Development Level

Tbio 56 | 10,625
Tchem 21 | 1,890
Tdark 11 | 7,003

IMPC Term

preweaning lethality, complete... 4 | 633
abnormal sleep behavior 3 | 63
abnormal embryo size 2 | 112
decreased body length 2 | 108
decreased lean body mass 2 | 195
decreased total body fat amoun... 2 | 186
embryonic lethality prior to o... 2 | 148
increased heart weight 2 | 37
increased lean body mass 2 | 107
increased total body fat amoun... 2 | 57
abnormal bone structure 1 | 131
abnormal coat appearance 1 | 25
abnormal coat/hair pigmentatio... 1 | 54
abnormal humerus morphology 1 | 11
abnormal lens morphology 1 | 73
abnormal posture 1 | 5
abnormal retinal outer nuclear... 1 | 5
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 30
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased caudal vertebrae num... 1 | 49
decreased circulating LDL chol... 1 | 37
decreased circulating alkaline... 1 | 41
decreased circulating creatini... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating magnesiu... 1 | 11
decreased circulating potassiu... 1 | 17
decreased circulating sodium l... 1 | 18
decreased circulating total pr... 1 | 41
decreased cornea thickness 1 | 2
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased rib number 1 | 59
decreased thoracic vertebrae n... 1 | 7
decreased total retina thickne... 1 | 20
dilated heart left ventricle 1 | 10
female infertility 1 | 34
hydrops fetalis 1 | 22
hyperactivity 1 | 108
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased circulating sodium l... 1 | 71
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
increased or absent threshold ... 1 | 128
increased prepulse inhibition 1 | 21
increased sacral vertebrae num... 1 | 62
increased vertical activity 1 | 18
limb grasping 1 | 35
male infertility 1 | 62
persistence of hyaloid vascula... 1 | 22
preweaning lethality, incomple... 1 | 260
small adrenal glands 1 | 15
small testis 1 | 37

