Development Level

Tbio 8 | 10,625
Tclin 4 | 602
Tchem 1 | 1,890

IMPC Term

decreased body length 2 | 108
decreased lean body mass 2 | 195
preweaning lethality, complete... 2 | 633
abnormal skin morphology 1 | 23
abnormal spleen morphology 1 | 36
decreased NK T cell number 1 | 28
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased lumbar vertebrae num... 1 | 62
decreased total body fat amoun... 1 | 186
decreased vertical activity 1 | 22
embryonic lethality prior to t... 1 | 187
increased exploration in new e... 1 | 56
increased heart rate 1 | 17
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
shortened RR interval 1 | 19
shortened ST segment 1 | 9

Disease

ovarian cancer 10 | 8,484
medulloblastoma, large-cell 8 | 6,234
osteosarcoma 8 | 7,933
atypical teratoid / rhabdoid tumor 7 | 4,369
glioblastoma 7 | 5,572
Breast cancer 6 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
oligodendroglioma 6 | 2,849
psoriasis 6 | 6,685
tuberculosis 6 | 1,557
ependymoma 5 | 2,514
group 4 medulloblastoma 5 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
lung cancer 5 | 4,466
pancreatic cancer 5 | 2,300
pediatric high grade glioma 5 | 2,712
Cancer 4 | 2,346
Carney complex 4 | 23
Pick disease 4 | 1,893
acute quadriplegic myopathy 4 | 1,157
astrocytoma 4 | 1,493
diabetes mellitus 4 | 1,663
lung adenocarcinoma 4 | 2,713
malignant mesothelioma 4 | 3,162
pilocytic astrocytoma 4 | 3,086
subependymal giant cell astrocytoma 4 | 2,287
Alzheimer's disease 3 | 644
Amyotrophic Lateral Sclerosis 3 | 431
Heart disease 3 | 279
Osteoarthritis 3 | 96
Parkinson's disease 3 | 364
Primary pigmented nodular adrenocortical disease 3 | 12
Rheumatoid Arthritis 3 | 1,160
active Crohn's disease 3 | 918
colon cancer 3 | 1,475
cystic fibrosis 3 | 1,665
ductal carcinoma in situ 3 | 1,745
hereditary spastic paraplegia 3 | 313
pancreatic carcinoma 3 | 567
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
primitive neuroectodermal tumor 3 | 3,031
Animal Mammary Neoplasms 2 | 136
Bipolar Disorder 2 | 266
Bipolar affective disorder, current episode manic 2 | 13
Bipolar disorder in remission 2 | 19
Child Development Disorders, Pervasive 2 | 55
Depressive disorder 2 | 48
Down syndrome 2 | 548
Duchenne muscular dystrophy 2 | 602
Dysmenorrhea 2 | 19
Familial atrial fibrillation 2 | 16
Fever 2 | 34
Headache disorder 2 | 20
Juvenile rheumatoid arthritis 2 | 104
Long QT syndrome 2 | 52
Mammary Neoplasms, Experimental 2 | 150
Myocardial Infarction 2 | 126
Pain 2 | 70
Prostatic Neoplasms 2 | 471
Schizophrenia 2 | 501
astrocytic glioma 2 | 2,241
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
esophageal adenocarcinoma 2 | 737
gastric cancer 2 | 430
group 3 medulloblastoma 2 | 2,254
interstitial cystitis 2 | 2,299
invasive ductal carcinoma 2 | 2,950
juvenile dermatomyositis 2 | 1,189
medulloblastoma 2 | 1,524
pituitary cancer 2 | 1,972
posterior fossa group B ependymoma 2 | 1,530
primary pancreatic ductal adenocarcinoma 2 | 1,271
sarcoidosis 2 | 358
ulcerative colitis 2 | 2,087
46 XY gonadal dysgenesis 1 | 9
Adrenal adenoma 1 | 5
Arrhythmogenic right ventricular cardiomyopathy 1 | 27
Arthritis, Experimental 1 | 39
Brachydactyly 1 | 52
CEROID LIPOFUSCINOSIS, NEURONAL, 6 1 | 7
Campomelic dysplasia 1 | 7
Chronic heart failure 1 | 46
Common variable immunodeficiency 1 | 72
Congenital adrenal hyperplasia 1 | 74
Congenital nystagmus 1 | 26
Craniofacial Abnormalities 1 | 147
Eaton-Lambert syndrome 1 | 40
Gonadoblastoma 1 | 27
Heart failure 1 | 80
Hypogonadism 1 | 70
Hypospadias 1 | 65
Kidney cancer 1 | 118
Muscular atrophy 1 | 67
Romano-Ward Syndrome 1 | 12
Sensorineural hearing loss 1 | 107
Short QT syndrome 1 | 12
Sideroblastic anemia 1 | 18
Sudden infant death syndrome 1 | 33
Swyer Syndrome 1 | 8

Tissue

Blood and immune system 13 | 17,995
Cardiovascular System 13 | 17,958
Digestive Tract 13 | 18,473
Endocrine System 13 | 18,512
Female tissues 13 | 18,647
Liver and Pancreas 13 | 18,136
Male tissues 13 | 17,969
Nervous System 13 | 18,561
Respiratory system 13 | 17,484
Skin and soft tissues 13 | 18,115
Urinary Tract 13 | 18,444

Target Family

Enzyme 6 | 4,146
Kinase 3 | 634
Ion Channel 2 | 341
Non-IDG 1 | 11,971
Transcription Factor 1 | 1,400

GO Function

protein kinase A catalytic sub... 13 | 13
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.92762 876.7 339
Glycogen synthase kinase-3 beta GSK3B Tclin Kinase -2.94349 567.7 767
Glycogen synthase kinase-3 alpha GSK3A Tclin Kinase -1.81647 52.3 722
cAMP-dependent protein kinase type II-alpha regulatory subunit PRKAR2A Tbio Enzyme -0.84292 6.74 237
E3 ubiquitin-protein ligase Praja-2 PJA2 Tbio Enzyme -0.52612 2.59 159
Tyrosine-protein kinase CSK CSK Tchem Kinase -2.52806 262.2 489
Ezrin EZR Tbio Non-IDG -2.95879 942.2 903
Transcription factor SOX-9 SOX9 Tbio Transcription Factor -3.07045 1202.5 546
cAMP-dependent protein kinase inhibitor alpha PKIA Tbio Enzyme -1.27069 18.5 26
cAMP-dependent protein kinase type I-alpha regulatory subunit PRKAR1A Tbio Enzyme -2.34963 245.0 230