hyperactivity 1 | 148
increased heart weight 1 | 62
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 15 | 11,493
osteosarcoma 12 | 7,950
ovarian cancer 10 | 8,520
non-small cell lung cancer 8 | 2,890
atypical teratoid / rhabdoid tumor 7 | 5,112
invasive ductal carcinoma 7 | 2,951
lung carcinoma 7 | 2,843
medulloblastoma, large-cell 7 | 6,241
psoriasis 7 | 6,694
subependymal giant cell astrocytoma 7 | 2,287
Breast cancer 6 | 3,578
Kidney cancer 6 | 2,613
ependymoma 6 | 4,679
Aarskog syndrome 5 | 12
adult high grade glioma 5 | 3,801
breast carcinoma 5 | 1,638
glioblastoma 5 | 5,792
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
malignant mesothelioma 5 | 3,232
Astrocytoma, Pilocytic 4 | 3,081
Dull intelligence 4 | 645
Intellectual disability 4 | 1,016
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Poor school performance 4 | 645
acute quadriplegic myopathy 4 | 1,158
astrocytic glioma 4 | 2,597
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
gastric carcinoma 4 | 807
lung adenocarcinoma 4 | 2,716
mucosa-associated lymphoid tissue lymphoma 4 | 484
pancreatic cancer 4 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
primitive neuroectodermal tumor 4 | 3,035
tuberculosis 4 | 2,010
Blepharoptosis 3 | 231
Broad flat nasal bridge 3 | 236
Cleft Palate 3 | 271
Cognitive delay 3 | 608
Cryptorchidism 3 | 296
Epilepsy 3 | 792
Failure to gain weight 3 | 365
Global developmental delay 3 | 608
Impaired cognition 3 | 96
Mental and motor retardation 3 | 608
Mental impairment 3 | 95
Nasal bridge wide 3 | 236
Orbital separation excessive 3 | 244
Pediatric failure to thrive 3 | 365
Pick disease 3 | 1,894
Seizures 3 | 596
Short stature 3 | 531
Strabismus 3 | 270
Uranostaphyloschisis 3 | 167
X- linked recessive 3 | 110
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
juvenile dermatomyositis 3 | 1,187
oligodendroglioma 3 | 2,850
ulcerative colitis 3 | 1,819
Abnormal behavior 2 | 52
Acquired scoliosis 2 | 281
Alzheimer's disease 2 | 658
Anteverted nostril 2 | 191
Attention deficit hyperactivity disorder 2 | 278
Byzanthine arch palate 2 | 194
Cancer 2 | 2,499
Clouding of corneal stroma 2 | 50
Concave bridge of nose 2 | 195
Congenital anomaly of face 2 | 56
Congenital clubfoot 2 | 109
Corneal Opacity 2 | 53
Curvature of spine 2 | 282
Decreased tendon reflex 2 | 122
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Electroencephalogram abnormal 2 | 101
Endometriosis 2 | 540
Frontal bossing 2 | 157
Hepatomegaly 2 | 285
Liver cancer 2 | 604
Low Vision 2 | 174
Neuropathy 2 | 261
Pectus excavatum 2 | 100
Short nose 2 | 132
Small nose 2 | 132
Type 2 diabetes mellitus 2 | 272
Visual Impairment 2 | 174
Waldenstrons macroglobulinemia 2 | 765
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
fibroadenoma 2 | 559
medulloblastoma 2 | 720
spina bifida 2 | 1,074

Tissue

Blood and immune system 20 | 16,909
Cardiovascular System 20 | 15,192
Digestive Tract 20 | 17,369
Endocrine System 20 | 18,159
Female tissues 20 | 17,400
Liver and Pancreas 20 | 16,750
Male tissues 20 | 17,142
Nervous System 20 | 16,725
Respiratory system 20 | 16,393
Skin and soft tissues 20 | 17,230
Urinary Tract 20 | 16,678

Target Family

Non-IDG 17 | 12,091
Enzyme 1 | 4,145
Kinase 1 | 634
Transporter 1 | 473

GO Function

small GTPase binding 20 | 20
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Peroxisomal targeting signal 1 receptor PEX5 Tbio Non-IDG -2.43126 272.8 138
ERBB receptor feedback inhibitor 1 ERRFI1 Tbio Non-IDG -1.86682 77.3 148
FYVE, RhoGEF and PH domain-containing protein 1 FGD1 Tbio Non-IDG -2.02545 109.7 42
FYVE, RhoGEF and PH domain-containing protein 3 FGD3 Tbio Non-IDG -0.92940 8.84 116
RILP-like protein 2 RILPL2 Tbio Non-IDG -0.86274 7.14 95
FYVE, RhoGEF and PH domain-containing protein 2 FGD2 Tbio Non-IDG 0.00000 51
RILP-like protein 1 RILPL1 Tbio Non-IDG -2.38230 232.7 84
PEX5-related protein PEX5L Tbio Non-IDG -1.58820 39.1 21
Protein RCC2 RCC2 Tbio Non-IDG -1.49831 31.4 148
E3 ubiquitin-protein ligase RNF152 RNF152 Tbio Enzyme -0.34321 1.96 2