Disease

ovarian cancer 41 | 8,484
osteosarcoma 39 | 7,933
medulloblastoma, large-cell 36 | 6,234
glioblastoma 32 | 5,572
psoriasis 31 | 6,685
lung cancer 29 | 4,466
atypical teratoid / rhabdoid tumor 23 | 4,369
malignant mesothelioma 22 | 3,162
interstitial cystitis 20 | 2,299
non-small cell lung cancer 20 | 2,798
oligodendroglioma 20 | 2,849
ulcerative colitis 20 | 2,087
astrocytic glioma 19 | 2,241
ependymoma 18 | 2,514
Breast cancer 17 | 3,094
Carcinoma 17 | 2,147
primitive neuroectodermal tumor 17 | 3,031
pediatric high grade glioma 16 | 2,712
Pick disease 15 | 1,893
group 3 medulloblastoma 15 | 2,254
pilocytic astrocytoma 15 | 3,086
Cancer 14 | 2,346
group 4 medulloblastoma 14 | 1,875
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,289
invasive ductal carcinoma 14 | 2,950
lung carcinoma 14 | 2,844
adult high grade glioma 13 | 2,148
lung adenocarcinoma 13 | 2,713
pituitary cancer 13 | 1,972
colon cancer 12 | 1,475
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,988
subependymal giant cell astrocytoma 12 | 2,287
acute quadriplegic myopathy 11 | 1,157
breast carcinoma 11 | 1,614
posterior fossa group B ependymoma 11 | 1,530
cystic fibrosis 10 | 1,665
medulloblastoma 10 | 1,524
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,795
spina bifida 10 | 1,064
cutaneous lupus erythematosus 9 | 1,056
dermatomyositis 9 | 933
diabetes mellitus 9 | 1,663
ductal carcinoma in situ 9 | 1,745
pancreatic cancer 9 | 2,300
adrenocortical carcinoma 8 | 1,427
astrocytoma 8 | 1,493
esophageal adenocarcinoma 8 | 737
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
juvenile dermatomyositis 8 | 1,189
sonic hedgehog group medulloblastoma 8 | 1,482
tuberculosis 8 | 1,557
Centronuclear myopathy 7 | 21
IGA Glomerulonephritis 7 | 454
aldosterone-producing adenoma 7 | 664
gastric carcinoma 7 | 832
non primary Sjogren syndrome sicca 7 | 840
progressive supranuclear palsy 7 | 674
Duchenne muscular dystrophy 6 | 602
Rheumatoid Arthritis 6 | 1,160
active Crohn's disease 6 | 918
posterior fossa group A ependymoma 6 | 1,511
Crohn's disease 5 | 304
Endometriosis 5 | 535
Multiple myeloma 5 | 1,327
urothelial carcinoma 5 | 318
Atopic dermatitis 4 | 944
Chronic Lymphocytic Leukemia 4 | 242
Nonsyndromic deafness 4 | 121
Waldenstrons macroglobulinemia 4 | 765
atypical teratoid/rhabdoid tumor 4 | 1,095
hepatocellular carcinoma 4 | 532
inflammatory breast cancer 4 | 404
nasopharyngeal carcinoma 4 | 1,056
primary Sjogren syndrome 4 | 789
tuberculosis and treatment for 6 months 4 | 686
Acquired metabolic disease 3 | 267
Alzheimer's disease 3 | 644
Amyotrophic Lateral Sclerosis 3 | 431
Barrett's esophagus 3 | 183
Celiac disease 3 | 112
Inflammatory Bowel Diseases 3 | 87
Kidney disease 3 | 396
Melanoma 3 | 261
Multiple Sclerosis 3 | 498
Neurodegenerative disease 3 | 383
Parkinson's disease 3 | 364
Peripheral Neuropathy 3 | 303
Schizophrenia 3 | 501
Vaccinia 3 | 37
active ulcerative colitis 3 | 477
acute myeloid leukemia 3 | 780
chronic lymphosyte leukemia 3 | 232
chronic rhinosinusitis 3 | 512
fibroadenoma 3 | 557
gastric cancer 3 | 430
glioblastoma multiforme 3 | 347
hereditary spastic paraplegia 3 | 313
mucosa-associated lymphoid tissue lymphoma 3 | 480
pancreatic carcinoma 3 | 567
primary pancreatic ductal adenocarcinoma 3 | 1,271

Tissue

Blood and immune system 85 | 17,995
Nervous System 85 | 18,561
Urinary Tract 85 | 18,444
Cardiovascular System 84 | 17,958
Digestive Tract 84 | 18,473
Endocrine System 84 | 18,512
Liver and Pancreas 84 | 18,136
Male tissues 84 | 17,969
Female tissues 83 | 18,647
Skin and soft tissues 83 | 18,115
Respiratory system 82 | 17,484

Target Family

Enzyme 81 | 4,146
Non-IDG 7 | 11,971

GO Function

protein tyrosine phosphatase a... 88 | 88
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein phosphatase non-receptor type 13 PTPN13 Tchem Enzyme -2.20613 177.9 120
Receptor-type tyrosine-protein phosphatase eta PTPRJ Tbio Enzyme -1.94494 110.6 235
Dual specificity protein phosphatase 18 DUSP18 Tbio Enzyme -0.67210 5.47 19
Protein phosphatase Slingshot homolog 1 SSH1 Tbio Enzyme -1.41770 25.0 106
Dual specificity protein phosphatase 23 DUSP23 Tbio Enzyme -0.95604 11.5 79
Protein phosphatase Slingshot homolog 2 SSH2 Tchem Enzyme -0.70039 3.84 25
Tyrosine-protein phosphatase non-receptor type 11 PTPN11 Tchem Enzyme -3.06784 1308.8 971
Tyrosine-protein phosphatase non-receptor type 7 PTPN7 Tchem Enzyme -1.49914 33.9 204
Putative tyrosine-protein phosphatase auxilin DNAJC6 Tbio Enzyme -1.67985 56.6 79
Dual specificity protein phosphatase 10 DUSP10 Tbio Enzyme -1.44184 35.9 248