Development Level

Tbio 284 | 10,625
Tdark 73 | 7,003
Tchem 33 | 1,890
Tclin 8 | 602

IMPC Term

preweaning lethality, complete... 11 | 633
preweaning lethality, incomple... 8 | 260
embryonic lethality prior to t... 6 | 187
abnormal embryo size 4 | 112
decreased circulating triglyce... 4 | 83
decreased hemoglobin content 4 | 53
increased circulating alkaline... 4 | 119
abnormal forebrain development 3 | 18
abnormal hindbrain development 3 | 24
abnormal neural tube closure 3 | 37
abnormal retina morphology 3 | 100
decreased circulating insulin ... 3 | 75
decreased grip strength 3 | 123
decreased total body fat amoun... 3 | 186
hypoactivity 3 | 89
increased circulating HDL chol... 3 | 63
increased exploration in new e... 3 | 56
increased or absent threshold ... 3 | 128
abnormal behavior 2 | 226
abnormal bone structure 2 | 131
abnormal embryo turning 2 | 15
abnormal eye morphology 2 | 38
abnormal midbrain development 2 | 22
abnormal pharyngeal arch morph... 2 | 2
corneal opacity 2 | 25
decreased CD4-positive, alpha ... 2 | 19
decreased T cell number 2 | 31
decreased body length 2 | 108
decreased body weight 2 | 174
decreased bone mineral density 2 | 126
decreased circulating alanine ... 2 | 53
decreased circulating alkaline... 2 | 41
decreased circulating choleste... 2 | 85
decreased circulating fructosa... 2 | 31
decreased circulating glucose ... 2 | 121
decreased circulating glycerol... 2 | 19
decreased circulating serum al... 2 | 79
decreased erythrocyte cell num... 2 | 43
decreased lean body mass 2 | 195
decreased mature B cell number 2 | 25
decreased prepulse inhibition 2 | 52
embryonic growth retardation 2 | 28
embryonic lethality prior to o... 2 | 148
enlarged heart 2 | 111
female infertility 2 | 34
increased B cell number 2 | 23
increased bone mineral content 2 | 92
increased circulating glucose ... 2 | 16
increased lactate dehydrogenas... 2 | 3
increased mean corpuscular hem... 2 | 93
increased mean corpuscular vol... 2 | 91
persistence of hyaloid vascula... 2 | 22
syndactyly 2 | 4
thick ventricular wall 2 | 7
thrombocytopenia 2 | 46
trunk curl 2 | 15
abnormal allantois morphology 1 | 3
abnormal behavioral response t... 1 | 52
abnormal coat/ hair morphology 1 | 18
abnormal cornea morphology 1 | 24
abnormal gait 1 | 51
abnormal heart looping 1 | 2
abnormal heart morphology 1 | 51
abnormal locomotor activation 1 | 26
abnormal neural tube morpholog... 1 | 8
abnormal optic disc morphology 1 | 10
abnormal retinal pigmentation 1 | 61
abnormal spleen morphology 1 | 36
abnormal tail bud morphology 1 | 6
cataract 1 | 26
decreased CD8-positive, alpha-... 1 | 26
decreased IgE level 1 | 3
decreased blood urea nitrogen ... 1 | 31
decreased circulating chloride... 1 | 32
decreased circulating sodium l... 1 | 18
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased rib number 1 | 59
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating triglyce... 1 | 24
increased fasted circulating g... 1 | 68
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 25
increased respiratory quotient 1 | 12
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
limb grasping 1 | 35
polycystic kidney 1 | 9
prenatal lethality prior to he... 1 | 64
short tail 1 | 4
short tibia 1 | 82
small superior vagus ganglion 1 | 20
thin ventricular wall 1 | 5
tremors 1 | 34
vertebral fusion 1 | 23

