Development Level

Tbio 7 | 11,445
Tchem 4 | 1,598

IMPC Phenotype

increased bone mineral content 2 | 108
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
decreased circulating insulin ... 1 | 76
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
enlarged heart 1 | 210
increased bone mineral density 1 | 72
short tibia 1 | 97
small superior vagus ganglion 1 | 74

Disease

Carcinoma 10 | 11,493
glioblastoma 9 | 5,792
ovarian cancer 9 | 8,520
osteosarcoma 8 | 7,950
Cancer 7 | 2,499
invasive ductal carcinoma 7 | 2,951
psoriasis 7 | 6,694
Breast cancer 6 | 3,578
cystic fibrosis 6 | 1,696
diabetes mellitus 6 | 1,728
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung cancer 6 | 4,740
medulloblastoma, large-cell 6 | 6,241
pancreatic cancer 6 | 2,398
Astrocytoma, Pilocytic 5 | 3,081
Duchenne muscular dystrophy 5 | 601
Kidney cancer 5 | 2,613
gastric carcinoma 5 | 807
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung carcinoma 5 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
tuberculosis 5 | 2,010
Arthritis 4 | 290
Chronic hepatitis C 4 | 12
adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
cutaneous lupus erythematosus 4 | 1,057
malignant mesothelioma 4 | 3,232
pituitary cancer 4 | 1,972
ulcerative colitis 4 | 1,819
Kidney disease 3 | 430
Liver Cirrhosis, Experimental 3 | 769
Melanoma 3 | 711
Skin cancer 3 | 469
Vascular disease 3 | 319
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
astrocytoma 3 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
breast carcinoma 3 | 1,638
ependymoma 3 | 4,679
esophageal adenocarcinoma 3 | 737
juvenile dermatomyositis 3 | 1,187
mucosa-associated lymphoid tissue lymphoma 3 | 484
nasopharyngeal carcinoma 3 | 1,058
non-small cell lung cancer 3 | 2,890
periodontitis 3 | 293
primary Sjogren syndrome 3 | 735
primary pancreatic ductal adenocarcinoma 3 | 1,109
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
Acquired scoliosis 2 | 281
Alzheimer's disease 2 | 658
Atopic dermatitis 2 | 952
Autosomal recessive predisposition 2 | 1,442
Becker muscular dystrophy 2 | 191
Blue sclera 2 | 32
Curvature of spine 2 | 282
Dementia 2 | 175
Dental caries 2 | 164
Ehlers-Danlos syndrome 2 | 43
Exophthalmos 2 | 112
Fascioliasis 2 | 17
Heart disease 2 | 306
Liver cancer 2 | 604
Neoplasm Invasiveness 2 | 161
Obesity 2 | 678
Osteoporosis 2 | 363
Pick disease 2 | 1,894
Polycystic ovary syndrome 2 | 360
Prominent eyes 2 | 96
Prominent globes 2 | 96
Proteinuria 2 | 144
Protruding eyes 2 | 96
Pycnodysostosis 2 | 5
Rotting teeth 2 | 73
Schizophrenia 2 | 1,160
Short stature 2 | 531
Sleeping sickness 2 | 37
X-linked cerebral adrenoleukodystrophy 2 | 116
active Crohn's disease 2 | 922
adrenocortical adenoma 2 | 131
aldosterone-producing adenoma 2 | 665
colon cancer 2 | 1,478
dermatomyositis 2 | 966
head and neck cancer 2 | 271
lung adenocarcinoma 2 | 2,716
nephrosclerosis 2 | 333
oligodendroglioma 2 | 2,850
Alport syndrome 1 | 21
Diabetic retinopathy 1 | 56
Fragile skin 1 | 18
Pulmonary valve stenosis 1 | 9
Short distal phalanges 1 | 50
Small Cell Lung Carcinoma 1 | 41
Small cell carcinoma of lung 1 | 45
Varicosity 1 | 12

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Non-IDG 6 | 12,091
Enzyme 5 | 4,145

GO Function

proteoglycan binding 11 | 11
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenosine deaminase 2 ADA2 Tbio Enzyme -1.43407 32.5 98
Collagen alpha-3(V) chain COL5A3 Tbio Non-IDG -0.80962 6.18 73
Nidogen-1 NID1 Tbio Non-IDG -2.80605 647.4 267
Ficolin-2 FCN2 Tbio Non-IDG -2.26890 207.9 136
Cathepsin S CTSS Tchem Enzyme -3.31099 1955.9 291
Cathepsin B CTSB Tchem Enzyme -3.72723 5011.5 448
Slit homolog 2 protein SLIT2 Tbio Non-IDG -2.01765 104.0 215
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
Collagen alpha-1(V) chain COL5A1 Tbio Non-IDG -2.07285 114.2 274
Cathepsin L1 CTSL Tchem Enzyme -3.39489 2387.3 416