Development Level

Tbio 2 | 11,445
Tclin 1 | 613

IMPC Phenotype

abnormal behavior 1 | 298
decreased grip strength 1 | 116
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating total pr... 1 | 28

Disease

Carcinoma 3 | 11,493
Astrocytoma, Pilocytic 2 | 3,081
Epilepsy 2 | 792
Kidney cancer 2 | 2,613
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
invasive ductal carcinoma 2 | 2,951
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
Animal Mammary Neoplasms 1 | 136
Autosomal recessive polycystic kidney disease 1 | 41
Axonal neuropathy 1 | 27
Babinski Reflex 1 | 100
Benign epilepsy with centrotemporal spikes 1 | 13
Blepharoptosis 1 | 231
Brachycephaly 1 | 88
Brain Edema 1 | 50
Broad cranium shape 1 | 88
Cerebrospinal fluid protein increased above normal 1 | 14
Choledochal Cyst 1 | 9
Contracture of joint 1 | 93
Decreased motor NCV 1 | 22
Decreased projection of maxilla 1 | 66
Decreased sensory nerve conduction velocities (NCV) 1 | 8
Deficiency of upper jaw bones 1 | 66
Dilated ventricles (finding) 1 | 121
Dizziness 1 | 26
Dysarthria 1 | 192
EMG: chronic denervation signs 1 | 4
Eaton-Lambert syndrome 1 | 40
Edema, Cardiac 1 | 3
Electromyogram abnormal 1 | 49
Episodic ataxia 1 | 22
Episodic ataxia type 1 1 | 4
Facial asymmetry 1 | 32
Fibrogenesis imperfecta ossium 1 | 2
Flexion contracture 1 | 93
Flexion contractures of joints 1 | 93
Generalized hypotonia 1 | 37
Hand deformities 1 | 32
Headache 1 | 37
Hemiplegia and hemiparesis 1 | 38
Hereditary motor and sensory neuropathy with agenesis of the corpus callosum 1 | 3
Highly variable severity 1 | 157
Hydrarthrosis 1 | 4
Hyperthyroidism 1 | 53
Hypoplasia of the maxilla 1 | 66
Hypotrophic maxilla 1 | 66
Juvenile myoclonic epilepsy 1 | 21
Large auricle 1 | 87
Large dysplastic ears 1 | 87
Large pinnae 1 | 87
Large prominent ears 1 | 87
Large protruding ears 1 | 87
Large, floppy ears 1 | 87
Low anterior hairline 1 | 30
Macrotia 1 | 87
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Maxillary retrognathia 1 | 66
Meniere's disease 1 | 24
Motor delay 1 | 147
Muscle weakness of limb 1 | 21
Narrow forehead 1 | 34
Neonatal Hypotonia 1 | 64
Neurogenic Muscular Atrophy 1 | 139
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
No development of motor milestones 1 | 147
Onion bulb formation 1 | 19
Pain 1 | 103
Peripheral Nervous System Diseases 1 | 52
Peripheral Neuropathy 1 | 134
Peripheral axonal neuropathy 1 | 18
Peripheral motor neuropathy 1 | 4
Polycystic Kidney, Autosomal Recessive 1 | 9
Polyhydramnios 1 | 108
Polyneuropathy 1 | 64
Polyneuropathy, Motor 1 | 4
Pulmonary edema 1 | 17
Respiratory Tract Infections 1 | 7
Retrusion of upper jaw bones 1 | 66
Salivary Gland Neoplasms 1 | 46
Sensory neuropathy 1 | 20
Septic Shock 1 | 5
Shock, Septic 1 | 6
Simple syndactyly of toes, first web space 1 | 23
Skeletal muscle atrophy 1 | 139
Spastic gait 1 | 23
Spinal Cord Injuries 1 | 8
Tapering fingers (finding) 1 | 25
Tremor 1 | 113
Tremor, Limb 1 | 2
Urinary tract obstruction 1 | 11
Variable expressivity 1 | 157
Vertigo 1 | 29
Wide skull shape 1 | 88
inflammatory breast cancer 1 | 286
muscle degeneration 1 | 139

Tissue

Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Nervous System 3 | 16,725
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678
Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Male tissues 2 | 17,142
Respiratory system 2 | 16,393

Target Family

Ion Channel 1 | 344
Non-IDG 1 | 12,091
Transporter 1 | 473

GO Function

potassium ion transmembrane tr... 3 | 3
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
Solute carrier family 12 member 6 SLC12A6 Tbio Transporter -1.73943 58.4 161
Potassium voltage-gated channel subfamily A member 1 KCNA1 Tclin Ion Channel -2.59564 379.1 313