Development Level

Tbio 69 | 11,445
Tdark 22 | 6,588
Tchem 4 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal epididymis morphology 2 | 42
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
enlarged heart 2 | 210
abnormal duodenum morphology 1 | 4
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal vibrissa morphology 1 | 25
absent vibrissae 1 | 12
brachydactyly 1 | 19
decreased basophil cell number 1 | 16
decreased body temperature 1 | 2
decreased circulating bilirubi... 1 | 19
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
embryonic lethality prior to t... 1 | 278
head bobbing 1 | 5
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased mean corpuscular hem... 1 | 96
increased prepulse inhibition 1 | 32
male infertility 1 | 123
premature death 1 | 5
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 57 | 11,493
psoriasis 55 | 6,694
ovarian cancer 37 | 8,520
lung cancer 30 | 4,740
medulloblastoma, large-cell 29 | 6,241
non-small cell lung cancer 27 | 2,890
lung carcinoma 26 | 2,843
osteosarcoma 26 | 7,950
Cancer 24 | 2,499
ependymoma 24 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
lung adenocarcinoma 24 | 2,716
interstitial cystitis 23 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
glioblastoma 21 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
pancreatic cancer 20 | 2,398
ulcerative colitis 20 | 1,819
Breast cancer 19 | 3,578
cystic fibrosis 19 | 1,696
malignant mesothelioma 19 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,962
adult high grade glioma 18 | 3,801
atypical teratoid / rhabdoid tumor 17 | 5,112
Autosomal recessive predisposition 15 | 1,442
Astrocytoma, Pilocytic 14 | 3,081
Atopic dermatitis 14 | 952
Kidney cancer 14 | 2,613
gastric carcinoma 14 | 807
invasive ductal carcinoma 13 | 2,951
primary pancreatic ductal adenocarcinoma 13 | 1,109
astrocytic glioma 12 | 2,597
esophageal adenocarcinoma 12 | 737
pituitary cancer 12 | 1,972
tuberculosis 12 | 2,010
Liver Cirrhosis, Experimental 11 | 769
colon cancer 11 | 1,478
group 3 medulloblastoma 11 | 4,104
nasopharyngeal carcinoma 11 | 1,058
breast carcinoma 10 | 1,638
cutaneous lupus erythematosus 10 | 1,057
primitive neuroectodermal tumor 10 | 3,035
subependymal giant cell astrocytoma 10 | 2,287
ductal carcinoma in situ 9 | 1,745
oligodendroglioma 9 | 2,850
spina bifida 9 | 1,074
Alzheimer's disease 8 | 658
Duchenne muscular dystrophy 8 | 601
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
diabetes mellitus 8 | 1,728
Cerebrovascular disease 7 | 238
Disseminated intravascular coagulation 7 | 38
Kidney disease 7 | 430
Liver Cirrhosis 7 | 181
Prostatic Neoplasms 7 | 495
fibroadenoma 7 | 559
juvenile dermatomyositis 7 | 1,187
Bipolar Disorder 6 | 666
Breast Neoplasms 6 | 445
Chronic obstructive pulmonary disease 6 | 184
Liver disease 6 | 237
Mammary Neoplasms 6 | 425
Melanoma 6 | 711
Multiple Sclerosis 6 | 540
acute quadriplegic myopathy 6 | 1,158
adrenocortical carcinoma 6 | 1,428
Atherosclerosis 5 | 291
Carcinoma, Hepatocellular 5 | 228
Chemical and Drug Induced Liver Injury 5 | 195
Colorectal Neoplasms 5 | 243
Coronary artery disease 5 | 268
Depressive disorder 5 | 409
Diarrhea 5 | 253
Hypertension 5 | 396
Liver carcinoma 5 | 240
Lung disease 5 | 142
Pick disease 5 | 1,894
Schizophrenia 5 | 1,160
Thrombophilia 5 | 38
Vascular disease 5 | 319
active ulcerative colitis 5 | 764
astrocytoma 5 | 1,146
primary Sjogren syndrome 5 | 735
sonic hedgehog group medulloblastoma 5 | 467
Asthma 4 | 385
Cholestasis 4 | 155
Colonic Neoplasms 4 | 142
Contact Dermatitis 4 | 81
Dementia 4 | 175
Heart disease 4 | 306
Mental Depression 4 | 333
Polycystic ovary syndrome 4 | 360
Rheumatoid arthritis 4 | 1,191
Seizures 4 | 596
Skin cancer 4 | 469
dermatomyositis 4 | 966
head and neck cancer 4 | 271
nephrosclerosis 4 | 333
pterygium 4 | 76
urothelial carcinoma 4 | 318

Tissue

Male tissues 87 | 17,142
Digestive Tract 86 | 17,369
Endocrine System 86 | 18,159
Female tissues 86 | 17,400
Skin and soft tissues 84 | 17,230
Blood and immune system 78 | 16,909
Liver and Pancreas 78 | 16,750
Urinary Tract 77 | 16,678
Respiratory system 75 | 16,393
Nervous System 67 | 16,725
Cardiovascular System 63 | 15,192

Target Family

Non-IDG 76 | 12,091
Enzyme 20 | 4,145

GO Function

serine-type endopeptidase inhi... 96 | 96
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-1-antichymotrypsin SERPINA3 Tbio Non-IDG -2.94780 812.7 276
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.74914 5601.8 1083
Collagen alpha-1(XXVIII) chain COL28A1 Tdark Non-IDG 0.78 0.10 6
Serpin A9 SERPINA9 Tbio Non-IDG -1.94929 88.4 132
Serpin B12 SERPINB12 Tbio Non-IDG -0.56624 4.27 155
Leukocyte elastase inhibitor SERPINB1 Tbio Enzyme -2.55345 336.3 370
ProSAAS PCSK1N Tbio Non-IDG -2.28833 188.0 73
WAP four-disulfide core domain protein 6 WFDC6 Tdark Non-IDG -0.03476 0.74 2
CD109 antigen CD109 Tbio Non-IDG -1.85817 77.8 239
WAP four-disulfide core domain protein 12 WFDC12 Tbio Non-IDG -0.92987 8.23 54