Development Level

Tbio 24 | 10,625
Tchem 7 | 1,890
Tclin 6 | 602
Tdark 1 | 7,003

Collection

Eligible Ion Channel Proteins 9 | 117

IMPC Term

decreased body weight 2 | 174
preweaning lethality, incomple... 2 | 260
abnormal behavior 1 | 226
abnormal head morphology 1 | 10
abnormal retina morphology 1 | 100
absent startle reflex 1 | 15
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased circulating fructosa... 1 | 31
decreased circulating iron lev... 1 | 25
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased prepulse inhibition 1 | 52
decreased startle reflex 1 | 48
decreased total body fat amoun... 1 | 186
hypoactivity 1 | 89
increased circulating alanine ... 1 | 11
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating fructosa... 1 | 11
increased circulating iron lev... 1 | 25
increased circulating magnesiu... 1 | 10
increased or absent threshold ... 1 | 128

Disease

medulloblastoma, large-cell 22 | 6,234
ovarian cancer 19 | 8,484
atypical teratoid / rhabdoid tumor 18 | 4,369
oligodendroglioma 17 | 2,849
osteosarcoma 17 | 7,933
glioblastoma 15 | 5,572
psoriasis 15 | 6,685
Pick disease 13 | 1,893
primitive neuroectodermal tumor 12 | 3,031
ependymoma 10 | 2,514
lung cancer 10 | 4,466
pilocytic astrocytoma 10 | 3,086
medulloblastoma 9 | 1,524
pediatric high grade glioma 9 | 2,712
astrocytic glioma 8 | 2,241
colon cancer 8 | 1,475
ductal carcinoma in situ 8 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
malignant mesothelioma 8 | 3,162
subependymal giant cell astrocytoma 8 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
invasive ductal carcinoma 7 | 2,950
lung carcinoma 7 | 2,844
posterior fossa group A ependymoma 7 | 1,511
Breast cancer 6 | 3,094
Long QT syndrome 6 | 52
adult high grade glioma 6 | 2,148
group 4 medulloblastoma 6 | 1,875
interstitial cystitis 6 | 2,299
non-small cell lung cancer 6 | 2,798
pituitary cancer 6 | 1,972
ulcerative colitis 6 | 2,087
Atrial Fibrillation 5 | 110
Bipolar Disorder 5 | 266
Cancer 5 | 2,346
Carcinoma 5 | 2,147
Down syndrome 5 | 548
astrocytoma 5 | 1,493
group 3 medulloblastoma 5 | 2,254
lung adenocarcinoma 5 | 2,713
Attention deficit hyperactivity disorder 4 | 156
Hypertension 4 | 287
Multiple myeloma 4 | 1,327
Parkinson's disease 4 | 364
Schizophrenia 4 | 501
active Crohn's disease 4 | 918
breast carcinoma 4 | 1,614
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
sonic hedgehog group medulloblastoma 4 | 1,482
Amyotrophic Lateral Sclerosis 3 | 431
Brugada syndrome 3 | 26
Child Development Disorders, Pervasive 3 | 55
Chromosome 1p36 deletion syndrome 3 | 24
Eaton-Lambert syndrome 3 | 40
Epilepsy 3 | 346
Heart disease 3 | 279
Hypertensive disease 3 | 193
Hypertensive disorder 3 | 58
Multiple Sclerosis 3 | 498
Romano-Ward Syndrome 3 | 12
acute myeloid leukemia 3 | 780
adrenocortical carcinoma 3 | 1,427
cystic fibrosis 3 | 1,665
pancreatic cancer 3 | 2,300
posterior fossa group B ependymoma 3 | 1,530
spina bifida 3 | 1,064
Acromegaly 2 | 40
Alcohol dependence 2 | 107
Allergic rhinitis 2 | 91
Alzheimer's disease 2 | 644
Amphetamine-Related Disorders 2 | 74
Autistic Disorder 2 | 320
Cardiomyopathies 2 | 90
Chronic obstructive pulmonary disease 2 | 146
Cleft palate 2 | 125
Delusional disorder 2 | 10
Endometriosis 2 | 535
Familial atrial fibrillation 2 | 16
Gout 2 | 93
Heroin dependence 2 | 30
Itching of skin 2 | 19
Major Depressive Disorder 2 | 106
Motor neuron disease 2 | 39
Muscle Weakness 2 | 92
Neurodegenerative disease 2 | 383
Parkinson Disease 2 | 102
Pathological gambling 2 | 16
Prostatic Neoplasms 2 | 471
Restless legs 2 | 5
Schizoaffective disorder 2 | 33
active ulcerative colitis 2 | 477
acute quadriplegic myopathy 2 | 1,157
atypical teratoid/rhabdoid tumor 2 | 1,095
fibroadenoma 2 | 557
hereditary spastic paraplegia 2 | 313
interstitial lung disease 2 | 291
non-inflammatory breast cancer 2 | 208
non-small cell lung carcinoma 2 | 413
tuberculosis 2 | 1,557

Tissue

Blood and immune system 38 | 17,995
Liver and Pancreas 38 | 18,136
Nervous System 38 | 18,561
Cardiovascular System 37 | 17,958
Digestive Tract 37 | 18,473
Endocrine System 37 | 18,512
Female tissues 37 | 18,647
Respiratory system 37 | 17,484
Skin and soft tissues 37 | 18,115
Urinary Tract 37 | 18,444
Male tissues 36 | 17,969

Target Family

Ion Channel 18 | 341
Non-IDG 7 | 11,971
Enzyme 4 | 4,146
Kinase 4 | 634
GPCR 3 | 406
Transcription Factor 1 | 1,400
Transporter 1 | 473

GO Function

potassium channel regulator ac... 38 | 38
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
D(2) dopamine receptor DRD2 Tclin GPCR -3.24474 1775.2 248
Small ubiquitin-related modifier 1 SUMO1 Tbio Non-IDG -2.69547 474.2 685
Voltage-gated potassium channel subunit beta-3 KCNAB3 Tdark Ion Channel -0.68945 4.88 108
E3 SUMO-protein ligase PIAS3 PIAS3 Tbio Transcription Factor -1.69960 50.8 156
Potassium voltage-gated channel subfamily E member 1 KCNE1 Tbio Ion Channel -2.63112 407.4 169
Potassium voltage-gated channel subfamily E member 3 KCNE3 Tbio Ion Channel -1.61411 39.3 71
Potassium voltage-gated channel subfamily E member 2 KCNE2 Tbio Ion Channel -1.96950 86.9 104
Leucine-rich repeat-containing protein 26 LRRC26 Tbio Ion Channel -0.94283 9.25 70
14-3-3 protein epsilon YWHAE Tchem Non-IDG -2.18406 158.6 309
Disks large homolog 1 DLG1 Tbio Non-IDG -2.17402 165.0 183