Development Level

Tbio 14 | 11,178
Tchem 6 | 1,885
Tclin 1 | 612
Tdark 1 | 6,569

IMPC Phenotype

embryonic lethality prior to t... 1 | 278
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 13 | 8,297
Carcinoma 11 | 11,192
osteosarcoma 11 | 7,766
glioblastoma 8 | 5,635
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,204
lung cancer 7 | 4,607
psoriasis 7 | 6,514
atypical teratoid / rhabdoid tumor 6 | 4,971
ependymoma 6 | 4,559
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,902
malignant mesothelioma 6 | 3,135
tuberculosis 6 | 1,963
Breast cancer 5 | 3,469
astrocytic glioma 5 | 2,530
invasive ductal carcinoma 5 | 2,867
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,872
medulloblastoma, large-cell 4 | 6,086
non-small cell lung cancer 4 | 2,799
pancreatic cancer 4 | 2,322
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,911
Cancer 3 | 2,388
Multiple myeloma 3 | 1,296
Vascular disease 3 | 294
active Crohn's disease 3 | 882
ductal carcinoma in situ 3 | 1,686
group 3 medulloblastoma 3 | 4,002
oligodendroglioma 3 | 2,768
pituitary cancer 3 | 1,915
primary pancreatic ductal adenocarcinoma 3 | 1,071
subependymal giant cell astrocytoma 3 | 2,230
Amyotrophic lateral sclerosis 2 | 437
Autosomal recessive predisposition 2 | 1,407
Contact Dermatitis 2 | 77
Degenerative polyarthritis 2 | 110
Dermatitis, Contact 2 | 67
Duchenne muscular dystrophy 2 | 587
Kidney cancer 2 | 2,548
Mesothelioma, Malignant 2 | 103
Neoplasms 2 | 57
Neurodegenerative disease 2 | 402
Osteoarthritis 2 | 179
Pick disease 2 | 1,856
Prostatic Neoplasms 2 | 472
acute quadriplegic myopathy 2 | 1,133
adrenocortical carcinoma 2 | 1,385
adult high grade glioma 2 | 3,701
diabetes mellitus 2 | 1,683
lung adenocarcinoma 2 | 2,627
lung carcinoma 2 | 2,755
medulloblastoma 2 | 702
mucosa-associated lymphoid tissue lymphoma 2 | 473
pediatric high grade glioma 2 | 1,035
primitive neuroectodermal tumor 2 | 2,957
spina bifida 2 | 1,053
Acquired immunodeficiency syndrome 1 | 192
Acute Lung Injury 1 | 21
Acute kidney injury 1 | 67
Alopecia 1 | 113
Anemia, Sideroblastic 1 | 7
Angioedema 1 | 33
Bacillary angiomatosis 1 | 6
Barrett's esophagus 1 | 173
Bipolar disorder in remission 1 | 19
Cardiomegaly 1 | 114
Colorectal Neoplasms 1 | 235
Combined oxidative phosphorylation deficiency 1 | 14
Common cold 1 | 66
Cough 1 | 23
Echinococcosis 1 | 26
Entropion 1 | 22
Friedreich ataxia 1 | 24
General anesthesia 1 | 53
Hypertensive Retinopathy 1 | 14
Itching of skin 1 | 18
Learning disability 1 | 16
Leptospirosis 1 | 18
Leukopenia 1 | 72
Liver disease 1 | 227
Liver diseases 1 | 85
Lyme disease 1 | 26
Manic 1 | 13
Manic mood 1 | 6
Menkes disease 1 | 19
Mitochondrial complex I deficiency 1 | 46
Nasal congestion 1 | 23
Nausea and vomiting 1 | 93
Nonsyndromic deafness 1 | 137
Pityriasis versicolor 1 | 19
Primary ciliary dyskinesia 1 | 75
Scurvy 1 | 10
Seborrheic dermatitis 1 | 31
Sensorineural Hearing Loss (disorder) 1 | 281
Sideroblastic anemia 1 | 20
Spinal Dysraphism 1 | 12
Thyroid Neoplasm 1 | 37
Thyroid Neoplasms 1 | 34
Trichinosis 1 | 7
Tularemia 1 | 23
Wilson-Turner syndrome 1 | 14
inflammatory breast cancer 1 | 272

Tissue

Endocrine System 22 | 18,159
Male tissues 22 | 17,142
Blood and immune system 21 | 16,909
Digestive Tract 21 | 17,369
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678
Cardiovascular System 20 | 15,192

Target Family

Non-IDG 16 | 12,091
Enzyme 6 | 4,145

GO Function

protein disulfide oxidoreducta... 22 | 22
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ERO1-like protein alpha ERO1A Tbio Non-IDG -1.54976 34.5 230
Thioredoxin reductase 1, cytoplasmic TXNRD1 Tclin Enzyme -2.28524 208.2 308
Glutaredoxin domain-containing cysteine-rich protein 1 GRXCR1 Tdark Non-IDG -0.45230 3.09 43
Glutaredoxin-related protein 5, mitochondrial GLRX5 Tbio Non-IDG -1.86742 74.9 111
Glutaredoxin-2, mitochondrial GLRX2 Tbio Non-IDG -1.92624 85.5 114
Thioredoxin reductase 3 TXNRD3 Tchem Enzyme -1.72626 60.0 0
Thioredoxin domain-containing protein 2 TXNDC2 Tbio Non-IDG -0.71996 6.88 19
Stabilin-1 STAB1 Tbio Non-IDG -1.61013 45.4 107
Thioredoxin-like protein 1 TXNL1 Tbio Non-IDG -2.32888 224.7 143
Ecto-NOX disulfide-thiol exchanger 2 ENOX2 Tchem Non-IDG -1.14149 16.1 125