Development Level

Tbio 14 | 11,445
Tchem 3 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal skin morphology 1 | 50

Disease

psoriasis 12 | 6,694
osteosarcoma 10 | 7,950
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
Carcinoma 8 | 11,493
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
lung cancer 8 | 4,740
ovarian cancer 8 | 8,520
glioblastoma 7 | 5,792
Astrocytoma, Pilocytic 6 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
medulloblastoma, large-cell 6 | 6,241
ependymoma 5 | 4,679
interstitial cystitis 5 | 2,312
lung adenocarcinoma 5 | 2,716
Atopic dermatitis 4 | 952
adrenocortical carcinoma 4 | 1,428
colon cancer 4 | 1,478
invasive ductal carcinoma 4 | 2,951
lung carcinoma 4 | 2,843
non-small cell lung cancer 4 | 2,890
tuberculosis 4 | 2,010
Aicardi-Goutieres syndrome 3 | 19
Asthma 3 | 385
Autosomal recessive predisposition 3 | 1,442
Breast cancer 3 | 3,578
Cancer 3 | 2,499
Kidney cancer 3 | 2,613
Muscle Spasticity 3 | 195
adult high grade glioma 3 | 3,801
astrocytoma 3 | 1,146
atypical teratoid / rhabdoid tumor 3 | 5,112
cutaneous lupus erythematosus 3 | 1,057
fibroadenoma 3 | 559
group 3 medulloblastoma 3 | 4,104
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Allergic hypersensitivity disease 2 | 126
Allergic rhinitis 2 | 94
Arhinencephaly 2 | 5
Churg-Strauss syndrome 2 | 5
Coloboma of eyelid 2 | 15
Duchenne muscular dystrophy 2 | 601
Eosinophilic esophagitis 2 | 16
Hemiplegia and hemiparesis 2 | 38
Hypereosinophilic syndrome 2 | 71
Hypertension 2 | 396
Leukodystrophy 2 | 55
Lung Neoplasms 2 | 232
Lung disease 2 | 142
Obesity 2 | 678
Pick disease 2 | 1,894
Porencephaly 2 | 20
Profound Mental Retardation 2 | 31
Profound intellectual disabilities 2 | 31
Prostatic Neoplasms 2 | 495
Sinusitis 2 | 65
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
acute myeloid leukemia 2 | 783
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
group 4 medulloblastoma 2 | 1,855
inflammatory breast cancer 2 | 286
limb girdle muscular dystrophy 2A 2 | 213
malignant mesothelioma 2 | 3,232
oligodendroglioma 2 | 2,850
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 735
primary pancreatic ductal adenocarcinoma 2 | 1,109
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
AMYOTROPHIC LATERAL SCLEROSIS 1 1 | 49
Acquired metabolic disease 1 | 336
Anxiety 1 | 136
Anxiety disease 1 | 113
Brain disease 1 | 96
Bronchitis 1 | 43
Decreased platelet count 1 | 111
Degenerative brain disorder 1 | 100
Distal amyotrophy 1 | 51
Fatigue 1 | 182
Global developmental delay, severe 1 | 47
Liver diseases 1 | 87
Mood swings 1 | 77
Nerve Degeneration 1 | 121
Neuro-degenerative disease 1 | 43
Neurodegenerative Disorders 1 | 79
Pain agnosia 1 | 104
Respiratory Failure 1 | 104
Severe psychomotor retardation 1 | 47
Supratentorial atrophy 1 | 94
Thrombocytopenia 1 | 197
Thyrotoxicosis 1 | 38
fascioscapulohumeral muscular dystrophy 1 | 100
head and neck cancer and chronic obstructive pulmonary disease 1 | 239

Tissue

Blood and immune system 17 | 16,909
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Cardiovascular System 15 | 15,192

Target Family

Enzyme 13 | 4,145
Non-IDG 3 | 12,091
Kinase 1 | 634

GO Function

ribonuclease activity 17 | 17
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endoribonuclease ZC3H12A ZC3H12A Tbio Enzyme -1.81028 77.8 134
Protein SMG5 SMG5 Tbio Non-IDG -1.02024 9.67 88
Ribonuclease 4 RNASE4 Tbio Enzyme -0.99207 6.71 56
Ribonuclease H2 subunit A RNASEH2A Tbio Enzyme -2.17825 146.7 124
Ribonuclease K6 RNASE6 Tbio Enzyme -0.97895 10.0 59
Protein SMG7 SMG7 Tbio Non-IDG -1.17329 16.2 66
DIS3-like exonuclease 2 DIS3L2 Tbio Enzyme -1.32394 21.5 118
Serine/threonine-protein kinase/endoribonuclease IRE2 ERN2 Tbio Kinase -1.29793 19.9 175
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 SAMHD1 Tbio Enzyme -3.96722 8709.0 274
Zinc-alpha-2-glycoprotein AZGP1 Tbio Non-IDG -2.20244 178.8 228