Development Level

Tbio 2 | 11,445

IMPC Phenotype

increased startle reflex 1 | 112

Disease

adult high grade glioma 2 | 3,801
atypical teratoid / rhabdoid tumor 2 | 5,112
glioblastoma 2 | 5,792
lung cancer 2 | 4,740
medulloblastoma, large-cell 2 | 6,241
ovarian cancer 2 | 8,520
Absent speech 1 | 43
Astrocytoma, Pilocytic 1 | 3,081
Bacterial conjunctivitis 1 | 10
Bladder neck obstruction 1 | 4
Breast Neoplasms 1 | 445
Bulging forehead 1 | 66
Byzanthine arch palate 1 | 194
CNS hypomyelination 1 | 17
Carcinoma 1 | 11,493
Chronic Lymphocytic Leukemia 1 | 262
Cognitive delay 1 | 608
Delayed myelination 1 | 22
Duchenne muscular dystrophy 1 | 601
Dull intelligence 1 | 645
Epilepsy 1 | 792
Feeding difficulties 1 | 127
Global developmental delay 1 | 608
Highly variable severity 1 | 157
Hypomyelination 1 | 17
Intellectual disability 1 | 1,016
Low intelligence 1 | 645
MENTAL RETARDATION, AUTOSOMAL DOMINANT 31 1 | 1
Mammary Neoplasms 1 | 425
Mental Retardation 1 | 645
Mental and motor retardation 1 | 608
Mental deficiency 1 | 645
Muscle hypotonia 1 | 571
Myoclonus 1 | 74
Myopathic facies 1 | 13
Neonatal Hypotonia 1 | 64
Nystagmus 1 | 317
Open mouth 1 | 45
Poor school performance 1 | 645
Progressive multifocal leukoencephalopathy 1 | 25
Prominent forehead 1 | 66
Relapsing fever 1 | 14
Respiratory Insufficiency 1 | 132
Respiratory function loss 1 | 121
Seizures 1 | 596
Strabismus 1 | 270
Variable expressivity 1 | 157
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
aldosterone-producing adenoma 1 | 665
astrocytoma 1 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
cystic fibrosis 1 | 1,696
dermatomyositis 1 | 966
ependymoma 1 | 4,679
gastric carcinoma 1 | 807
group 3 medulloblastoma 1 | 4,104
hepatocellular carcinoma 1 | 547
interstitial cystitis 1 | 2,312
invasive ductal carcinoma 1 | 2,951
juvenile dermatomyositis 1 | 1,187
medulloblastoma 1 | 720
nasopharyngeal carcinoma 1 | 1,058
nephrosclerosis 1 | 333
nonverbal 1 | 43
osteosarcoma 1 | 7,950
pancreatic cancer 1 | 2,398
primary Sjogren syndrome 1 | 735
primary pancreatic ductal adenocarcinoma 1 | 1,109
primitive neuroectodermal tumor 1 | 3,035
psoriasis 1 | 6,694
tuberculosis 1 | 2,010

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Non-IDG 1 | 12,091
Transcription Factor 1 | 1,400

GO Function

purine-rich negative regulator... 2 | 2
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ETS domain-containing protein Elk-3 ELK3 Tbio Transcription Factor -0.17124 0.86 225
Transcriptional activator protein Pur-alpha PURA Tbio Non-IDG -2.17708 158.7 170