Development Level

Tchem 5 | 1,598
Tclin 2 | 613

Collection

Ion Channel: IDG Consortium (T... 3 | 99

IMPC Phenotype

decreased grip strength 1 | 116

Disease

Carcinoma 5 | 11,493
Chemotherapy-induced nausea and vomiting 5 | 16
Diabetic gastroparesis 5 | 7
Gastroesophageal reflux disease 5 | 110
Gastrointestinal Radiography Adjunct 5 | 11
Intubation of gastrointestinal tract 5 | 7
Prevention of Post-Operative Nausea and Vomiting 5 | 14
Schizophrenia 5 | 1,160
Irritable bowel syndrome 4 | 60
psoriasis 4 | 6,694
Alcohol dependence 3 | 107
Alcoholic Intoxication, Chronic 3 | 289
Autistic Disorder 2 | 364
Bipolar Disorder 2 | 666
Depressive disorder 2 | 409
Diarrhea 2 | 253
Dyspepsia 2 | 33
Major Depressive Disorder 2 | 301
Mental Depression 2 | 333
Nicotine dependence 2 | 54
Post-Operative Nausea and Vomiting 2 | 4
Prevention of Radiation-Induced Nausea and Vomiting 2 | 7
Primary angle-closure glaucoma 2 | 14
Unipolar Depression 2 | 250
ovarian cancer 2 | 8,520
Adenocarcinoma 1 | 122
Alcoholism 1 | 45
Amnestic disorder 1 | 35
Amphetamine-Related Disorders 1 | 74
Anxiety disorder 1 | 23
Astrocytoma, Pilocytic 1 | 3,081
Cancer 1 | 2,499
Chronic obstructive pulmonary disease 1 | 184
Cocaine Dependence 1 | 51
Constipation 1 | 181
Controlled Hypotension 1 | 6
Fibromyalgia 1 | 19
Frontal lobe epilepsy 1 | 10
Gastroparesis 1 | 22
Heroin dependence 1 | 30
Hypertensive Emergencies 1 | 10
Hypertensive disorder 1 | 56
Irritable bowel syndrome with diarrhea 1 | 3
Ischemic colitis 1 | 3
Lung Neoplasms 1 | 232
Migraine 1 | 83
Mood Disorders 1 | 184
Motion sickness 1 | 21
Muscle relaxation, function 1 | 8
Muscular Diseases 1 | 27
Myopathy 1 | 185
Pain 1 | 103
Pain agnosia 1 | 104
Pulmonary edema 1 | 17
Seizures 1 | 596
Substance abuse 1 | 59
TOBACCO ADDICTION, SUSCEPTIBILITY TO 1 | 12
TOBACCO ADDICTION, SUSCEPTIBILITY TO (finding) 1 | 12
Tobacco Use Disorder 1 | 12
alcohol use disorder 1 | 12
colon cancer 1 | 1,478
ependymoma 1 | 4,679
glioblastoma 1 | 5,792
group 3 medulloblastoma 1 | 4,104
heavy drinking 1 | 5
lung cancer 1 | 4,740
lung carcinoma 1 | 2,843
medulloblastoma, large-cell 1 | 6,241
osteosarcoma 1 | 7,950
pediatric high grade glioma 1 | 1,064
subependymal giant cell astrocytoma 1 | 2,287
substance-related disorder 1 | 162

Tissue

Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Blood and immune system 4 | 16,909
Female tissues 4 | 17,400
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678
Cardiovascular System 2 | 15,192
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142

Target Family

Ion Channel 7 | 344

GO Function

serotonin-gated cation-selecti... 7 | 7
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
5-hydroxytryptamine receptor 3B HTR3B Tchem Ion Channel -1.66753 42.0 91
5-hydroxytryptamine receptor 3C HTR3C Tchem Ion Channel -0.68931 5.03 78
5-hydroxytryptamine receptor 3A HTR3A Tclin Ion Channel -3.38661 2426.7 262
5-hydroxytryptamine receptor 3E HTR3E Tchem Ion Channel -0.83159 6.50 83
5-hydroxytryptamine receptor 3D HTR3D Tchem Ion Channel -0.55953 3.23 20
Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 Tclin Ion Channel -1.99577 92.1 193
Zinc-activated ligand-gated ion channel ZACN Tchem Ion Channel 0.27 0.96 66