Development Level

Tbio 5 | 11,445
Tchem 4 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

decreased grip strength 2 | 116
abnormal heart morphology 1 | 162
abnormal locomotor behavior 1 | 24
aorta stenosis 1 | 2
decreased food intake 1 | 13
enlarged heart 1 | 210
enlarged liver 1 | 2
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased fasted circulating g... 1 | 76
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 8 | 11,493
ovarian cancer 8 | 8,520
glioblastoma 7 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
Breast cancer 5 | 3,578
diabetes mellitus 5 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
lung cancer 5 | 4,740
astrocytoma 4 | 1,146
cystic fibrosis 4 | 1,696
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
medulloblastoma, large-cell 4 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Kidney cancer 3 | 2,613
adult high grade glioma 3 | 3,801
ependymoma 3 | 4,679
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
juvenile dermatomyositis 3 | 1,187
lung adenocarcinoma 3 | 2,716
pancreatic cancer 3 | 2,398
primary pancreatic ductal adenocarcinoma 3 | 1,109
psoriasis 3 | 6,694
subependymal giant cell astrocytoma 3 | 2,287
Angioedema 2 | 38
Astrocytoma, Pilocytic 2 | 3,081
Atopic dermatitis 2 | 952
Autosomal recessive predisposition 2 | 1,442
Duchenne muscular dystrophy 2 | 601
active Crohn's disease 2 | 922
acute myeloid leukemia 2 | 783
adrenocortical carcinoma 2 | 1,428
atypical teratoid / rhabdoid tumor 2 | 5,112
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
gastric carcinoma 2 | 807
group 3 medulloblastoma 2 | 4,104
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
osteosarcoma 2 | 7,950
pituitary cancer 2 | 1,972
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Abnormal skeletal development 1 | 60
Abnormality of metabolism/homeostasis 1 | 134
Allergic rhinitis 1 | 94
Angiokeratoma 1 | 9
Atherosclerosis 1 | 291
Cataract 8 multiple types 1 | 33
Cerebral palsy 1 | 40
Clouding of corneal stroma 1 | 50
Coarse facial features 1 | 108
Common cold 1 | 67
Congenital deafness 1 | 185
Conjunctival telangiectasis 1 | 14
Corneal Opacity 1 | 53
Corneal dystrophy 1 | 24
Cough 1 | 23
Deafness 1 | 198
Dermatologic disorders 1 | 93
Diarrhea 1 | 253
Dwarfism 1 | 37
Epilepsy 1 | 792
Gastroschisis 1 | 11
Gaucher disease type 1 1 | 180
Hearing Loss, Partial 1 | 185
Hemangioma 1 | 69
Hepatitis B 1 | 108
Holoprosencephaly 1 | 56
Insulin Resistance 1 | 72
Isolated cleft palate 1 | 4
Leber congenital amaurosis 1 | 69
Liver Cirrhosis 1 | 181
Lung Neoplasms 1 | 232
Macular degeneration 1 | 65
Osteochondrodysplasias 1 | 72
Osteoporosis 1 | 363
Pearson syndrome 1 | 19
Pfaundler-Hurler Syndrome 1 | 12
Retinitis pigmentosa 3 1 | 16
Rhinitis 1 | 54
Seizures 1 | 596
Thickened facial skin with coarse facial features 1 | 108
Type 2 diabetes mellitus 1 | 272
Yaws 1 | 7
active ulcerative colitis 1 | 764
facioscapulohumeral dystrophy 1 | 288
fascioscapulohumeral muscular dystrophy 1 | 100
glioblastoma multiforme 1 | 142
head and neck cancer 1 | 271
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
hearing impairment 1 | 199
interstitial lung disease 1 | 298
pediatric high grade glioma 1 | 1,064
posterior fossa group A ependymoma 1 | 468
progressive supranuclear palsy 1 | 676
type II diabetes mellitus and post-ischemic heart failure 1 | 88

Tissue

Endocrine System 10 | 18,159
Liver and Pancreas 10 | 16,750
Urinary Tract 10 | 16,678
Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Female tissues 9 | 17,400
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230

Target Family

Enzyme 9 | 4,145
Non-IDG 1 | 12,091

GO Function

serine-type carboxypeptidase a... 10 | 10
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lysosomal Pro-X carboxypeptidase PRCP Tchem Enzyme -1.87633 85.9 165
Carboxypeptidase E CPE Tbio Enzyme -3.01460 1019.8 229
Adipocyte enhancer-binding protein 1 AEBP1 Tbio Non-IDG -1.54371 39.5 142
Lysosomal protective protein CTSA Tchem Enzyme -3.07101 1162.7 300
Carboxypeptidase M CPM Tchem Enzyme -2.14474 133.2 196
Carboxypeptidase N catalytic chain CPN1 Tchem Enzyme -2.71738 529.1 145
Carboxypeptidase Z CPZ Tdark Enzyme -1.86592 72.7 37
Probable serine carboxypeptidase CPVL CPVL Tbio Enzyme -1.89400 74.4 135
Retinoid-inducible serine carboxypeptidase SCPEP1 Tbio Enzyme -0.79414 6.75 61
Carboxypeptidase D CPD Tbio Enzyme -1.58162 36.7 63