Development Level

Tbio 27 | 10,625
Tchem 6 | 1,890
Tdark 4 | 7,003
Tclin 1 | 602

IMPC Term

preweaning lethality, complete... 3 | 633
decreased body weight 2 | 174
decreased lean body mass 2 | 195
increased startle reflex 2 | 38
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal tibia morphology 1 | 14
abnormal vocalization 1 | 21
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased circulating triglyce... 1 | 83
decreased prepulse inhibition 1 | 52
decreased total body fat amoun... 1 | 186
hyperactivity 1 | 108
increased bone mineral content 1 | 92
increased circulating alkaline... 1 | 119
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased circulating sodium l... 1 | 71
increased grip strength 1 | 83
increased lean body mass 1 | 107
preweaning lethality, incomple... 1 | 260

Disease

osteosarcoma 20 | 7,933
lung cancer 19 | 4,466
ovarian cancer 19 | 8,484
glioblastoma 17 | 5,572
psoriasis 17 | 6,685
medulloblastoma, large-cell 16 | 6,234
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
pediatric high grade glioma 9 | 2,712
pilocytic astrocytoma 9 | 3,086
Cancer 8 | 2,346
atypical teratoid / rhabdoid tumor 8 | 4,369
group 3 medulloblastoma 8 | 2,254
Influenza 7 | 142
dermatomyositis 7 | 933
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
juvenile dermatomyositis 7 | 1,189
lung carcinoma 7 | 2,844
pancreatic cancer 7 | 2,300
Breast cancer 6 | 3,094
astrocytic glioma 6 | 2,241
colon cancer 6 | 1,475
cutaneous lupus erythematosus 6 | 1,056
ependymoma 6 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
nasopharyngeal carcinoma 6 | 1,056
non-small cell lung cancer 6 | 2,798
posterior fossa group A ependymoma 6 | 1,511
primary Sjogren syndrome 6 | 789
primitive neuroectodermal tumor 6 | 3,031
systemic lupus erythematosus 6 | 156
ulcerative colitis 6 | 2,087
Multiple Sclerosis 5 | 498
active Crohn's disease 5 | 918
atypical teratoid/rhabdoid tumor 5 | 1,095
invasive ductal carcinoma 5 | 2,950
posterior fossa group B ependymoma 5 | 1,530
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis 5 | 1,557
Amyotrophic Lateral Sclerosis 4 | 431
Carcinoma 4 | 2,147
Multiple myeloma 4 | 1,327
Pick disease 4 | 1,893
Rheumatoid Arthritis 4 | 1,160
Waldenstrons macroglobulinemia 4 | 765
acute myeloid leukemia 4 | 780
ductal carcinoma in situ 4 | 1,745
group 4 medulloblastoma 4 | 1,875
hepatocellular carcinoma 4 | 532
lung adenocarcinoma 4 | 2,713
medulloblastoma 4 | 1,524
oligodendroglioma 4 | 2,849
pituitary cancer 4 | 1,972
Melanoma 3 | 261
acute quadriplegic myopathy 3 | 1,157
breast carcinoma 3 | 1,614
cystic fibrosis 3 | 1,665
diabetes mellitus 3 | 1,663
gastric cancer 3 | 430
nephrosclerosis 3 | 329
pancreatic carcinoma 3 | 567
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
primary pancreatic ductal adenocarcinoma 3 | 1,271
sonic hedgehog group medulloblastoma 3 | 1,482
spina bifida 3 | 1,064
tuberculosis and treatment for 6 months 3 | 686
Animal Mammary Neoplasms 2 | 136
Craniofacial Abnormalities 2 | 147
Dermatitis 2 | 107
Hepatitis C 2 | 90
Lupus erythematosus 2 | 80
Mammary Neoplasms, Experimental 2 | 150
Substance-Related Disorders 2 | 114
adult high grade glioma 2 | 2,148
aldosterone-producing adenoma 2 | 664
astrocytoma 2 | 1,493
chronic lymphosyte leukemia 2 | 232
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 557
hereditary spastic paraplegia 2 | 313
interstitial cystitis 2 | 2,299
malignant mesothelioma 2 | 3,162
mucosa-associated lymphoid tissue lymphoma 2 | 480
non primary Sjogren syndrome sicca 2 | 840
progressive supranuclear palsy 2 | 674
Alopecia 1 | 55
Blood pressure finding 1 | 56
Cleft Lip 1 | 91
Cleft palate 1 | 125
Disease of anatomical entity 1 | 25
Encephalitis 1 | 54
Fungal meningitis 1 | 7
Gout 1 | 93
Inflammation 1 | 109
Kidney Diseases 1 | 86
Neoplasm Metastasis 1 | 138
Squamous cell carcinoma of esophagus 1 | 82
Systemic arterial pressure 1 | 56
head and neck cancer and chronic obstructive pulmonary disease 1 | 237
limb girdle muscular dystrophy 2B 1 | 74
sarcoidosis 1 | 358

Tissue

Blood and immune system 37 | 17,995
Digestive Tract 37 | 18,473
Endocrine System 37 | 18,512
Female tissues 37 | 18,647
Male tissues 37 | 17,969
Nervous System 37 | 18,561
Skin and soft tissues 37 | 18,115
Urinary Tract 37 | 18,444
Cardiovascular System 36 | 17,958
Liver and Pancreas 36 | 18,136
Respiratory system 35 | 17,484

Target Family

Non-IDG 22 | 11,971
Enzyme 11 | 4,146
Epigenetic 4 | 242
Transcription Factor 1 | 1,400

GO Function

single-stranded RNA binding 38 | 38
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
mRNA decay activator protein ZFP36 ZFP36 Tbio Non-IDG -2.38153 220.3 0
DNA-directed RNA polymerase II subunit RPB7 POLR2G Tbio Enzyme -1.74939 59.4 153
Toll-like receptor 7 TLR7 Tclin Non-IDG -2.92878 974.2 670
Spermatid perinuclear RNA-binding protein STRBP Tdark Non-IDG -1.82506 66.9 35
Endoribonuclease LACTB2 LACTB2 Tbio Enzyme -0.15635 1.90 96
Protein LSM14 homolog A LSM14A Tbio Non-IDG -1.08621 15.6 103
Chromobox protein homolog 7 CBX7 Tchem Epigenetic -1.28247 24.5 70
RNA-binding protein 7 RBM7 Tbio Non-IDG -0.67056 6.57 67
Heterogeneous nuclear ribonucleoprotein F HNRNPF Tbio Non-IDG -1.54056 35.1 191
Interferon-induced helicase C domain-containing protein 1 IFIH1 Tbio Enzyme -2.56403 384.3 296