Development Level

Tbio 30 | 11,445
Tchem 5 | 1,598
Tdark 4 | 6,588

IMPC Phenotype

decreased lean body mass 2 | 135
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal humerus morphology 1 | 11
abnormal locomotor behavior 1 | 24
abnormal testis morphology 1 | 43
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating magnesiu... 1 | 13
decreased circulating total pr... 1 | 49
decreased cornea thickness 1 | 2
decreased grip strength 1 | 116
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
female infertility 1 | 60
increased lean body mass 1 | 172
male infertility 1 | 123
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
small testis 1 | 58

Disease

Carcinoma 20 | 11,493
ovarian cancer 18 | 8,520
osteosarcoma 16 | 7,950
psoriasis 14 | 6,694
glioblastoma 13 | 5,792
lung cancer 12 | 4,740
medulloblastoma, large-cell 12 | 6,241
ependymoma 11 | 4,679
atypical teratoid / rhabdoid tumor 10 | 5,112
malignant mesothelioma 10 | 3,232
Breast cancer 9 | 3,578
group 4 medulloblastoma 9 | 1,855
adult high grade glioma 8 | 3,801
astrocytic glioma 7 | 2,597
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung adenocarcinoma 7 | 2,716
pancreatic cancer 7 | 2,398
primitive neuroectodermal tumor 7 | 3,035
Cancer 6 | 2,499
Kidney cancer 6 | 2,613
invasive ductal carcinoma 6 | 2,951
non-small cell lung cancer 6 | 2,890
oligodendroglioma 6 | 2,850
ulcerative colitis 6 | 1,819
Endometriosis 5 | 540
Pick disease 5 | 1,894
acute quadriplegic myopathy 5 | 1,158
breast carcinoma 5 | 1,638
gastric cancer 5 | 459
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung carcinoma 5 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Astrocytoma, Pilocytic 4 | 3,081
Autosomal recessive predisposition 4 | 1,442
Duchenne muscular dystrophy 4 | 601
Multiple myeloma 4 | 1,332
adrenocortical carcinoma 4 | 1,428
astrocytoma 4 | 1,146
colon cancer 4 | 1,478
dermatomyositis 4 | 966
diabetes mellitus 4 | 1,728
hepatocellular carcinoma 4 | 547
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
juvenile dermatomyositis 4 | 1,187
non primary Sjogren syndrome sicca 4 | 891
pancreatic carcinoma 4 | 562
pituitary cancer 4 | 1,972
tuberculosis 4 | 2,010
urothelial carcinoma 4 | 318
Acquired scoliosis 3 | 281
Centronuclear myopathy 3 | 27
Curvature of spine 3 | 282
Endometrial cancer 3 | 311
Neurodegenerative disease 3 | 414
Rheumatoid arthritis 3 | 1,191
Vaccinia 3 | 36
Waldenstrons macroglobulinemia 3 | 765
cutaneous lupus erythematosus 3 | 1,057
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
pediatric high grade glioma 3 | 1,064
posterior fossa group B ependymoma 3 | 416
progressive supranuclear palsy 3 | 676
Acquired metabolic disease 2 | 336
Alzheimer's disease 2 | 658
Asthma 2 | 385
Charcot-Marie-Tooth disease 2 | 62
Decreased bone mineral density Z score 2 | 31
Depressive disorder 2 | 409
Distal sensory impairment 2 | 52
Down syndrome 2 | 499
Epilepsy 2 | 792
Hypertension 2 | 396
Hypertensive disease 2 | 292
Liver Cirrhosis, Experimental 2 | 769
Liver cancer 2 | 604
Liver carcinoma 2 | 240
Melanoma 2 | 711
Mental Depression 2 | 333
Myocardial Ischemia 2 | 169
Neuropathy 2 | 261
Obesity 2 | 678
Parkinson's disease 2 | 392
Schizophrenia 2 | 1,160
Skin cancer 2 | 469
Vascular disease 2 | 319
aldosterone-producing adenoma 2 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
chronic lymphosyte leukemia 2 | 204
chronic rhinosinusitis 2 | 512
cystic fibrosis 2 | 1,696
gastric carcinoma 2 | 807
hereditary spastic paraplegia 2 | 318
interstitial lung disease 2 | 298
limb girdle muscular dystrophy 2A 2 | 213
nasopharyngeal carcinoma 2 | 1,058
primary pancreatic ductal adenocarcinoma 2 | 1,109
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Endocrine System 37 | 18,159
Female tissues 37 | 17,400
Digestive Tract 36 | 17,369
Male tissues 36 | 17,142
Blood and immune system 35 | 16,909
Nervous System 35 | 16,725
Skin and soft tissues 35 | 17,230
Cardiovascular System 34 | 15,192
Liver and Pancreas 33 | 16,750
Respiratory system 32 | 16,393
Urinary Tract 32 | 16,678

Target Family

Enzyme 36 | 4,145
Non-IDG 3 | 12,091

GO Function

protein tyrosine-serine-threon... 39 | 39
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine/tyrosine-interacting-like protein 1 STYXL1 Tbio Enzyme -0.71996 6.79 40
Dual specificity protein phosphatase 26 DUSP26 Tbio Enzyme -2.81752 661.7 128
Dual specificity protein phosphatase CDC14C CDC14C Tdark Enzyme -0.37414 4.05 0
Dual specificity protein phosphatase 9 DUSP9 Tbio Enzyme -1.15238 17.2 202
Dual specificity protein phosphatase 13 isoform B DUSP13 Tbio Enzyme -1.26330 34.4 180
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 PTPMT1 Tbio Enzyme -1.36243 23.0 109
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
Dual specificity protein phosphatase 18 DUSP18 Tbio Enzyme -0.69461 5.47 26
Dual specificity phosphatase DUPD1 DUPD1 Tbio Enzyme -0.43334 2.53 42
Dual specificity protein phosphatase 12 DUSP12 Tbio Enzyme -1.78052 60.2 167