Development Level

Tbio 8 | 11,445
Tclin 2 | 613

IMPC Phenotype

abnormal coat-hair pigmentatio... 1 | 64
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating creatini... 1 | 38
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

ovarian cancer 7 | 8,520
psoriasis 7 | 6,694
medulloblastoma, large-cell 6 | 6,241
Carcinoma 5 | 11,493
atypical teratoid / rhabdoid tumor 5 | 5,112
group 3 medulloblastoma 5 | 4,104
lung cancer 5 | 4,740
osteosarcoma 5 | 7,950
primitive neuroectodermal tumor 5 | 3,035
acute quadriplegic myopathy 4 | 1,158
adult high grade glioma 4 | 3,801
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
non-small cell lung cancer 4 | 2,890
Breast cancer 3 | 3,578
Cancer 3 | 2,499
Multiple myeloma 3 | 1,332
breast carcinoma 3 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
juvenile dermatomyositis 3 | 1,187
lung adenocarcinoma 3 | 2,716
malignant mesothelioma 3 | 3,232
progressive supranuclear palsy 3 | 676
subependymal giant cell astrocytoma 3 | 2,287
Adverse reaction to drug 2 | 61
Astrocytoma, Pilocytic 2 | 3,081
Autistic Disorder 2 | 364
Bipolar Disorder 2 | 666
Breast Neoplasms 2 | 445
Cerebral atrophy 2 | 178
Cognitive delay 2 | 608
Colorectal Neoplasms 2 | 243
Down syndrome 2 | 499
Drug-Related Side Effects and Adverse Reactions 2 | 62
Endometriosis 2 | 540
Global developmental delay 2 | 608
Lupus erythematosus 2 | 57
Malignant mesothelioma of pleura 2 | 7
Mammary Neoplasms 2 | 425
Mental and motor retardation 2 | 608
Muscle hypotonia 2 | 571
Nervous System Diseases 2 | 53
Pick disease 2 | 1,894
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
fibroadenoma 2 | 559
nervous system disorder 2 | 53
oligodendroglioma 2 | 2,850
pituitary cancer 2 | 1,972
tuberculosis 2 | 2,010
Acquired flat foot 1 | 72
Actinic keratosis 1 | 21
Action Tremor 1 | 22
Atrioventricular block 1 | 35
Cell Transformation, Neoplastic 1 | 97
Cerebellar Dysmetria 1 | 56
Congenital Abnormalities 1 | 11
Congenital Abnormality 1 | 11
Corneal edema 1 | 14
Cryptosporidiosis 1 | 13
Dysdiadochokinesis 1 | 25
Ehrlichiosis 1 | 9
Elevated gonadotropins 1 | 15
Erectile dysfunction 1 | 32
Exanthem 1 | 37
Flatfoot 1 | 73
Fragile 10 Mental Retardation Syndrome 1 | 2
Gynecomastia 1 | 64
Head and Neck Neoplasms 1 | 26
Joint laxity 1 | 54
Juvenile rheumatoid arthritis 1 | 111
Malignant tumor of colon 1 | 19
Malignant tumor of lung 1 | 5
Meningeal Leukemia 1 | 7
Metastasis from malignant tumor of colon 1 | 8
Mild Mental Retardation 1 | 70
Mitral Valve Prolapse Syndrome 1 | 39
Mood instability 1 | 2
Narrow face 1 | 54
Neoplasms 1 | 63
Neoplastic Cell Transformation 1 | 89
Obesity, Abdominal 1 | 24
Obsessive compulsive behavior 1 | 25
Osteosarcoma of bone 1 | 6
Paranasal Sinus Diseases 1 | 34
Periventricular neuronal heterotopia 1 | 6
Pneumocystosis 1 | 17
Poor eye contact 1 | 12
Poor head control 1 | 14
Postnatal microcephaly 1 | 24
Sinusitis 1 | 65
Small hand 1 | 36
Static Tremor 1 | 21
Terminal tremor 1 | 20
Thin face 1 | 54
Von Willebrand's disease 1 | 19

Tissue

Blood and immune system 10 | 16,909
Cardiovascular System 10 | 15,192
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678

Target Family

Enzyme 4 | 4,145
Non-IDG 4 | 12,091
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

GO Function

sequence-specific mRNA binding 10 | 10
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
La-related protein 6 LARP6 Tbio Non-IDG -1.42450 28.5 86
Eukaryotic peptide chain release factor subunit 1 ETF1 Tbio Enzyme -1.75590 53.5 113
Thymidylate synthase TYMS Tclin Enzyme -2.93426 732.0 733
ATP-dependent RNA helicase A DHX9 Tbio Enzyme -2.85807 734.3 204
Serine/arginine-rich splicing factor 3 SRSF3 Tbio Non-IDG -1.86517 74.7 216
Dihydrofolate reductase DHFR Tclin Enzyme -2.99192 972.8 202
Serine/arginine-rich splicing factor 4 SRSF4 Tbio Non-IDG -1.15894 11.6 103
Lupus La protein SSB Tbio Non-IDG -2.51632 289.3 331
Protein lin-28 homolog A LIN28A Tbio Transcription Factor -2.44709 277.0 494
Synaptic functional regulator FMR1 FMR1 Tbio Epigenetic -3.38241 2443.7 484