Development Level

Tbio 64 | 10,625
Tdark 9 | 7,003
Tchem 8 | 1,890

IMPC Term

preweaning lethality, complete... 6 | 633
embryonic lethality prior to t... 2 | 187
increased startle reflex 2 | 38
abnormal embryo size 1 | 112
abnormal foot plate morphology 1 | 2
abnormal heart morphology 1 | 51
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal vertebrae morphology 1 | 14
craniofacial phenotype 1 | 9
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased circulating alanine ... 1 | 53
decreased circulating chloride... 1 | 32
decreased circulating glycerol... 1 | 19
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased prepulse inhibition 1 | 52
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
enlarged heart 1 | 111
hydrops fetalis 1 | 22
increased bone mineral content 1 | 92
increased circulating triglyce... 1 | 24
increased grip strength 1 | 83
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased prepulse inhibition 1 | 21
short tibia 1 | 82
small heart 1 | 8
tremors 1 | 34

Disease

ovarian cancer 51 | 8,484
osteosarcoma 41 | 7,933
medulloblastoma, large-cell 35 | 6,234
lung cancer 33 | 4,466
psoriasis 31 | 6,685
Breast cancer 29 | 3,094
glioblastoma 28 | 5,572
Cancer 26 | 2,346
malignant mesothelioma 22 | 3,162
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,289
atypical teratoid / rhabdoid tumor 19 | 4,369
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,988
primitive neuroectodermal tumor 17 | 3,031
group 3 medulloblastoma 15 | 2,254
lung adenocarcinoma 15 | 2,713
Multiple myeloma 14 | 1,327
Waldenstrons macroglobulinemia 13 | 765
invasive ductal carcinoma 13 | 2,950
non-small cell lung cancer 13 | 2,798
pediatric high grade glioma 13 | 2,712
sonic hedgehog group medulloblastoma 12 | 1,482
oligodendroglioma 11 | 2,849
Fanconi's anemia 10 | 50
Pick disease 10 | 1,893
Xeroderma pigmentosum 10 | 41
colon cancer 10 | 1,475
nasopharyngeal carcinoma 10 | 1,056
pancreatic cancer 10 | 2,300
acute quadriplegic myopathy 9 | 1,157
adult high grade glioma 9 | 2,148
dermatomyositis 9 | 933
tuberculosis and treatment for 6 months 9 | 686
Cockayne syndrome 8 | 54
Mammary Neoplasms 8 | 410
atypical teratoid/rhabdoid tumor 8 | 1,095
breast carcinoma 8 | 1,614
ductal carcinoma in situ 8 | 1,745
subependymal giant cell astrocytoma 8 | 2,287
Neurodegenerative disease 7 | 383
adrenocortical carcinoma 7 | 1,427
astrocytic glioma 7 | 2,241
ependymoma 7 | 2,514
pilocytic astrocytoma 7 | 3,086
posterior fossa group A ependymoma 7 | 1,511
Lynch syndrome 6 | 33
astrocytoma 6 | 1,493
diabetes mellitus 6 | 1,663
group 4 medulloblastoma 6 | 1,875
juvenile dermatomyositis 6 | 1,189
lung carcinoma 6 | 2,844
pituitary cancer 6 | 1,972
primary Sjogren syndrome 6 | 789
progressive supranuclear palsy 6 | 674
Endometriosis 5 | 535
Peripheral Neuropathy 5 | 303
Photosensitive trichothiodystrophy 5 | 24
hepatocellular carcinoma 5 | 532
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
medulloblastoma 5 | 1,524
non primary Sjogren syndrome sicca 5 | 840
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
primary pancreatic ductal adenocarcinoma 5 | 1,271
tuberculosis 5 | 1,557
ulcerative colitis 5 | 2,087
Adenocarcinoma of lung (disorder) 4 | 48
Adenoma 4 | 165
Amyotrophic Lateral Sclerosis 4 | 431
Carcinoma 4 | 2,147
Familial adenomatous polyposis 4 | 31
Hereditary Breast and Ovarian Cancer Syndrome 4 | 14
Intellectual disability 4 | 573
Neoplasm Metastasis 4 | 138
Neoplastic Syndromes, Hereditary 4 | 48
Prostatic Neoplasms 4 | 471
Rothmund-Thomson syndrome 4 | 22
Stomach Neoplasms 4 | 282
esophageal adenocarcinoma 4 | 737
hereditary spastic paraplegia 4 | 313
pancreatic carcinoma 4 | 567
posterior fossa group B ependymoma 4 | 1,530
spina bifida 4 | 1,064
tuberculosis and treatment for 3 months 4 | 327
Arsenic Poisoning 3 | 59
Duchenne muscular dystrophy 3 | 602
IGA Glomerulonephritis 3 | 454
Malignant neoplasm of breast 3 | 63
Mammary Neoplasms, Experimental 3 | 150
Neoplasm Invasiveness 3 | 127
Prostate cancer 3 | 172
Rheumatoid Arthritis 3 | 1,160
Sebaceous adenoma 3 | 11
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
cutaneous lupus erythematosus 3 | 1,056
cystic fibrosis 3 | 1,665
gastric carcinoma 3 | 832
glioblastoma multiforme 3 | 347
inflammatory breast cancer 3 | 404
interstitial lung disease 3 | 291
non-small cell lung carcinoma 3 | 413
ovarian neoplasm 3 | 97

Tissue

Blood and immune system 75 | 17,995
Digestive Tract 75 | 18,473
Endocrine System 75 | 18,512
Female tissues 75 | 18,647
Male tissues 75 | 17,969
Nervous System 75 | 18,561
Skin and soft tissues 75 | 18,115
Urinary Tract 75 | 18,444
Cardiovascular System 74 | 17,958
Liver and Pancreas 74 | 18,136
Respiratory system 74 | 17,484

Target Family

Non-IDG 54 | 11,971
Enzyme 17 | 4,146
Transcription Factor 8 | 1,400
Epigenetic 1 | 242
Kinase 1 | 634

GO Function

single-stranded DNA binding 81 | 81
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Replication protein A 32 kDa subunit RPA2 Tbio Non-IDG -1.76828 59.7 468
DNA-directed RNA polymerase II subunit RPB7 POLR2G Tbio Enzyme -1.74939 59.4 153
CST complex subunit CTC1 CTC1 Tbio Non-IDG -1.61677 49.3 42
DNA-binding protein SMUBP-2 IGHMBP2 Tbio Non-IDG -1.84895 75.2 35
Cryptochrome-2 CRY2 Tbio Non-IDG -2.33124 215.9 131
F-box DNA helicase 1 FBXO18 Tbio Enzyme -1.11780 16.1 78
Replication protein A 14 kDa subunit RPA3 Tbio Non-IDG -1.80635 59.3 127
Transcriptional activator protein Pur-alpha PURA Tbio Non-IDG -2.13635 153.6 155
DNA repair protein complementing XP-C cells XPC Tbio Non-IDG -2.19755 151.0 193
Nucleoside diphosphate kinase A NME1 Tbio Kinase -2.87702 843.2 611