Development Level

Tbio 8 | 11,445

IMPC Phenotype

abnormal coat- hair morphology 1 | 19
abnormal spleen morphology 1 | 55
decreased circulating insulin ... 1 | 76
improved glucose tolerance 1 | 79
increased circulating alkaline... 1 | 122
long tibia 1 | 25

Disease

Breast cancer 5 | 3,578
Carcinoma 5 | 11,493
osteosarcoma 5 | 7,950
psoriasis 5 | 6,694
atypical teratoid / rhabdoid tumor 4 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung cancer 4 | 4,740
ovarian cancer 4 | 8,520
Astrocytoma, Pilocytic 3 | 3,081
Myocardial Infarction 3 | 151
cystic fibrosis 3 | 1,696
diabetes mellitus 3 | 1,728
glioblastoma 3 | 5,792
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
medulloblastoma, large-cell 3 | 6,241
oligodendroglioma 3 | 2,850
primitive neuroectodermal tumor 3 | 3,035
Alcoholic Intoxication, Chronic 2 | 289
Attention deficit hyperactivity disorder 2 | 278
Autistic Disorder 2 | 364
Cancer 2 | 2,499
Hypertensive disease 2 | 292
Increase in blood pressure 2 | 119
Obesity 2 | 678
Rheumatoid arthritis 2 | 1,191
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
ependymoma 2 | 4,679
gastric carcinoma 2 | 807
group 3 medulloblastoma 2 | 4,104
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
spina bifida 2 | 1,074
Abnormality of the skeletal system 1 | 11
Acrocyanosis 1 | 7
Amaurosis Fugax 1 | 8
Aortic aneurysm 1 | 38
Arachnodactyly 1 | 49
Arterial thrombosis 1 | 9
Autism Spectrum Disorders 1 | 75
Autistic behavior 1 | 20
Bleeding time prolonged 1 | 31
Brain hemorrhage 1 | 14
Carcinoma, Squamous Cell 1 | 110
Celiac disease 1 | 116
Cerebral Hemorrhage 1 | 42
Chronic Kidney Diseases 1 | 13
Common variable immunodeficiency 1 | 101
Convex nasal bridge 1 | 57
Coronary Arteriosclerosis 1 | 6
Diabetes Mellitus, Insulin-Dependent 1 | 48
Dyspnea 1 | 76
Dyspnea on exertion 1 | 24
Familial hypercholesterolemia - homozygous 1 | 7
Familial hyperlipidemia 1 | 6
Florid red complexion (finding) 1 | 3
Hallucinations 1 | 34
Hematocrit increased 1 | 5
Hemoglobin increased 1 | 6
Hypercholesterolemia, Familial 1 | 23
Hyperinsulinism 1 | 133
Hyperlipidemia 1 | 43
Hyperphagia 1 | 23
Hyperuricemia 1 | 49
Hypotrophic malar bone 1 | 129
Impaired left ventricular function 1 | 16
Impaired platelet aggregation 1 | 8
Increased appetite (finding) 1 | 23
Increased megakaryocyte count 1 | 6
Increased number of platelets 1 | 14
Increased red blood cell mass 1 | 4
Juvenile Myelomonocytic Leukemia 1 | 21
Kluver-Bucy syndrome 1 | 6
Language Disorders 1 | 13
Left-Sided Heart Failure 1 | 16
Leukemia, Myelomonocytic, Juvenile 1 | 20
Low anterior hairline 1 | 30
Lupus Erythematosus, Systemic 1 | 67
Malar flattening 1 | 129
Peripheral thrombosis 1 | 3
Plaque build-up in arteries supplying blood to heart 1 | 6
Platelet morphology abnormal 1 | 9
Primary Myelofibrosis 1 | 5
Progressive renal failure 1 | 13
Prominent nasal bridge 1 | 57
Renal Artery Stenosis 1 | 9
Retinitis pigmentosa 24 1 | 15
Scrapie 1 | 17
Serum cholesterol raised 1 | 22
Sitosterolemia 1 | 9
Somatic mutation 1 | 61
Squamous cell carcinoma 1 | 129
Steatohepatitis 1 | 44
Sudden Cardiac Death 1 | 29
Transient Cerebral Ischemia 1 | 25
Type 1 diabetes mellitus 1 | 109
Vesico-Ureteral Reflux 1 | 33
Vitiligo 1 | 73
interstitial lung disease 1 | 298

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Non-IDG 8 | 12,091

GO Function

signaling adaptor activity 8 | 8
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MAGUK p55 subfamily member 7 MPP7 Tbio Non-IDG 0.24 1.34 71
Receptor of activated protein C kinase 1 RACK1 Tbio Non-IDG -2.60480 437.9 300
Homer protein homolog 1 HOMER1 Tbio Non-IDG -2.45026 285.7 241
SH2B adapter protein 3 SH2B3 Tbio Non-IDG -2.51914 340.6 151
Actin filament-associated protein 1-like 2 AFAP1L2 Tbio Non-IDG -1.14059 20.5 91
Disabled homolog 2-interacting protein DAB2IP Tbio Non-IDG -1.69193 60.3 59
SH2B adapter protein 1 SH2B1 Tbio Non-IDG -1.79968 66.7 227
Low density lipoprotein receptor adapter protein 1 LDLRAP1 Tbio Non-IDG -2.44381 269.9 357