Development Level

Tbio 4 | 11,445

IMPC Phenotype

abnormal retina morphology 1 | 71
absent spleen 1 | 3
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 4 | 11,493
atypical teratoid / rhabdoid tumor 3 | 5,112
medulloblastoma, large-cell 3 | 6,241
ovarian cancer 3 | 8,520
psoriasis 3 | 6,694
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Microsatellite Instability 2 | 12
Multiple myeloma 2 | 1,332
Pick disease 2 | 1,894
Wilms Tumor 2 | 28
astrocytic glioma 2 | 2,597
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
hepatocellular carcinoma 2 | 547
malignant mesothelioma 2 | 3,232
oligodendroglioma 2 | 2,850
primitive neuroectodermal tumor 2 | 3,035
Abnormality of metabolism/homeostasis 1 | 134
Alveolar echinococcosis 1 | 7
Alzheimer's disease 1 | 658
Amyotrophic lateral sclerosis 1 | 451
Basal cell carcinoma 1 | 54
Basal cell nevi 1 | 23
Bradykinesia 1 | 34
Craniofacial Abnormalities 1 | 151
Crohn's disease 1 | 321
Cystic nephroma 1 | 5
Deglutition Disorders 1 | 132
Delayed speech and language development 1 | 112
Dysarthria 1 | 192
Dystonia 1 | 164
Dystonia Disorders 1 | 6
Dystonia, Limb 1 | 9
Dystonic Disorders 1 | 7
Endometrial cancer 1 | 311
Endometriosis 1 | 540
Euthyroid Goiter 1 | 3
Euthyroid multinodular goiter 1 | 1
Familial multinodular goiter 1 | 1
Fragile X syndrome 1 | 34
GOITER, MULTINODULAR 1, WITH OR WITHOUT SERTOLI-LEYDIG CELL TUMORS 1 | 1
Gaucher disease type 1 1 | 180
Goiter 1 | 38
Granulosa Cell Cancer 1 | 1
Granulosa cell tumor 1 | 6
Gynandroblastoma 1 | 1
Hyperreflexia 1 | 209
Hypomyelinating leukodystrophy 6 1 | 26
Kidney cancer 1 | 2,613
Language Delay 1 | 112
Laryngeal dystonia 1 | 5
Liver cancer 1 | 604
Malignant Granulosa Cell Tumor 1 | 1
Morphological abnormality of the pyramidal tract 1 | 12
Motor delay 1 | 147
Multinodular goiter 1 | 3
No development of motor milestones 1 | 147
Oligospermia 1 | 36
Papillary thyroid carcinoma 1 | 43
Parkinson's disease 1 | 392
Parkinsonian Disorders 1 | 56
Pleuropulmonary blastoma 1 | 1
Polyp of large intestine 1 | 8
Progressive disorder 1 | 142
Pyramidal sign 1 | 29
Pyramidal tract disease 1 | 12
Renal Cell Carcinoma 1 | 214
Retinitis pigmentosa 18 1 | 16
Rhabdomyosarcoma 1 | 39
Rhabdomyosarcoma, Embryonal 1 | 5
Rheumatoid arthritis 1 | 1,191
Schizophrenia 1 | 1,160
Seminoma 1 | 15
Sertoli cell neoplasm 1 | 1
Sertoli-Leydig cell tumor 1 | 5
Shipyard eye 1 | 15
Speech Delay 1 | 112
Speech impairment 1 | 112
Static Tremor 1 | 21
Waldenstrons macroglobulinemia 1 | 765
Waterhouse-Friderichsen syndrome 1 | 11
acute myeloid leukemia 1 | 783
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
dermatomyositis 1 | 966
hereditary spastic paraplegia 1 | 318
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
juvenile dermatomyositis 1 | 1,187
medulloblastoma 1 | 720
non-small cell lung cancer 1 | 2,890
osteosarcoma 1 | 7,950
ovarian neoplasm 1 | 99
pancreatic cancer 1 | 2,398
pancreatic carcinoma 1 | 562
permanent atrial fibrillation 1 | 45
progressive supranuclear palsy 1 | 676
sarcoidosis 1 | 370
tuberculosis and treatment for 6 months 1 | 409
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Non-IDG 2 | 12,091
Enzyme 1 | 4,145
Kinase 1 | 634

GO Function

pre-miRNA binding 4 | 4
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interferon-inducible double-stranded RNA-dependent protein kinase activator A PRKRA Tbio Kinase -1.51727 34.3 299
Exportin-5 XPO5 Tbio Non-IDG -1.97361 83.7 166
Endoribonuclease Dicer DICER1 Tbio Enzyme -3.34177 2054.3 327
RISC-loading complex subunit TARBP2 TARBP2 Tbio Non-IDG -3.11849 1238.4 273