Development Level

Tbio 16 | 11,445
Tdark 12 | 6,588
Tchem 1 | 1,598

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

abnormal behavior 4 | 298
hyperactivity 3 | 148
abnormal sleep behavior 2 | 70
decreased circulating triglyce... 2 | 79
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal forebrain development 1 | 20
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal midbrain development 1 | 20
abnormal spinal cord morpholog... 1 | 9
abnormal tail bud morphology 1 | 8
abnormal vocalization 1 | 21
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 101
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased coping response 1 | 4
increased exploration in new e... 1 | 8
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased vertical activity 1 | 24
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 14 | 11,493
osteosarcoma 12 | 7,950
ovarian cancer 12 | 8,520
glioblastoma 11 | 5,792
medulloblastoma, large-cell 11 | 6,241
atypical teratoid / rhabdoid tumor 10 | 5,112
lung cancer 9 | 4,740
psoriasis 9 | 6,694
adult high grade glioma 8 | 3,801
group 3 medulloblastoma 8 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
primitive neuroectodermal tumor 8 | 3,035
ependymoma 7 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
subependymal giant cell astrocytoma 7 | 2,287
malignant mesothelioma 6 | 3,232
Astrocytoma, Pilocytic 5 | 3,081
Breast cancer 5 | 3,578
Cancer 5 | 2,499
lung adenocarcinoma 5 | 2,716
oligodendroglioma 5 | 2,850
Multiple myeloma 4 | 1,332
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
group 4 medulloblastoma 4 | 1,855
lung carcinoma 4 | 2,843
medulloblastoma 4 | 720
tuberculosis 4 | 2,010
Pick disease 3 | 1,894
Schizophrenia 3 | 1,160
astrocytoma 3 | 1,146
diabetes mellitus 3 | 1,728
invasive ductal carcinoma 3 | 2,951
non-small cell lung cancer 3 | 2,890
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
posterior fossa group A ependymoma 3 | 468
posterior fossa group B ependymoma 3 | 416
ulcerative colitis 3 | 1,819
Congenital stationary night blindness 2 | 29
Crohn's disease 2 | 321
Kidney cancer 2 | 2,613
Parkinson's disease 2 | 392
Prostate cancer 2 | 175
Rheumatoid arthritis 2 | 1,191
Waldenstrons macroglobulinemia 2 | 765
aldosterone-producing adenoma 2 | 665
colon cancer 2 | 1,478
ductal carcinoma in situ 2 | 1,745
hepatocellular carcinoma 2 | 547
hereditary spastic paraplegia 2 | 318
interstitial cystitis 2 | 2,312
juvenile dermatomyositis 2 | 1,187
nasopharyngeal carcinoma 2 | 1,058
non primary Sjogren syndrome sicca 2 | 891
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074
Abnormality of retinal pigmentation 1 | 111
Abnormality of the retinal vasculature 1 | 59
Animal Mammary Neoplasms 1 | 136
Atypical scarring of skin 1 | 62
Barrett's esophagus 1 | 182
Blind Vision 1 | 111
Blindness, Legal 1 | 110
Cardiomegaly 1 | 116
Chorioretinal atrophy 1 | 11
Colorectal Neoplasms 1 | 243
Conductive hearing loss 1 | 123
Congenital anomaly of testis 1 | 52
DOID:3363 1 | 3
Difficulties with night vision 1 | 87
Hemeralopia 1 | 4
Hyperinsulinism 1 | 133
Impotence 1 | 42
Keratoconus 1 | 113
Liver disease 1 | 237
Low Vision 1 | 174
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Mesothelioma 1 | 38
Myocardial Infarction 1 | 151
Necrosis 1 | 53
Night Blindness 1 | 101
Night blindness, progressive 1 | 51
Ophthalmoplegia 1 | 106
Osteoporosis 1 | 363
Pain agnosia 1 | 104
Pain disorder 1 | 15
Photodysphoria 1 | 121
Photophobia 1 | 121
Pigmentary retinal degeneration 1 | 11
Retinal Degeneration 1 | 106
Retinal exudates 1 | 11
Retinal pigment epithelial abnormality 1 | 111
Sensorineural Hearing Loss (disorder) 1 | 284
Skin atrophy 1 | 16
Tinea corporis 1 | 25
Visual Impairment 1 | 174
permanent atrial fibrillation 1 | 45

Tissue

Endocrine System 27 | 18,159
Female tissues 26 | 17,400
Male tissues 26 | 17,142
Blood and immune system 25 | 16,909
Digestive Tract 25 | 17,369
Liver and Pancreas 25 | 16,750
Nervous System 25 | 16,725
Respiratory system 25 | 16,393
Skin and soft tissues 25 | 17,230
Urinary Tract 24 | 16,678
Cardiovascular System 23 | 15,192

Target Family

Enzyme 20 | 4,145
Non-IDG 8 | 12,091
Kinase 1 | 634

GO Function

protein phosphatase inhibitor ... 29 | 29
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Putative protein phosphatase inhibitor 2-like protein 1 PPP1R2P1 Tdark Enzyme 0.00000 0
Protein phosphatase 1 regulatory subunit 27 PPP1R27 Tdark Enzyme -0.03779 1.08 82
Serine/threonine-protein phosphatase 1 regulatory subunit 10 PPP1R10 Tbio Enzyme -1.71843 50.9 110
Unconventional prefoldin RPB5 interactor 1 URI1 Tbio Enzyme -2.15409 134.8 150
Serine/threonine-protein kinase LMTK2 LMTK2 Tbio Kinase -1.46351 31.6 189
Neurabin-2 PPP1R9B Tdark Non-IDG 0.00000 0
Protein phosphatase 1 regulatory subunit 37 PPP1R37 Tdark Enzyme 0.00000 46
Protein phosphatase 1 regulatory subunit 14B PPP1R14B Tbio Enzyme -1.24613 17.6 30
Pleiotrophin PTN Tbio Non-IDG -2.85163 746.7 392
Protein phosphatase inhibitor 2-like protein 3 PPP1R2B Tdark Enzyme -1.20523 26.2 0