Development Level

Tbio 38 | 11,445
Tchem 6 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

enlarged heart 3 | 210
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
embryonic lethality prior to o... 2 | 239
increased mean corpuscular hem... 2 | 96
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal skin morphology 1 | 50
anophthalmia 1 | 33
decreased body weight 1 | 161
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased mean corpuscular hem... 1 | 50
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged uterus 1 | 11
hydrometra 1 | 53
hypoactivity 1 | 132
increased body length 1 | 32
increased circulating alkaline... 1 | 122
increased heart left ventricle... 1 | 4
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
male infertility 1 | 123
preweaning lethality, complete... 1 | 979
small kidney 1 | 16
small superior vagus ganglion 1 | 74

Disease

Carcinoma 33 | 11,493
ovarian cancer 27 | 8,520
medulloblastoma, large-cell 26 | 6,241
osteosarcoma 25 | 7,950
glioblastoma 22 | 5,792
lung cancer 21 | 4,740
atypical teratoid / rhabdoid tumor 18 | 5,112
psoriasis 18 | 6,694
Cancer 17 | 2,499
ependymoma 16 | 4,679
lung adenocarcinoma 15 | 2,716
oligodendroglioma 15 | 2,850
group 3 medulloblastoma 14 | 4,104
Astrocytoma, Pilocytic 13 | 3,081
Breast cancer 13 | 3,578
adult high grade glioma 13 | 3,801
astrocytic glioma 13 | 2,597
malignant mesothelioma 13 | 3,232
primitive neuroectodermal tumor 13 | 3,035
Kidney cancer 11 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
non-small cell lung cancer 11 | 2,890
subependymal giant cell astrocytoma 11 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
Pick disease 9 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
cystic fibrosis 8 | 1,696
diabetes mellitus 8 | 1,728
interstitial cystitis 8 | 2,312
invasive ductal carcinoma 8 | 2,951
pancreatic cancer 8 | 2,398
pituitary cancer 8 | 1,972
astrocytoma 7 | 1,146
breast carcinoma 7 | 1,638
group 4 medulloblastoma 7 | 1,855
ulcerative colitis 7 | 1,819
ductal carcinoma in situ 6 | 1,745
pediatric high grade glioma 6 | 1,064
Bipolar Disorder 5 | 666
Down syndrome 5 | 499
Multiple myeloma 5 | 1,332
Rheumatoid arthritis 5 | 1,191
Schizophrenia 5 | 1,160
adrenocortical carcinoma 5 | 1,428
dermatomyositis 5 | 966
lung carcinoma 5 | 2,843
nasopharyngeal carcinoma 5 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
spina bifida 5 | 1,074
Amyotrophic lateral sclerosis 4 | 451
Autosomal recessive predisposition 4 | 1,442
Blepharoptosis 4 | 231
Carcinoma, Squamous Cell 4 | 110
Endometriosis 4 | 540
Immune system cancer 4 | 140
Liver Cirrhosis, Experimental 4 | 769
Melanoma 4 | 711
Orbital separation excessive 4 | 244
Vascular disease 4 | 319
acute quadriplegic myopathy 4 | 1,158
hepatocellular carcinoma 4 | 547
pancreatic carcinoma 4 | 562
primary Sjogren syndrome 4 | 735
progressive supranuclear palsy 4 | 676
Adenocarcinoma 3 | 122
Breast Neoplasms 3 | 445
Cognitive delay 3 | 608
Crohn's disease 3 | 321
Downward slant of palpebral fissure 3 | 158
Dysarthria 3 | 192
Frontal bossing 3 | 157
Global developmental delay 3 | 608
Hemangiosarcoma 3 | 18
Hypertension 3 | 396
Liver cancer 3 | 604
Lung Neoplasms 3 | 232
Lymphoid leukemia 3 | 160
Mental and motor retardation 3 | 608
Mouth Neoplasms 3 | 55
Neurodegenerative disease 3 | 414
Prostatic Neoplasms 3 | 495
Skin cancer 3 | 469
Somatic mutation 3 | 61
Squamous cell carcinoma 3 | 129
Waldenstrons macroglobulinemia 3 | 765
acute myeloid leukemia 3 | 783
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
esophageal adenocarcinoma 3 | 737
nephrosclerosis 3 | 333
primary pancreatic ductal adenocarcinoma 3 | 1,109
tuberculosis 3 | 2,010
Adenoid Cystic Carcinoma 2 | 99
Carcinoma, Adenoid Cystic 2 | 99
Decreased tendon reflex 2 | 122
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Phenotypic variability 2 | 150
Progressive disorder 2 | 142

Tissue

Digestive Tract 45 | 17,369
Endocrine System 45 | 18,159
Female tissues 45 | 17,400
Liver and Pancreas 45 | 16,750
Male tissues 45 | 17,142
Nervous System 45 | 16,725
Respiratory system 45 | 16,393
Skin and soft tissues 45 | 17,230
Urinary Tract 45 | 16,678
Blood and immune system 44 | 16,909
Cardiovascular System 43 | 15,192

Target Family

Non-IDG 29 | 12,091
Enzyme 14 | 4,145
Transcription Factor 2 | 1,400

GO Function

receptor tyrosine kinase bindi... 45 | 45
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myocilin MYOC Tbio Non-IDG -2.65916 482.8 169
Membrane-associated phosphatidylinositol transfer protein 3 PITPNM3 Tbio Non-IDG -1.39360 23.8 107
Flt3-interacting zinc finger protein 1 FIZ1 Tdark Transcription Factor -0.28657 2.70 111
Copine-3 CPNE3 Tbio Non-IDG -0.95488 10.4 119
Suppressor of cytokine signaling 5 SOCS5 Tbio Non-IDG -2.04740 106.6 135
SHC-transforming protein 2 SHC2 Tbio Non-IDG -2.47843 293.4 113
14-3-3 protein gamma YWHAG Tbio Non-IDG -1.87443 78.9 387
SHC-transforming protein 3 SHC3 Tbio Non-IDG -1.97665 99.4 137
Fms-related tyrosine kinase 3 ligand FLT3LG Tbio Enzyme -2.31017 235.2 270
Hepatocyte growth factor-like protein MST1 Tbio Enzyme -2.04160 93.5 0