Development Level

Tchem 7 | 1,598

IMPC Phenotype

abnormal clavicle morphology 1 | 6
abnormal gait 1 | 69
cataract 1 | 92
decreased circulating glycerol... 1 | 16
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
increased circulating choleste... 1 | 66
increased total body fat amoun... 1 | 134

Disease

interstitial cystitis 5 | 2,312
osteosarcoma 4 | 7,950
psoriasis 4 | 6,694
Carcinoma 3 | 11,493
Epilepsy 3 | 792
Low compliance bladder 3 | 11
ulcerative colitis 3 | 1,819
Astrocytoma, Pilocytic 2 | 3,081
Chronic Lymphocytic Leukemia 2 | 262
Depressive disorder 2 | 409
Epilepsy, Temporal Lobe 2 | 23
Hyperalgesia 2 | 83
Major Depressive Disorder 2 | 301
Neurogenic bladder 2 | 16
atypical teratoid / rhabdoid tumor 2 | 5,112
cutaneous lupus erythematosus 2 | 1,057
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
non-small cell lung cancer 2 | 2,890
Arthritis 1 | 290
Arts syndrome 1 | 26
Autosomal recessive predisposition 1 | 1,442
BLEEDING DISORDER, PLATELET-TYPE, 8 1 | 2
Bipolar Disorder 1 | 666
Cancer 1 | 2,499
Cataract 3 multiple types 1 | 10
Congenital deafness 1 | 185
DEAFNESS, AUTOSOMAL DOMINANT 41 (disorder) 1 | 1
Deafness 1 | 198
Deafness, Autosomal Dominant 41 1 | 1
Disease Models, Animal 1 | 155
Ecchymosis 1 | 66
Epistaxis 1 | 43
Generalized anxiety disorder 1 | 29
Hearing Loss, Partial 1 | 185
Hearing loss, progressive sensorineural 1 | 23
Hypophosphatasia 1 | 10
Impaired ADP-induced platelet aggregation 1 | 1
Increased tendency to bruise 1 | 66
Irritable bowel syndrome 1 | 60
Leukemia, Lymphocytic, Chronic, B-Cell 1 | 34
Menopausal flushing 1 | 17
Mental Depression 1 | 333
Migraine 1 | 83
Mood Disorders 1 | 184
Multiple Sclerosis 1 | 540
Neurodegenerative disease 1 | 414
Neurotoxicity Syndromes 1 | 26
Nonsyndromic deafness 1 | 142
Pain agnosia 1 | 104
Pain disorder 1 | 15
Panic disorder 1 | 61
Persistent bleeding after trauma 1 | 6
Phaeochromocytoma 1 | 20
Pick disease 1 | 1,894
Posttraumatic stress disorder 1 | 2
Premenstrual dysphoric disorder 1 | 8
Prolonged bleeding after surgery 1 | 2
Radiation cystitis 1 | 1
Root resorption 1 | 22
Social phobia 1 | 10
Spinal Cord Injuries 1 | 8
Tinnitus 1 | 19
Trauma, Nervous System 1 | 2
Vascular disease 1 | 319
acute myeloid leukemia 1 | 783
astrocytic glioma 1 | 2,597
ependymoma 1 | 4,679
esophageal adenocarcinoma 1 | 737
facioscapulohumeral dystrophy 1 | 288
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
hearing impairment 1 | 199
invasive ductal carcinoma 1 | 2,951
lung cancer 1 | 4,740
lung carcinoma 1 | 2,843
malignant mesothelioma 1 | 3,232
medulloblastoma, large-cell 1 | 6,241
nasopharyngeal carcinoma 1 | 1,058
obsessive-compulsive disorder 1 | 61
oligodendroglioma 1 | 2,850
ovarian cancer 1 | 8,520
pancreatic cancer 1 | 2,398
platelet-type bleeding disorder 8 1 | 3
primary Sjogren syndrome 1 | 735
primary pancreatic ductal adenocarcinoma 1 | 1,109
progressive supranuclear palsy 1 | 676
tuberculosis 1 | 2,010

Tissue

Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Skin and soft tissues 7 | 17,230
Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Respiratory system 6 | 16,393
Urinary Tract 6 | 16,678

Target Family

Ion Channel 7 | 344

GO Function

purinergic nucleotide receptor... 7 | 7
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
P2X purinoceptor 3 P2RX3 Tchem Ion Channel -2.55623 360.2 162
P2X purinoceptor 7 P2RX7 Tchem Ion Channel -2.96940 962.2 272
P2X purinoceptor 6 P2RX6 Tchem Ion Channel -1.46307 26.2 147
P2X purinoceptor 5 P2RX5 Tchem Ion Channel -1.56458 35.6 136
P2X purinoceptor 1 P2RX1 Tchem Ion Channel -2.41145 259.4 137
P2X purinoceptor 4 P2RX4 Tchem Ion Channel -2.49038 314.8 181
P2X purinoceptor 2 P2RX2 Tchem Ion Channel -2.49038 300.7 245