Development Level

Tbio 24 | 11,445
Tchem 6 | 1,598
Tclin 4 | 613
Tdark 1 | 6,588

IMPC Phenotype

decreased lean body mass 1 | 135
decreased mature B cell number 1 | 7
decreased mean corpuscular vol... 1 | 79
hypoactivity 1 | 132
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 25 | 11,493
ovarian cancer 22 | 8,520
glioblastoma 21 | 5,792
osteosarcoma 20 | 7,950
medulloblastoma, large-cell 18 | 6,241
psoriasis 18 | 6,694
adult high grade glioma 16 | 3,801
atypical teratoid / rhabdoid tumor 14 | 5,112
lung cancer 14 | 4,740
Cancer 13 | 2,499
astrocytic glioma 13 | 2,597
ependymoma 12 | 4,679
oligodendroglioma 12 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
malignant mesothelioma 11 | 3,232
group 3 medulloblastoma 10 | 4,104
lung carcinoma 10 | 2,843
Astrocytoma, Pilocytic 9 | 3,081
interstitial cystitis 9 | 2,312
subependymal giant cell astrocytoma 9 | 2,287
tuberculosis 9 | 2,010
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
lung adenocarcinoma 8 | 2,716
pancreatic cancer 8 | 2,398
primitive neuroectodermal tumor 8 | 3,035
Breast cancer 7 | 3,578
Kidney cancer 7 | 2,613
cystic fibrosis 7 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
juvenile dermatomyositis 7 | 1,187
non-small cell lung cancer 7 | 2,890
Autosomal recessive predisposition 6 | 1,442
Schizophrenia 6 | 1,160
colon cancer 6 | 1,478
group 4 medulloblastoma 6 | 1,855
invasive ductal carcinoma 6 | 2,951
pituitary cancer 6 | 1,972
Asthma 5 | 385
Bipolar Disorder 5 | 666
acute quadriplegic myopathy 5 | 1,158
cutaneous lupus erythematosus 5 | 1,057
Allergic hypersensitivity disease 4 | 126
Atopic dermatitis 4 | 952
Duchenne muscular dystrophy 4 | 601
Pick disease 4 | 1,894
Rheumatoid arthritis 4 | 1,191
active Crohn's disease 4 | 922
active ulcerative colitis 4 | 764
adrenocortical carcinoma 4 | 1,428
breast carcinoma 4 | 1,638
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
primary Sjogren syndrome 4 | 735
spina bifida 4 | 1,074
ulcerative colitis 4 | 1,819
Allergic rhinitis 3 | 94
Amyotrophic lateral sclerosis 3 | 451
Depressive disorder 3 | 409
Glaucoma 3 | 239
Liver Cirrhosis, Experimental 3 | 769
Mental Depression 3 | 333
Parkinson's disease 3 | 392
acute myeloid leukemia 3 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
limb girdle muscular dystrophy 2A 3 | 213
mucosa-associated lymphoid tissue lymphoma 3 | 484
non primary Sjogren syndrome sicca 3 | 891
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
posterior fossa group A ependymoma 3 | 468
primary pancreatic ductal adenocarcinoma 3 | 1,109
Abortion, Spontaneous 2 | 109
Alzheimer's disease 2 | 658
Becker muscular dystrophy 2 | 191
Breast Neoplasms 2 | 445
Colorectal Neoplasms 2 | 243
Coronary artery disease 2 | 268
Craniosynostosis 2 | 74
Down syndrome 2 | 499
Endometrial cancer 2 | 311
Essential Hypertension 2 | 94
Heart disease 2 | 306
Hypersensitivity reaction type II disease 2 | 253
Kidney disease 2 | 430
Liver cancer 2 | 604
Lung Neoplasms 2 | 232
Multiple Sclerosis 2 | 540
Multiple myeloma 2 | 1,332
Severe combined immunodeficiency 2 | 51
Spontaneous abortion 2 | 113
Stomach Neoplasms 2 | 300
astrocytoma 2 | 1,146
chronic rhinosinusitis 2 | 512
dermatomyositis 2 | 966
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 807
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
nasopharyngeal carcinoma 2 | 1,058
nephrosclerosis 2 | 333
pediatric high grade glioma 2 | 1,064
sonic hedgehog group medulloblastoma 2 | 467

Tissue

Blood and immune system 35 | 16,909
Cardiovascular System 35 | 15,192
Skin and soft tissues 35 | 17,230
Digestive Tract 34 | 17,369
Endocrine System 34 | 18,159
Female tissues 34 | 17,400
Liver and Pancreas 34 | 16,750
Male tissues 34 | 17,142
Nervous System 34 | 16,725
Urinary Tract 34 | 16,678
Respiratory system 33 | 16,393

Target Family

Non-IDG 23 | 12,091
Enzyme 6 | 4,145
Kinase 3 | 634
Transcription Factor 2 | 1,400
GPCR 1 | 408

GO Function

signal transducer activity, do... 35 | 35
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
BAG family molecular chaperone regulator 1 BAG1 Tbio Non-IDG -2.50252 335.1 394
Leucine-rich repeat transmembrane protein FLRT2 FLRT2 Tbio Non-IDG -1.09240 12.6 50
Interleukin-1 receptor-like 1 IL1RL1 Tbio Non-IDG -2.06895 107.0 347
Regulator of G-protein signaling 14 RGS14 Tbio Non-IDG -1.61170 43.9 233
E3 ubiquitin-protein ligase TRAIP TRAIP Tbio Enzyme -1.14146 18.0 193
Leucine-rich repeat transmembrane protein FLRT3 FLRT3 Tbio Non-IDG -1.29335 20.6 58
T-lymphoma invasion and metastasis-inducing protein 2 TIAM2 Tbio Non-IDG -1.27322 19.7 151
Serine/threonine-protein kinase DCLK1 DCLK1 Tchem Kinase -2.08177 129.5 320
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 PLCE1 Tbio Enzyme -1.96455 94.9 28
Natural cytotoxicity triggering receptor 1 NCR1 Tbio Non-IDG -2.43156 271.6 456