Development Level

Tbio 14 | 11,445
Tchem 2 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal sleep behavior 1 | 70
decreased body length 1 | 101
decreased circulating triglyce... 1 | 79
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
hyperactivity 1 | 148
increased coping response 1 | 4
increased exploration in new e... 1 | 8
increased monocyte cell number 1 | 63
increased vertical activity 1 | 24

Disease

Carcinoma 14 | 11,493
ovarian cancer 12 | 8,520
osteosarcoma 10 | 7,950
lung adenocarcinoma 7 | 2,716
lung cancer 7 | 4,740
medulloblastoma, large-cell 6 | 6,241
Kidney cancer 5 | 2,613
Multiple myeloma 5 | 1,332
adult high grade glioma 5 | 3,801
atypical teratoid / rhabdoid tumor 5 | 5,112
glioblastoma 5 | 5,792
lung carcinoma 5 | 2,843
non-small cell lung cancer 5 | 2,890
psoriasis 5 | 6,694
diabetes mellitus 4 | 1,728
primitive neuroectodermal tumor 4 | 3,035
ulcerative colitis 4 | 1,819
Astrocytoma, Pilocytic 3 | 3,081
Waldenstrons macroglobulinemia 3 | 765
group 3 medulloblastoma 3 | 4,104
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
malignant mesothelioma 3 | 3,232
pituitary cancer 3 | 1,972
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Amyotrophic lateral sclerosis 2 | 451
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Cryptorchidism 2 | 296
Osteoporosis 2 | 363
Pick disease 2 | 1,894
Schizophrenia 2 | 1,160
acute myeloid leukemia 2 | 783
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
dermatomyositis 2 | 966
ependymoma 2 | 4,679
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
juvenile dermatomyositis 2 | 1,187
medulloblastoma 2 | 720
mucosa-associated lymphoid tissue lymphoma 2 | 484
pancreatic cancer 2 | 2,398
primary Sjogren syndrome 2 | 735
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 1 | 21
Absence of eyebrows 1 | 31
Adenocarcinoma 1 | 122
Advanced bone age 1 | 35
Aplasia/Hypoplasia of the eyebrow 1 | 31
Atrial Septal Defects 1 | 85
Autosomal dominant nonsyndromic deafness 13 1 | 2
Autosomal dominant nonsyndromic deafness 21 1 | 3
Autosomal dominant nonsyndromic deafness 31 1 | 3
Big calvaria 1 | 147
COPD 1 | 118
Cardiac Arrhythmia 1 | 103
Cardiac arrest 1 | 36
Cardiomegaly 1 | 116
Cardiomyopathies 1 | 110
Cardiomyopathy 1 | 116
Congenital heart disease 1 | 93
Congenital sensorineural hearing loss 1 | 12
Eaton-Lambert syndrome 1 | 40
Exhibitionism 1 | 7
Gestational diabetes 1 | 26
Gonadoblastoma 1 | 34
Hereditary hemorrhagic telangiectasia 1 | 13
Hirschsprung's disease 1 | 46
Hyperactive behavior 1 | 91
Hypertrophic Cardiomyopathy 1 | 117
Increased head circumference 1 | 147
Increased size of cranium 1 | 147
Increased size of skull 1 | 147
Long QT syndrome 1 | 39
Long QT syndrome 1 1 | 20
Low posterior hairline 1 | 52
Myocardial Infarction 1 | 151
Neonatal hypoglycemia 1 | 17
Nephroblastoma 1 | 51
Ovarian Neoplasms 1 | 102
Prolonged QT interval 1 | 15
Prominent back of the head 1 | 21
Prominent occiput 1 | 21
Pulmonary Stenosis 1 | 45
Romano-Ward Syndrome 1 | 12
Sensorineural hearing loss 1 | 106
Short QT syndrome 1 | 12
Sparse or absent eyebrows 1 | 31
Sparse/absent eyebrows 1 | 31
Sudden Cardiac Death 1 | 29
Sudden infant death syndrome 1 | 32
inflammatory breast cancer 1 | 286
ovarian neoplasm 1 | 99

Tissue

Blood and immune system 18 | 16,909
Digestive Tract 18 | 17,369
Endocrine System 18 | 18,159
Female tissues 18 | 17,400
Liver and Pancreas 18 | 16,750
Male tissues 18 | 17,142
Nervous System 18 | 16,725
Respiratory system 18 | 16,393
Skin and soft tissues 18 | 17,230
Urinary Tract 18 | 16,678
Cardiovascular System 16 | 15,192

Target Family

Enzyme 8 | 4,145
Non-IDG 7 | 12,091
Ion Channel 1 | 344
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Function

protein phosphatase 1 binding 18 | 18
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein kinase Fer FER Tchem Kinase -1.86307 55.4 414
A-kinase anchor protein 11 AKAP11 Tbio Enzyme -1.02415 11.7 38
Leucine-rich repeat protein SHOC-2 SHOC2 Tbio Non-IDG -1.68905 52.6 162
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.90675 800.2 365
Neurabin-2 PPP1R9B Tdark Non-IDG 0.00000 0
Neurabin-1 PPP1R9A Tbio Non-IDG -1.00329 12.4 117
Leukocyte immunoglobulin-like receptor subfamily B member 1 LILRB1 Tbio Non-IDG -2.22487 181.7 0
Leukocyte immunoglobulin-like receptor subfamily B member 2 LILRB2 Tbio Non-IDG -2.03244 85.4 165
Phosphatase and actin regulator 3 PHACTR3 Tbio Enzyme -0.82521 7.75 95
Protein phosphatase 1 regulatory subunit 11 PPP1R11 Tbio Enzyme -1.00653 11.5 68