Development Level

Tbio 21 | 11,445
Tdark 3 | 6,588
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
decreased vertical activity 2 | 208
preweaning lethality, complete... 2 | 979
abnormal coat- hair morphology 1 | 19
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal liver size 1 | 5
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal stomach morphology 1 | 10
decreased circulating serum al... 1 | 82
decreased leukocyte cell numbe... 1 | 73
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
female infertility 1 | 60
improved glucose tolerance 1 | 79
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased red blood cell distr... 1 | 34
thrombocytosis 1 | 27

Disease

atypical teratoid / rhabdoid tumor 17 | 5,112
Carcinoma 16 | 11,493
glioblastoma 15 | 5,792
ovarian cancer 15 | 8,520
medulloblastoma, large-cell 14 | 6,241
osteosarcoma 14 | 7,950
ependymoma 13 | 4,679
lung cancer 13 | 4,740
adult high grade glioma 11 | 3,801
oligodendroglioma 11 | 2,850
Astrocytoma, Pilocytic 10 | 3,081
primitive neuroectodermal tumor 10 | 3,035
astrocytic glioma 9 | 2,597
group 3 medulloblastoma 9 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
invasive ductal carcinoma 8 | 2,951
psoriasis 8 | 6,694
lung carcinoma 7 | 2,843
pancreatic cancer 7 | 2,398
Kidney cancer 6 | 2,613
medulloblastoma 6 | 720
pituitary cancer 6 | 1,972
tuberculosis 6 | 2,010
Breast cancer 5 | 3,578
Cancer 5 | 2,499
Pick disease 5 | 1,894
lung adenocarcinoma 5 | 2,716
non-small cell lung cancer 5 | 2,890
Bipolar Disorder 4 | 666
Melanoma 4 | 711
astrocytoma 4 | 1,146
colon cancer 4 | 1,478
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 1,819
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
Skin cancer 3 | 469
active Crohn's disease 3 | 922
malignant mesothelioma 3 | 3,232
primary pancreatic ductal adenocarcinoma 3 | 1,109
Alcohol dependence 2 | 107
Alzheimer's disease 2 | 658
Amyotrophic lateral sclerosis 2 | 451
Attention deficit hyperactivity disorder 2 | 278
Breast Neoplasms 2 | 445
Carcinoma, Renal Cell 2 | 124
Common variable immunodeficiency 2 | 101
Conduct disorder 2 | 33
Congenital nystagmus 2 | 26
Crohn's disease 2 | 321
Down syndrome 2 | 499
Duchenne muscular dystrophy 2 | 601
Dysthymic Disorder 2 | 17
Gaucher disease type 1 2 | 180
Large intestine cancer 2 | 126
Major Depressive Disorder 2 | 301
Male infertility 2 | 206
Mammary Neoplasms 2 | 425
Multiple myeloma 2 | 1,332
Neurofibromatosis 2 | 40
Nicotine dependence 2 | 54
Obesity 2 | 678
Oppositional defiant disorder 2 | 17
Parkinson's disease 2 | 392
Pathological gambling 2 | 15
Personality disorder 2 | 25
Polycystic ovary syndrome 2 | 360
Prostatic Neoplasms 2 | 495
Renal Cell Carcinoma 2 | 214
Substance abuse 2 | 59
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
fibroadenoma 2 | 559
gastric cancer 2 | 459
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
hereditary spastic paraplegia 2 | 318
interstitial cystitis 2 | 2,312
progressive supranuclear palsy 2 | 676
urothelial carcinoma 2 | 318
Animal Mammary Neoplasms 1 | 136
Azoospermia 1 | 110
Cardiomegaly 1 | 116
Esophageal Neoplasms 1 | 69
Lymphoid leukemia 1 | 160
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Profound sensorineural hearing impairment 1 | 4
REM sleep behavior disorder 1 | 14
Relapsing fever 1 | 14
interstitial lung disease 1 | 298
sarcoidosis 1 | 370

Tissue

Endocrine System 25 | 18,159
Blood and immune system 24 | 16,909
Digestive Tract 24 | 17,369
Female tissues 24 | 17,400
Liver and Pancreas 24 | 16,750
Nervous System 24 | 16,725
Skin and soft tissues 24 | 17,230
Urinary Tract 24 | 16,678
Cardiovascular System 23 | 15,192
Male tissues 23 | 17,142
Respiratory system 23 | 16,393

Target Family

Enzyme 14 | 4,145
Non-IDG 10 | 12,091
Kinase 1 | 634
Nuclear Receptor 1 | 48

GO Function

protein kinase A binding 26 | 26
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
A-kinase anchor protein 11 AKAP11 Tbio Enzyme -1.02415 11.7 38
Dapper homolog 1 DACT1 Tbio Non-IDG -1.86707 79.6 106
Wiskott-Aldrich syndrome protein family member 2 WASF2 Tbio Non-IDG -2.90666 762.6 254
A-kinase anchor protein 12 AKAP12 Tbio Enzyme -2.00948 126.8 160
40S ribosomal protein S3 RPS3 Tbio Non-IDG -2.19489 157.7 218
Radixin RDX Tbio Non-IDG -2.47844 221.4 333
A-kinase anchor protein 10, mitochondrial AKAP10 Tbio Enzyme -1.41570 26.7 202
Dapper homolog 2 DACT2 Tbio Non-IDG -1.13921 19.1 55
A-kinase anchor protein SPHKAP SPHKAP Tdark Enzyme -0.47192 2.74 41
A-kinase anchor protein 4 AKAP4 Tbio Enzyme -1.95952 93.1 116