Development Level

Tbio 38 | 11,651
Tchem 7 | 1,388
Tdark 5 | 6,593

IMPC Phenotype

decreased total body fat amoun... 3 | 207
cardiovascular system phenotyp... 2 | 36
decreased vertical activity 2 | 208
enlarged spleen 2 | 41
preweaning lethality, complete... 2 | 979
prolonged QT interval 2 | 38
abnormal QT variability 1 | 10
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal limb bud morphology 1 | 17
abnormal nail morphology 1 | 8
abnormal pericardium morpholog... 1 | 26
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
anophthalmia 1 | 33
decreased body length 1 | 101
decreased body weight 1 | 161
decreased cardiac muscle contr... 1 | 11
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased exploration in new e... 1 | 11
decreased heart rate 1 | 18
decreased heart rate variabili... 1 | 13
decreased total retina thickne... 1 | 17
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
pallor 1 | 34
prolonged PQ interval 1 | 5
prolonged QRS complex duration 1 | 8
small kidney 1 | 16
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56

Disease

Carcinoma 43 | 11,493
ovarian cancer 28 | 8,520
osteosarcoma 23 | 7,950
psoriasis 21 | 6,694
Breast cancer 19 | 3,578
lung carcinoma 19 | 2,843
lung adenocarcinoma 18 | 2,716
Kidney cancer 16 | 2,613
lung cancer 16 | 4,740
glioblastoma 15 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
ependymoma 14 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
non-small cell lung cancer 14 | 2,890
Cancer 12 | 2,499
group 3 medulloblastoma 12 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
medulloblastoma, large-cell 12 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Astrocytoma, Pilocytic 11 | 3,081
invasive ductal carcinoma 11 | 2,951
pancreatic cancer 11 | 2,398
cystic fibrosis 10 | 1,696
ductal carcinoma in situ 10 | 1,745
adrenocortical carcinoma 9 | 1,428
adult high grade glioma 9 | 3,801
interstitial cystitis 9 | 2,312
malignant mesothelioma 9 | 3,232
subependymal giant cell astrocytoma 9 | 2,287
tuberculosis 9 | 2,010
Liver Cirrhosis, Experimental 8 | 769
Melanoma 8 | 711
Syndromic X-linked intellectual disability Snyder type 8 | 21
juvenile dermatomyositis 8 | 1,187
pituitary cancer 8 | 1,972
Atherosclerosis 7 | 291
Skin cancer 7 | 469
colon cancer 7 | 1,478
diabetes mellitus 7 | 1,728
fibroadenoma 7 | 559
oligodendroglioma 7 | 2,850
ulcerative colitis 7 | 1,819
Atopic dermatitis 6 | 952
Autosomal recessive predisposition 6 | 1,442
Duchenne muscular dystrophy 6 | 601
Rheumatoid arthritis 6 | 1,191
Schizophrenia 6 | 1,160
atypical teratoid / rhabdoid tumor 6 | 5,112
breast carcinoma 6 | 1,638
cutaneous lupus erythematosus 6 | 1,057
active ulcerative colitis 5 | 764
astrocytic glioma 5 | 2,597
esophageal adenocarcinoma 5 | 737
mucosa-associated lymphoid tissue lymphoma 5 | 484
Chronic obstructive pulmonary disease 4 | 184
Endometrial cancer 4 | 311
Endometriosis 4 | 540
aldosterone-producing adenoma 4 | 665
astrocytoma 4 | 1,146
dermatomyositis 4 | 966
gastric carcinoma 4 | 807
nasopharyngeal carcinoma 4 | 1,058
spina bifida 4 | 1,074
urothelial carcinoma 4 | 318
Arthritis 3 | 290
Arthritis, Rheumatoid 3 | 174
Barrett's esophagus 3 | 182
Becker muscular dystrophy 3 | 191
Coronary artery disease 3 | 268
Crohn's disease 3 | 321
Hepatitis C 3 | 94
Liver cancer 3 | 604
Liver disease 3 | 237
Nonsyndromic deafness 3 | 142
Obesity 3 | 678
Osteoarthritis 3 | 184
Thrombocytopenia 3 | 197
active Crohn's disease 3 | 922
chronic rhinosinusitis 3 | 512
group 4 medulloblastoma 3 | 1,855
head and neck cancer and chronic obstructive pulmonary disease 3 | 239
posterior fossa group A ependymoma 3 | 468
primitive neuroectodermal tumor 3 | 3,035
Abortion, Spontaneous 2 | 109
Alzheimer's disease 2 | 658
Craniosynostosis 2 | 74
Kidney disease 2 | 430
Multiple Sclerosis 2 | 540
Prostate cancer 2 | 175
Prostatic Neoplasms 2 | 495
Spontaneous abortion 2 | 113
acute quadriplegic myopathy 2 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
chronic lymphosyte leukemia 2 | 204
head and neck cancer 2 | 271
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
periodontitis 2 | 293
primary pancreatic ductal adenocarcinoma 2 | 1,109
progressive supranuclear palsy 2 | 676

Tissue

Digestive Tract 49 | 17,369
Endocrine System 49 | 18,159
Liver and Pancreas 49 | 16,750
Skin and soft tissues 49 | 17,230
Female tissues 48 | 17,400
Blood and immune system 47 | 16,909
Nervous System 47 | 16,725
Urinary Tract 46 | 16,678
Male tissues 45 | 17,142
Respiratory system 45 | 16,393
Cardiovascular System 40 | 15,192

Target Family

Non-IDG 33 | 12,091
Enzyme 13 | 4,145
GPCR 3 | 408
Transcription Factor 1 | 1,400

GO Function

scavenger receptor activity 50 | 50
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Macrophage receptor MARCO MARCO Tbio Non-IDG -2.37206 210.3 189
Neurotrypsin PRSS12 Tbio Non-IDG -1.46986 30.6 77
Platelet glycoprotein 4 CD36 Tbio Non-IDG -2.63884 376.0 1155
Stabilin-2 STAB2 Tbio Non-IDG -2.81864 640.7 72
Tubulointerstitial nephritis antigen TINAG Tbio Non-IDG -1.39157 27.8 58
Lysyl oxidase homolog 2 LOXL2 Tbio Enzyme -2.24186 173.0 274
Atypical chemokine receptor 3 ACKR3 Tchem GPCR -1.91187 99.0 476
Scavenger receptor class A member 5 SCARA5 Tbio Non-IDG -1.39965 26.2 118
Galectin-3-binding protein LGALS3BP Tbio Non-IDG -2.87615 736.2 222
Somatomedin-B and thrombospondin type-1 domain-containing protein SBSPON Tdark Non-IDG -0.45864 2.91 57