Development Level

Tbio 24 | 11,445
Tchem 5 | 1,598
Tclin 5 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal lens morphology 2 | 81
cataract 2 | 92
increased circulating HDL chol... 2 | 80
abnormal bone mineralization 1 | 38
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal startle reflex 1 | 15
cardiovascular system phenotyp... 1 | 36
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating magnesiu... 1 | 13
decreased circulating serum al... 1 | 82
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
fusion of vertebral arches 1 | 7
hypoactivity 1 | 132
impaired righting response 1 | 26
increased bone mineral density 1 | 72
increased circulating choleste... 1 | 66
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 32
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
preweaning lethality, incomple... 1 | 499
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

Cancer 25 | 2,499
ovarian cancer 24 | 8,520
Carcinoma 21 | 11,493
osteosarcoma 21 | 7,950
glioblastoma 16 | 5,792
atypical teratoid / rhabdoid tumor 15 | 5,112
ependymoma 14 | 4,679
medulloblastoma, large-cell 14 | 6,241
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
primitive neuroectodermal tumor 13 | 3,035
lung cancer 12 | 4,740
psoriasis 12 | 6,694
tuberculosis 12 | 2,010
Multiple myeloma 11 | 1,332
group 3 medulloblastoma 11 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
malignant mesothelioma 10 | 3,232
Breast cancer 9 | 3,578
adult high grade glioma 9 | 3,801
invasive ductal carcinoma 9 | 2,951
oligodendroglioma 9 | 2,850
Schizophrenia 8 | 1,160
lung adenocarcinoma 8 | 2,716
subependymal giant cell astrocytoma 8 | 2,287
Astrocytoma, Pilocytic 7 | 3,081
astrocytic glioma 7 | 2,597
diabetes mellitus 7 | 1,728
group 4 medulloblastoma 7 | 1,855
lung carcinoma 7 | 2,843
non-small cell lung cancer 7 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Alzheimer's disease 6 | 658
Osteoporosis 6 | 363
Waldenstrons macroglobulinemia 6 | 765
astrocytoma 6 | 1,146
interstitial cystitis 6 | 2,312
pancreatic cancer 6 | 2,398
primary pancreatic ductal adenocarcinoma 6 | 1,109
Kidney cancer 5 | 2,613
Peripheral T-cell lymphoma 5 | 25
Primary cutaneous T-cell lymphoma 5 | 29
Rheumatoid arthritis 5 | 1,191
Small head 5 | 374
acute myeloid leukemia 5 | 783
adrenocortical carcinoma 5 | 1,428
cystic fibrosis 5 | 1,696
pediatric high grade glioma 5 | 1,064
ulcerative colitis 5 | 1,819
Brachydactyly 4 | 156
Carcinoma, Hepatocellular 4 | 228
Cognitive delay 4 | 608
Depressive disorder 4 | 409
Epilepsy 4 | 792
Failure to gain weight 4 | 365
Global developmental delay 4 | 608
Liver carcinoma 4 | 240
Mental Depression 4 | 333
Mental and motor retardation 4 | 608
Neoplasm Invasiveness 4 | 161
Neoplasm Metastasis 4 | 168
Pediatric failure to thrive 4 | 365
Seizures 4 | 596
Short stature 4 | 531
Strabismus 4 | 270
Vascular disease 4 | 319
colon cancer 4 | 1,478
gastric carcinoma 4 | 807
Acquired scoliosis 3 | 281
Arthritis 3 | 290
Arthritis, Rheumatoid 3 | 174
Breast Neoplasms 3 | 445
Colonic Neoplasms 3 | 142
Colorectal Neoplasms 3 | 243
Concave bridge of nose 3 | 195
Crohn's disease 3 | 321
Curvature of spine 3 | 282
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Disease Progression 3 | 136
Frontal bossing 3 | 157
Isolated cases 3 | 72
Liver Cirrhosis, Experimental 3 | 769
Lung disease 3 | 142
Mammary Neoplasms 3 | 425
Mood Disorders 3 | 184
Multiple Sclerosis 3 | 540
Myocardial Ischemia 3 | 169
Pick disease 3 | 1,894
Polycystic ovary syndrome 3 | 360
Recurrent respiratory infections 3 | 141
Type 2 diabetes mellitus 3 | 272
acute quadriplegic myopathy 3 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
ductal carcinoma in situ 3 | 1,745
hearing impairment 3 | 199
juvenile dermatomyositis 3 | 1,187
medulloblastoma 3 | 720
nasopharyngeal carcinoma 3 | 1,058
primary Sjogren syndrome 3 | 735

Tissue

Endocrine System 33 | 18,159
Female tissues 33 | 17,400
Nervous System 33 | 16,725
Blood and immune system 32 | 16,909
Cardiovascular System 32 | 15,192
Digestive Tract 32 | 17,369
Liver and Pancreas 32 | 16,750
Male tissues 32 | 17,142
Respiratory system 32 | 16,393
Skin and soft tissues 32 | 17,230
Urinary Tract 32 | 16,678

Target Family

Non-IDG 12 | 12,091
Transcription Factor 11 | 1,400
Epigenetic 8 | 242
Enzyme 2 | 4,145
TF/Epigenetic 1 | 38

GO Function

repressing transcription facto... 34 | 34
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone deacetylase 9 HDAC9 Tclin Epigenetic -2.27309 185.2 431
Sorcin SRI Tbio Non-IDG -2.69915 481.5 119
Transcription factor E2-alpha TCF3 Tbio Transcription Factor -2.80290 601.6 434
Runt-related transcription factor 2 RUNX2 Tbio Transcription Factor -3.40091 2392.3 631
Chromobox protein homolog 5 CBX5 Tbio Epigenetic -1.90801 83.4 624
Melanoma-associated antigen 2 MAGEA2 Tbio Non-IDG -1.32923 19.6 34
Zinc finger protein 703 ZNF703 Tbio Non-IDG -1.21377 18.7 190
Hematopoietically-expressed homeobox protein HHEX HHEX Tbio Transcription Factor -3.05655 1150.7 363
TATA-box-binding protein TBP Tbio Non-IDG -3.27246 1844.4 387
Protein/nucleic acid deglycase DJ-1 PARK7 Tbio Enzyme -2.89261 835.5 625