Development Level

Tbio 19 | 11,445
Tchem 3 | 1,598
Tdark 3 | 6,588
Tclin 1 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal liver morphology 1 | 17
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart 1 | 210
improved glucose tolerance 1 | 79
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 16 | 11,493
ovarian cancer 14 | 8,520
atypical teratoid / rhabdoid tumor 12 | 5,112
osteosarcoma 12 | 7,950
Cancer 11 | 2,499
medulloblastoma, large-cell 11 | 6,241
glioblastoma 10 | 5,792
lung cancer 10 | 4,740
adult high grade glioma 8 | 3,801
Breast cancer 7 | 3,578
Kidney cancer 7 | 2,613
malignant mesothelioma 7 | 3,232
psoriasis 7 | 6,694
Astrocytoma, Pilocytic 6 | 3,081
invasive ductal carcinoma 6 | 2,951
diabetes mellitus 5 | 1,728
ductal carcinoma in situ 5 | 1,745
ependymoma 5 | 4,679
group 3 medulloblastoma 5 | 4,104
group 4 medulloblastoma 5 | 1,855
Alzheimer's disease 4 | 658
breast carcinoma 4 | 1,638
cystic fibrosis 4 | 1,696
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
Acquired metabolic disease 3 | 336
Hypertension 3 | 396
Hypertensive disease 3 | 292
Neoplasm Metastasis 3 | 168
Pancreatic Neoplasm 3 | 85
Pancreatic Neoplasms 3 | 85
Peutz-Jeghers syndrome 3 | 21
Prostatic Neoplasms 3 | 495
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
non primary Sjogren syndrome sicca 3 | 891
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
ulcerative colitis 3 | 1,819
Abdominal Pain 2 | 98
Abnormality of metabolism/homeostasis 2 | 134
Adenocarcinoma 2 | 122
Adenocarcinoma of lung 2 | 142
Adenocarcinoma of lung (disorder) 2 | 60
Adenoid Cystic Carcinoma 2 | 99
Autosomal recessive predisposition 2 | 1,442
Brain disease 2 | 96
Breast Neoplasms 2 | 445
Carcinoma, Adenoid Cystic 2 | 99
Carcinoma, Squamous Cell 2 | 110
Cardiomyopathies 2 | 110
Cowden disease 2 | 18
Down syndrome 2 | 499
Endometriosis 2 | 540
Epilepsy 2 | 792
Fatigue 2 | 182
Gastrointestinal Hemorrhage 2 | 52
Gastrointestinal hamartomatous polyps 2 | 10
Gynecomastia 2 | 64
Hamartomatous polyp 2 | 10
Heart disease 2 | 306
Hernias, Diaphragmatic, Congenital 2 | 17
Hyperpigmented macules 2 | 42
Inflammation 2 | 120
Intellectual disability 2 | 1,016
Isolated cases 2 | 72
Kidney Diseases 2 | 114
Kidney disease 2 | 430
Lung Neoplasms 2 | 232
Mammary Neoplasms 2 | 425
Melanoma 2 | 711
Myocardial Infarction 2 | 151
Myocardial Ischemia 2 | 169
Neoplasm Invasiveness 2 | 161
Neurodegenerative disease 2 | 414
Neutropenia 2 | 72
Ovarian Cysts 2 | 41
Pick disease 2 | 1,894
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Seizures 2 | 596
Somatic mutation 2 | 61
Squamous cell carcinoma 2 | 129
Syndactyly 2 | 88
Thalassemia 2 | 53
Type 2 diabetes mellitus 2 | 272
Vascular disease 2 | 319
Ventricular Septal Defects 2 | 119
Waldenstrons macroglobulinemia 2 | 765
Weight decreased 2 | 103
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
colon cancer 2 | 1,478
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 807
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
juvenile dermatomyositis 2 | 1,187
pituitary cancer 2 | 1,972

Tissue

Blood and immune system 26 | 16,909
Digestive Tract 26 | 17,369
Endocrine System 26 | 18,159
Female tissues 26 | 17,400
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Respiratory system 26 | 16,393
Skin and soft tissues 26 | 17,230
Urinary Tract 26 | 16,678
Cardiovascular System 25 | 15,192
Nervous System 25 | 16,725

Target Family

Non-IDG 14 | 12,091
Kinase 5 | 634
Enzyme 4 | 4,145
Transcription Factor 2 | 1,400
GPCR 1 | 408

GO Function

protein kinase activator activ... 26 | 26
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MAP kinase-activating death domain protein MADD Tbio Enzyme -1.86555 79.6 121
Serine/threonine-protein kinase MARK2 MARK2 Tchem Kinase -2.49873 272.3 322
Homeobox protein Nkx-3.1 NKX3-1 Tbio Transcription Factor -2.13442 140.5 524
Speedy protein A SPDYA Tbio Non-IDG -1.58097 42.8 145
Serine/threonine-protein kinase WNK1 WNK1 Tchem Kinase -2.79557 617.6 414
TOM1-like protein 1 TOM1L1 Tbio Non-IDG -0.88256 9.68 177
Metallothionein-3 MT3 Tbio Non-IDG -2.30937 197.7 87
Fibroblast growth factor 13 FGF13 Tbio Non-IDG -2.94674 831.9 368
Nck-associated protein 1-like NCKAP1L Tbio Non-IDG -1.07556 11.2 127
C-Jun-amino-terminal kinase-interacting protein 2 MAPK8IP2 Tbio Enzyme -2.78211 570.7 164