Development Level

Tbio 6 | 11,445
Tdark 2 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

abnormal locomotor behavior 1 | 24
decreased caudal vertebrae num... 1 | 53
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
impaired glucose tolerance 1 | 75
increased prepulse inhibition 1 | 32
preweaning lethality, complete... 1 | 979

Disease

medulloblastoma, large-cell 7 | 6,241
ovarian cancer 7 | 8,520
glioblastoma 5 | 5,792
Carcinoma 4 | 11,493
group 3 medulloblastoma 4 | 4,104
osteosarcoma 4 | 7,950
Breast cancer 3 | 3,578
Cancer 3 | 2,499
Pick disease 3 | 1,894
astrocytic glioma 3 | 2,597
atypical teratoid / rhabdoid tumor 3 | 5,112
ependymoma 3 | 4,679
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
psoriasis 3 | 6,694
Acquired metabolic disease 2 | 336
Astrocytoma, Pilocytic 2 | 3,081
Kidney cancer 2 | 2,613
Multiple myeloma 2 | 1,332
Rheumatoid arthritis 2 | 1,191
acute myeloid leukemia 2 | 783
aldosterone-producing adenoma 2 | 665
astrocytoma 2 | 1,146
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
lung carcinoma 2 | 2,843
non primary Sjogren syndrome sicca 2 | 891
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Alpha thalassemia-X-linked intellectual disability syndrome 1 | 3
Alzheimer's disease 1 | 658
Arthritis, Rheumatoid 1 | 174
Autosomal recessive nonsyndromic deafness 26 1 | 3
Bipolar Disorder 1 | 666
Cafe-au-Lait Spots 1 | 37
Cardiofaciocutaneous syndrome 1 | 15
Congenital neurologic anomalies 1 | 20
Costello Syndrome 1 | 17
Craniofacial Abnormalities 1 | 151
Crohn's disease 1 | 321
Dyschromatosis universalis hereditaria 1 | 6
Gingival fibromatosis 1 | 14
Globe disease 1 | 67
Glomerulonephritis, IGA 1 | 34
Hereditary Motor and Sensory-Neuropathy Type II 1 | 4
Hereditary sensory and autonomic neuropathy type 2 1 | 4
Hypersensitivity reaction type II disease 1 | 253
Hypertension 1 | 396
IgA NEPHROPATHY, SUSCEPTIBILITY TO, 3 1 | 1
Kidney Diseases 1 | 114
Kidney disease 1 | 430
LEOPARD syndrome 1 | 20
Lung Neoplasms 1 | 232
Lung diseases 1 | 50
Mental Depression 1 | 333
Metabolic acidosis 1 | 90
Multiple Sclerosis 1 | 540
NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IIA 1 | 4
Nervous System Malformations 1 | 10
Neurodegenerative disease 1 | 414
Neurofibromatosis 1 | 40
Neuropathy 1 | 261
Neuropathy, Hereditary Sensory and Autonomic, Type 2A 1 | 4
Nonsyndromic deafness 1 | 142
Noonan syndrome 1 | 34
Optic disk drusen 1 | 4
Orofacial cleft 1 | 54
Piebaldism 1 | 15
Polycystic ovary syndrome 1 | 360
Pseudohypoaldosteronism 1 | 23
Pseudohypoaldosteronism, type 2 1 | 4
Pulmonary valve stenosis 1 | 9
Retinitis pigmentosa 28 1 | 19
Tobacco Use Disorder 1 | 12
Type 2 diabetes mellitus 1 | 272
Usher syndrome 1 | 32
Waldenstrons macroglobulinemia 1 | 765
active ulcerative colitis 1 | 764
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
adult high grade glioma 1 | 3,801
breast carcinoma 1 | 1,638
cystic fibrosis 1 | 1,696
diabetes mellitus 1 | 1,728
interstitial lung disease 1 | 298
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
nasopharyngeal carcinoma 1 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
posterior fossa group B ependymoma 1 | 416
progressive supranuclear palsy 1 | 676
sarcoidosis 1 | 370
tuberculosis and treatment for 3 months 1 | 179

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Non-IDG 8 | 12,091
Kinase 1 | 634

GO Function

protein serine-threonine kinas... 9 | 9
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.08897 121.1 264
Serine/threonine-protein kinase WNK1 WNK1 Tchem Kinase -2.79557 617.6 414
Sprouty-related, EVH1 domain-containing protein 1 SPRED1 Tbio Non-IDG -1.93963 79.1 299
Core histone macro-H2A.1 H2AFY Tbio Non-IDG -1.78572 69.6 95
PAK4-inhibitor INKA1 FAM212A Tdark Non-IDG -0.27984 2.18 62
PAK4-inhibitor INKA2 FAM212B Tdark Non-IDG 0.00000 91
Protein sprouty homolog 2 SPRY2 Tbio Non-IDG -1.90829 87.6 217
Sprouty-related, EVH1 domain-containing protein 2 SPRED2 Tbio Non-IDG -1.13996 20.0 106
Regulatory-associated protein of mTOR RPTOR Tbio Non-IDG -2.83172 622.9 461