Development Level

Tbio 39 | 10,625
Tdark 11 | 7,003
Tchem 1 | 1,890

IMPC Term

abnormal behavior 2 | 226
preweaning lethality, complete... 2 | 633
abnormal QRS complex 1 | 25
abnormal eye size 1 | 11
decreased circulating alanine ... 1 | 53
improved glucose tolerance 1 | 56
increased exploration in new e... 1 | 56
polydactyly 1 | 22

Disease

osteosarcoma 26 | 7,933
psoriasis 26 | 6,685
glioblastoma 25 | 5,572
medulloblastoma, large-cell 24 | 6,234
ovarian cancer 24 | 8,484
lung cancer 22 | 4,466
atypical teratoid / rhabdoid tumor 20 | 4,369
ulcerative colitis 16 | 2,087
pilocytic astrocytoma 14 | 3,086
invasive ductal carcinoma 13 | 2,950
non-small cell lung cancer 13 | 2,798
adult high grade glioma 12 | 2,148
breast carcinoma 12 | 1,614
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,289
lung carcinoma 12 | 2,844
oligodendroglioma 12 | 2,849
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
lung adenocarcinoma 10 | 2,713
malignant mesothelioma 10 | 3,162
pancreatic cancer 10 | 2,300
pediatric high grade glioma 10 | 2,712
pituitary cancer 10 | 1,972
primitive neuroectodermal tumor 10 | 3,031
adrenocortical carcinoma 9 | 1,427
primary pancreatic ductal adenocarcinoma 9 | 1,271
sonic hedgehog group medulloblastoma 9 | 1,482
subependymal giant cell astrocytoma 9 | 2,287
Breast cancer 8 | 3,094
astrocytic glioma 8 | 2,241
cystic fibrosis 8 | 1,665
diabetes mellitus 8 | 1,663
interstitial cystitis 8 | 2,299
posterior fossa group A ependymoma 8 | 1,511
Cancer 7 | 2,346
colon cancer 7 | 1,475
ependymoma 7 | 2,514
gastric carcinoma 7 | 832
Atopic dermatitis 6 | 944
Waldenstrons macroglobulinemia 6 | 765
astrocytoma 6 | 1,493
ductal carcinoma in situ 6 | 1,745
group 4 medulloblastoma 6 | 1,875
juvenile dermatomyositis 6 | 1,189
medulloblastoma 6 | 1,524
Carcinoma 5 | 2,147
Duchenne muscular dystrophy 5 | 602
Rheumatoid Arthritis 5 | 1,160
active Crohn's disease 5 | 918
acute quadriplegic myopathy 5 | 1,157
aldosterone-producing adenoma 5 | 664
cutaneous lupus erythematosus 5 | 1,056
esophageal adenocarcinoma 4 | 737
mucosa-associated lymphoid tissue lymphoma 4 | 480
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
tuberculosis and treatment for 3 months 4 | 327
Atherosclerosis 3 | 275
Degenerative disc disease 3 | 28
Dermatitis, Allergic Contact 3 | 66
Multiple Sclerosis 3 | 498
Osteoarthritis 3 | 96
Pick disease 3 | 1,893
Schizophrenia 3 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
glioblastoma multiforme 3 | 347
interstitial lung disease 3 | 291
limb girdle muscular dystrophy 2A 3 | 156
nephrosclerosis 3 | 329
non primary Sjogren syndrome sicca 3 | 840
posterior fossa group B ependymoma 3 | 1,530
primary Sjogren syndrome 3 | 789
tuberculosis 3 | 1,557
urothelial carcinoma 3 | 318
Becker muscular dystrophy 2 | 187
Bipolar Disorder 2 | 266
Cerebrovascular disease 2 | 231
Chronic Lymphocytic Leukemia 2 | 242
Coronary artery disease 2 | 240
Down syndrome 2 | 548
Ehlers-Danlos syndrome 2 | 42
Endometrial Neoplasms 2 | 50
Kabuki syndrome 2 | 27
Liver diseases 2 | 66
Metabolic syndrome X 2 | 155
Multiple myeloma 2 | 1,327
Myocardial Ischemia 2 | 169
Myopia 2 | 99
Narcolepsy 2 | 58
Polycystic Ovary Syndrome 2 | 332
X-linked cerebral adrenoleukodystrophy 2 | 115
acute myeloid leukemia 2 | 780
adrenocortical adenoma 2 | 134
chronic lymphosyte leukemia 2 | 232
chronic rhinosinusitis 2 | 512
dermatomyositis 2 | 933
group 3 medulloblastoma 2 | 2,254
head and neck cancer 2 | 270
nasopharyngeal carcinoma 2 | 1,056
non diabetic and post-ischemic heart failure 2 | 200
pterygium 2 | 74

Tissue

Digestive Tract 51 | 18,473
Nervous System 51 | 18,561
Blood and immune system 50 | 17,995
Endocrine System 50 | 18,512
Female tissues 50 | 18,647
Liver and Pancreas 50 | 18,136
Skin and soft tissues 50 | 18,115
Urinary Tract 50 | 18,444
Cardiovascular System 49 | 17,958
Male tissues 49 | 17,969
Respiratory system 48 | 17,484

Target Family

Non-IDG 43 | 11,971
Enzyme 4 | 4,146
Kinase 4 | 634

GO Function

protein kinase inhibitor activ... 51 | 51
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Suppressor of cytokine signaling 1 SOCS1 Tbio Non-IDG -3.00271 1072.1 392
Suppressor of cytokine signaling 5 SOCS5 Tbio Non-IDG -2.00237 102.5 132
Reticulon-4 receptor RTN4R Tbio Non-IDG -2.54684 385.1 166
C-Jun-amino-terminal kinase-interacting protein 1 MAPK8IP1 Tbio Enzyme -2.80392 652.2 146
Tribbles homolog 1 TRIB1 Tbio Kinase -1.75554 64.1 223
Tribbles homolog 3 TRIB3 Tbio Kinase -1.83873 82.8 376
Suppressor of cytokine signaling 4 SOCS4 Tbio Non-IDG -1.16682 13.8 196
Leucine-rich repeat transmembrane protein FLRT2 FLRT2 Tbio Non-IDG -0.99170 10.9 48
Leucine-rich repeat transmembrane neuronal protein 3 LRRTM3 Tbio Non-IDG -0.71531 6.61 58
Leucine-rich repeat transmembrane neuronal protein 4 LRRTM4 Tdark Non-IDG -0.66354 4.56 54