Disease

osteosarcoma 169 | 7,933
ovarian cancer 161 | 8,484
psoriasis 149 | 6,685
medulloblastoma, large-cell 133 | 6,234
glioblastoma 108 | 5,572
lung cancer 100 | 4,466
atypical teratoid / rhabdoid tumor 95 | 4,369
malignant mesothelioma 87 | 3,162
Cancer 83 | 2,346
invasive ductal carcinoma 70 | 2,950
Breast cancer 69 | 3,094
primitive neuroectodermal tumor 61 | 3,031
interstitial cystitis 59 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 58 | 3,289
non-small cell lung cancer 57 | 2,798
group 4 medulloblastoma 51 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 51 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 49 | 2,956
adult high grade glioma 48 | 2,148
cystic fibrosis 47 | 1,665
lung adenocarcinoma 47 | 2,713
pediatric high grade glioma 47 | 2,712
pilocytic astrocytoma 47 | 3,086
oligodendroglioma 46 | 2,849
breast carcinoma 45 | 1,614
ulcerative colitis 44 | 2,087
ductal carcinoma in situ 42 | 1,745
pancreatic cancer 42 | 2,300
group 3 medulloblastoma 39 | 2,254
pituitary cancer 39 | 1,972
ependymoma 38 | 2,514
Carcinoma 37 | 2,147
Rheumatoid Arthritis 36 | 1,160
lung carcinoma 35 | 2,844
astrocytic glioma 33 | 2,241
sonic hedgehog group medulloblastoma 32 | 1,482
subependymal giant cell astrocytoma 32 | 2,287
Pick disease 31 | 1,893
astrocytoma 30 | 1,493
colon cancer 30 | 1,475
medulloblastoma 29 | 1,524
primary pancreatic ductal adenocarcinoma 28 | 1,271
Craniofacial Abnormalities 26 | 147
posterior fossa group B ependymoma 26 | 1,530
spina bifida 26 | 1,064
tuberculosis 26 | 1,557
posterior fossa group A ependymoma 25 | 1,511
Mammary Neoplasms 24 | 410
adrenocortical carcinoma 24 | 1,427
cutaneous lupus erythematosus 24 | 1,056
diabetes mellitus 24 | 1,663
juvenile dermatomyositis 24 | 1,189
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,795
gastric carcinoma 22 | 832
dermatomyositis 21 | 933
Multiple myeloma 19 | 1,327
Obesity 19 | 616
acute quadriplegic myopathy 19 | 1,157
primary Sjogren syndrome 19 | 789
Cleft palate 18 | 125
acute myeloid leukemia 17 | 780
Intellectual disability 16 | 573
Prostatic Neoplasms 16 | 471
Endometriosis 15 | 535
inflammatory breast cancer 15 | 404
Atopic dermatitis 14 | 944
atypical teratoid/rhabdoid tumor 14 | 1,095
non primary Sjogren syndrome sicca 14 | 840
aldosterone-producing adenoma 13 | 664
fibroadenoma 13 | 557
hepatocellular carcinoma 13 | 532
tuberculosis and treatment for 6 months 13 | 686
urothelial carcinoma 13 | 318
Crohn's disease 12 | 304
autosomal dominant Emery-Dreifuss muscular dystrophy 12 | 499
progressive supranuclear palsy 12 | 674
Bipolar Disorder 11 | 266
Cleft Lip 11 | 91
Holoprosencephaly 11 | 52
Kidney disease 11 | 396
Metabolic syndrome X 11 | 155
Prostate cancer 11 | 172
nasopharyngeal carcinoma 11 | 1,056
Amyotrophic Lateral Sclerosis 10 | 431
Congenital heart disease 10 | 63
Multiple Sclerosis 10 | 498
Schizophrenia 10 | 501
Alzheimer's disease 9 | 644
Cardiovascular system disease 9 | 194
Down syndrome 9 | 548
Duchenne muscular dystrophy 9 | 602
Melanoma 9 | 261
Polydactyly 9 | 93
Syndactyly 9 | 56
Waldenstrons macroglobulinemia 9 | 765
active ulcerative colitis 9 | 477
esophageal adenocarcinoma 9 | 737
facioscapulohumeral dystrophy 9 | 286
nephrosclerosis 9 | 329
pancreatic carcinoma 9 | 567

Tissue

Female tissues 387 | 18,647
Endocrine System 386 | 18,512
Nervous System 384 | 18,561
Digestive Tract 383 | 18,473
Skin and soft tissues 380 | 18,115
Urinary Tract 376 | 18,444
Male tissues 374 | 17,969
Blood and immune system 368 | 17,995
Cardiovascular System 366 | 17,958
Liver and Pancreas 366 | 18,136
Respiratory system 344 | 17,484

Target Family

Transcription Factor 315 | 1,400
Non-IDG 46 | 11,971
Nuclear Receptor 24 | 48
Epigenetic 7 | 242
TF/Epigenetic 4 | 38
Enzyme 1 | 4,146
Kinase 1 | 634

GO Function

sequence-specific DNA binding 398 | 398
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Forkhead box protein M1 FOXM1 Tbio Transcription Factor -3.09305 1275.4 345
Basic helix-loop-helix transcription factor scleraxis SCX Tbio Transcription Factor -2.80657 344.1 42
Zinc finger protein 148 ZNF148 Tbio Transcription Factor -1.71996 60.7 178
V(D)J recombination-activating protein 1 RAG1 Tbio Non-IDG -3.00063 1061.1 65
Erythroid transcription factor GATA1 Tbio Transcription Factor -2.97791 941.1 675
Zinc finger and BTB domain-containing protein 14 ZBTB14 Tbio Transcription Factor -1.28934 22.1 38
Double homeobox protein 1 DUX1 Tdark Non-IDG 0.00000 0
LIM/homeobox protein Lhx2 LHX2 Tbio Transcription Factor -1.89097 87.7 161
Transcriptional repressor p66-alpha GATAD2A Tbio Non-IDG -0.79314 7.11 142
Transcription factor SOX-30 SOX30 Tbio Transcription Factor -0.69660 5.92 144