Development Level

Tbio 14 | 11,445
Tchem 9 | 1,598
Tclin 4 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal behavior 2 | 298
abnormal bone structure 1 | 187
abnormal epididymis morphology 1 | 42
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating glucose ... 1 | 126
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
edema 1 | 59
hemorrhage 1 | 23
hypoactivity 1 | 132
increased cardiac muscle contr... 1 | 8
increased circulating sodium l... 1 | 71
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
polycystic kidney 1 | 15
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 20 | 11,493
ovarian cancer 19 | 8,520
osteosarcoma 16 | 7,950
psoriasis 13 | 6,694
Cancer 12 | 2,499
glioblastoma 11 | 5,792
medulloblastoma, large-cell 11 | 6,241
Breast cancer 9 | 3,578
atypical teratoid / rhabdoid tumor 9 | 5,112
ependymoma 9 | 4,679
group 3 medulloblastoma 9 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
lung cancer 9 | 4,740
diabetes mellitus 8 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
adult high grade glioma 7 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
malignant mesothelioma 7 | 3,232
primitive neuroectodermal tumor 7 | 3,035
Astrocytoma, Pilocytic 6 | 3,081
Bipolar Disorder 6 | 666
Obesity 6 | 678
Schizophrenia 6 | 1,160
astrocytic glioma 6 | 2,597
pancreatic cancer 6 | 2,398
tuberculosis 6 | 2,010
Alzheimer's disease 5 | 658
Kidney cancer 5 | 2,613
Parkinson's disease 5 | 392
Pick disease 5 | 1,894
Toxic encephalopathy 5 | 141
ductal carcinoma in situ 5 | 1,745
oligodendroglioma 5 | 2,850
Brain disease 4 | 96
Breast Neoplasms 4 | 445
Depressive disorder 4 | 409
Hypertension 4 | 396
Lung Neoplasms 4 | 232
Mammary Neoplasms 4 | 425
Prostatic Neoplasms 4 | 495
Splenomegaly 4 | 190
Vascular disease 4 | 319
primary pancreatic ductal adenocarcinoma 4 | 1,109
spina bifida 4 | 1,074
Adenoma 3 | 167
Autosomal recessive predisposition 3 | 1,442
Carcinoma, Hepatocellular 3 | 228
Cell Transformation, Neoplastic 3 | 97
Cognitive delay 3 | 608
Colorectal Neoplasms 3 | 243
Epilepsy 3 | 792
Fatty liver disease 3 | 103
Global developmental delay 3 | 608
Hemangioma 3 | 69
Hyperglycemia 3 | 137
Hyperinsulinism 3 | 133
Hypertensive disease 3 | 292
Inflammation 3 | 120
Leukemia, Myelocytic, Acute 3 | 120
Leukemia, Myeloid, Acute 3 | 105
Liver Cirrhosis, Experimental 3 | 769
Liver carcinoma 3 | 240
Memory Disorders 3 | 40
Mental and motor retardation 3 | 608
Multiple myeloma 3 | 1,332
Muscular atrophy 3 | 71
Myocardial Infarction 3 | 151
Neoplastic Cell Transformation 3 | 89
Neurodegenerative disease 3 | 414
Seizures 3 | 596
Skin cancer 3 | 469
Stomach Neoplasms 3 | 300
Weight decreased 3 | 103
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
group 4 medulloblastoma 3 | 1,855
lung adenocarcinoma 3 | 2,716
medulloblastoma 3 | 720
nasopharyngeal carcinoma 3 | 1,058
progressive supranuclear palsy 3 | 676
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Adult onset 2 | 82
Alcoholic Intoxication, Chronic 2 | 289
Alzheimer Disease 2 | 83
Autistic Disorder 2 | 364
Blepharoptosis 2 | 231
Bradykinesia 2 | 34
Cardiovascular system disease 2 | 246
Disease Models, Animal 2 | 155
Gastroesophageal reflux disease 2 | 110
Infantile onset 2 | 238
Isolated cases 2 | 72
Local anesthesia 2 | 40
Mesothelioma, Malignant 2 | 105
Osteochondrodysplasias 2 | 72
Parkinson Disease 2 | 64
Progressive disorder 2 | 142

Tissue

Endocrine System 27 | 18,159
Female tissues 27 | 17,400
Blood and immune system 26 | 16,909
Cardiovascular System 26 | 15,192
Digestive Tract 26 | 17,369
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Skin and soft tissues 26 | 17,230
Urinary Tract 26 | 16,678

Target Family

Non-IDG 14 | 12,091
Enzyme 5 | 4,145
Kinase 4 | 634
Transcription Factor 2 | 1,400
Ion Channel 1 | 344
Transporter 1 | 473

GO Function

protein phosphatase 2A binding 27 | 27
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Forkhead box protein O1 FOXO1 Tbio Transcription Factor -3.05358 1143.3 1478
Sodium-dependent dopamine transporter SLC6A3 Tclin Transporter -3.59848 3752.4 324
Protein SMG5 SMG5 Tbio Non-IDG -1.02024 9.67 88
CTTNBP2 N-terminal-like protein CTTNBP2NL Tbio Non-IDG 0.04 0.93 77
Serine/threonine-protein kinase greatwall MASTL Tbio Kinase -2.17166 152.5 259
Ribosomal protein S6 kinase beta-1 RPS6KB1 Tchem Kinase -3.18361 0.00000 1818
Protein SMG7 SMG7 Tbio Non-IDG -1.17329 16.2 66
cAMP-regulated phosphoprotein 19 ARPP19 Tbio Non-IDG -1.32637 21.7 25
Striatin-4 STRN4 Tbio Non-IDG -0.70720 4.01 126
Glutamate receptor ionotropic, NMDA 3A GRIN3A Tclin Ion Channel -1.89138 80.5 24