Development Level

Tbio 71 | 11,445
Tchem 19 | 1,598
Tclin 14 | 613
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal embryo size 3 | 220
embryonic lethality prior to t... 3 | 278
increased heart weight 3 | 62
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
abnormal femur morphology 2 | 14
decreased T cell number 2 | 15
decreased circulating glucose ... 2 | 126
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
increased mean corpuscular vol... 2 | 92
increased spleen weight 2 | 10
pallor 2 | 34
small superior vagus ganglion 2 | 74
vertebral fusion 2 | 23
abnormal allantois morphology 1 | 8
abnormal bone mineralization 1 | 38
abnormal chorioallantoic fusio... 1 | 8
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal heart morphology 1 | 162
abnormal humerus morphology 1 | 11
abnormal limb bud morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal retinal blood vessel ... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal vibrissa morphology 1 | 25
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
decreased IgG1 level 1 | 8
decreased bone mineral content 1 | 151
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating triglyce... 1 | 79
decreased circulating unsatura... 1 | 2
decreased exploration in new e... 1 | 11
decreased fluid intake 1 | 3
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
hemorrhage 1 | 23
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased CD4-positive, alpha ... 1 | 4
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 36
increased respiratory quotient 1 | 2
pale yolk sac 1 | 25

Disease

Carcinoma 66 | 11,493
ovarian cancer 60 | 8,520
psoriasis 53 | 6,694
osteosarcoma 52 | 7,950
Cancer 48 | 2,499
lung cancer 48 | 4,740
glioblastoma 45 | 5,792
malignant mesothelioma 37 | 3,232
pancreatic cancer 37 | 2,398
Breast cancer 33 | 3,578
diabetes mellitus 33 | 1,728
Astrocytoma, Pilocytic 31 | 3,081
non-small cell lung cancer 31 | 2,890
lung carcinoma 30 | 2,843
ependymoma 29 | 4,679
invasive ductal carcinoma 29 | 2,951
ulcerative colitis 28 | 1,819
adult high grade glioma 27 | 3,801
atypical teratoid / rhabdoid tumor 27 | 5,112
lung adenocarcinoma 27 | 2,716
medulloblastoma, large-cell 27 | 6,241
Autosomal recessive predisposition 26 | 1,442
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
Kidney disease 24 | 430
group 3 medulloblastoma 24 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
interstitial cystitis 22 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,962
Schizophrenia 21 | 1,160
ductal carcinoma in situ 21 | 1,745
Kidney cancer 20 | 2,613
primary pancreatic ductal adenocarcinoma 20 | 1,109
tuberculosis 20 | 2,010
subependymal giant cell astrocytoma 19 | 2,287
Hypertension 18 | 396
gastric carcinoma 18 | 807
Liver disease 17 | 237
colon cancer 17 | 1,478
cutaneous lupus erythematosus 17 | 1,057
cystic fibrosis 17 | 1,696
oligodendroglioma 17 | 2,850
primitive neuroectodermal tumor 17 | 3,035
Liver Cirrhosis, Experimental 16 | 769
breast carcinoma 16 | 1,638
esophageal adenocarcinoma 16 | 737
Alzheimer's disease 15 | 658
Anemia 15 | 365
Atopic dermatitis 15 | 952
Rheumatoid arthritis 15 | 1,191
Vascular disease 15 | 319
nasopharyngeal carcinoma 15 | 1,058
Bipolar Disorder 14 | 666
Cerebrovascular disease 14 | 238
Heart disease 14 | 306
Hypertensive disease 14 | 292
pituitary cancer 14 | 1,972
Hypersensitivity reaction type II disease 13 | 253
Atherosclerosis 12 | 291
Coronary artery disease 12 | 268
Lung disease 12 | 142
Obesity 12 | 678
Prostatic Neoplasms 12 | 495
astrocytic glioma 12 | 2,597
juvenile dermatomyositis 12 | 1,187
Arthritis 11 | 290
Duchenne muscular dystrophy 11 | 601
adrenocortical carcinoma 11 | 1,428
Melanoma 10 | 711
Myocardial Infarction 10 | 151
astrocytoma 10 | 1,146
non primary Sjogren syndrome sicca 10 | 891
spina bifida 10 | 1,074
Asthma 9 | 385
Becker muscular dystrophy 9 | 191
Brain disease 9 | 96
Breast Neoplasms 9 | 445
Dementia 9 | 175
Disseminated intravascular coagulation 9 | 38
Fever 9 | 138
Inflammatory bowel disease 9 | 151
Mammary Neoplasms 9 | 425
Pancreatitis 9 | 123
Stomach Neoplasms 9 | 300
Thrombocytopenia 9 | 197
acute quadriplegic myopathy 9 | 1,158
fibroadenoma 9 | 559
mucosa-associated lymphoid tissue lymphoma 9 | 484
Abortion, Spontaneous 8 | 109
Depressive disorder 8 | 409
Endometriosis 8 | 540
Liver Cirrhosis 8 | 181
Lung Neoplasms 8 | 232
Mesothelioma, Malignant 8 | 105
Multiple Sclerosis 8 | 540
Neurodegenerative disease 8 | 414
Spontaneous abortion 8 | 113
active ulcerative colitis 8 | 764
dermatomyositis 8 | 966
limb girdle muscular dystrophy 2A 8 | 213

Tissue

Endocrine System 106 | 18,159
Female tissues 105 | 17,400
Digestive Tract 102 | 17,369
Male tissues 102 | 17,142
Urinary Tract 102 | 16,678
Skin and soft tissues 100 | 17,230
Liver and Pancreas 99 | 16,750
Blood and immune system 98 | 16,909
Respiratory system 97 | 16,393
Cardiovascular System 92 | 15,192
Nervous System 92 | 16,725

Target Family

Non-IDG 77 | 12,091
Enzyme 20 | 4,145
Kinase 4 | 634
Transcription Factor 3 | 1,400
Ion Channel 2 | 344
GPCR 1 | 408
Transporter 1 | 473

GO Function

protease binding 108 | 108
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
Pannexin-1 PANX1 Tbio Ion Channel -2.59888 418.5 154
Lon protease homolog 2, peroxisomal LONP2 Tbio Enzyme -1.00177 8.20 100
Derlin-1 DERL1 Tbio Non-IDG -1.88253 69.7 178
E3 ubiquitin-protein ligase RNF139 RNF139 Tbio Enzyme -1.17169 16.6 133
Death domain-containing protein CRADD CRADD Tbio Non-IDG -1.34614 23.0 400
Prolyl endopeptidase FAP FAP Tchem Enzyme -2.37686 226.2 406
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.74914 5601.8 1083
Fibronectin FN1 Tchem Non-IDG -3.09873 1208.8 1583
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143