Development Level

Tbio 15 | 11,445
Tchem 4 | 1,598
Tdark 2 | 6,588
Tclin 1 | 613

IMPC Phenotype

embryonic lethality prior to t... 1 | 278
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 13 | 8,520
Carcinoma 11 | 11,493
osteosarcoma 11 | 7,950
glioblastoma 8 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung cancer 7 | 4,740
psoriasis 7 | 6,694
atypical teratoid / rhabdoid tumor 6 | 5,112
ependymoma 6 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
malignant mesothelioma 6 | 3,232
tuberculosis 6 | 2,010
Breast cancer 5 | 3,578
astrocytic glioma 5 | 2,597
invasive ductal carcinoma 5 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
medulloblastoma, large-cell 4 | 6,241
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Cancer 3 | 2,499
Multiple myeloma 3 | 1,332
Vascular disease 3 | 319
active Crohn's disease 3 | 922
ductal carcinoma in situ 3 | 1,745
group 3 medulloblastoma 3 | 4,104
oligodendroglioma 3 | 2,850
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287
Amyotrophic lateral sclerosis 2 | 451
Autosomal recessive predisposition 2 | 1,442
Contact Dermatitis 2 | 81
Degenerative polyarthritis 2 | 115
Dermatitis, Contact 2 | 71
Duchenne muscular dystrophy 2 | 601
Kidney cancer 2 | 2,613
Mesothelioma, Malignant 2 | 105
Neoplasms 2 | 63
Neurodegenerative disease 2 | 414
Osteoarthritis 2 | 184
Pick disease 2 | 1,894
Prostatic Neoplasms 2 | 495
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
diabetes mellitus 2 | 1,728
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
medulloblastoma 2 | 720
mucosa-associated lymphoid tissue lymphoma 2 | 484
pediatric high grade glioma 2 | 1,064
primitive neuroectodermal tumor 2 | 3,035
spina bifida 2 | 1,074
Acquired immunodeficiency syndrome 1 | 197
Acute Lung Injury 1 | 22
Acute kidney injury 1 | 70
Alopecia 1 | 115
Anemia, Sideroblastic 1 | 7
Angioedema 1 | 38
Bacillary angiomatosis 1 | 6
Barrett's esophagus 1 | 182
Bipolar disorder in remission 1 | 19
Cardiomegaly 1 | 116
Colorectal Neoplasms 1 | 243
Combined oxidative phosphorylation deficiency 1 | 14
Common cold 1 | 67
Cough 1 | 23
Echinococcosis 1 | 26
Entropion 1 | 22
Friedreich ataxia 1 | 24
General anesthesia 1 | 53
Hypertensive Retinopathy 1 | 14
Itching of skin 1 | 18
Learning disability 1 | 17
Leptospirosis 1 | 18
Leukopenia 1 | 72
Liver disease 1 | 237
Liver diseases 1 | 87
Lyme disease 1 | 26
Manic 1 | 14
Manic mood 1 | 6
Menkes disease 1 | 19
Mitochondrial complex I deficiency 1 | 46
Nasal congestion 1 | 21
Nausea and vomiting 1 | 97
Nonsyndromic deafness 1 | 142
Pityriasis versicolor 1 | 19
Primary ciliary dyskinesia 1 | 76
Scurvy 1 | 10
Seborrheic dermatitis 1 | 31
Sensorineural Hearing Loss (disorder) 1 | 284
Sideroblastic anemia 1 | 20
Spinal Dysraphism 1 | 12
Thyroid Neoplasm 1 | 37
Thyroid Neoplasms 1 | 34
Trichinosis 1 | 7
Tularemia 1 | 23
Wilson-Turner syndrome 1 | 14
inflammatory breast cancer 1 | 286

Tissue

Endocrine System 22 | 18,159
Male tissues 22 | 17,142
Blood and immune system 21 | 16,909
Digestive Tract 21 | 17,369
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678
Cardiovascular System 20 | 15,192

Target Family

Non-IDG 16 | 12,091
Enzyme 6 | 4,145

GO Function

protein disulfide oxidoreducta... 22 | 22
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Stabilin-1 STAB1 Tbio Non-IDG -1.61013 45.4 107
Glutaredoxin domain-containing cysteine-rich protein 1 GRXCR1 Tdark Non-IDG -0.45230 3.09 43
Thioredoxin domain-containing protein 2 TXNDC2 Tbio Non-IDG -0.71996 6.88 19
Thioredoxin reductase 3 TXNRD3 Tdark Enzyme -1.72626 60.0 0
Thioredoxin-like protein 1 TXNL1 Tbio Non-IDG -2.32888 224.7 143
Ecto-NOX disulfide-thiol exchanger 2 ENOX2 Tbio Non-IDG -1.14149 16.1 125
Thioredoxin reductase 1, cytoplasmic TXNRD1 Tclin Enzyme -2.28524 208.2 308
ERO1-like protein alpha ERO1A Tbio Non-IDG -1.54976 34.5 230
Copper chaperone for superoxide dismutase CCS Tbio Enzyme -1.76183 50.7 209
Glutaredoxin-related protein 5, mitochondrial GLRX5 Tbio Non-IDG -1.86742 74.9 111