Development Level

Tbio 15 | 10,625
Tclin 15 | 602
Tdark 3 | 7,003
Tchem 2 | 1,890

Collection

Eligible Ion Channel Proteins 7 | 117

IMPC Term

abnormal behavior 1 | 226
abnormal epididymis morphology 1 | 31
decreased bone mineral content 1 | 157
decreased grip strength 1 | 123
enlarged epididymis 1 | 27
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
increased circulating alkaline... 1 | 119
increased circulating total pr... 1 | 20

Disease

medulloblastoma, large-cell 17 | 6,234
glioblastoma 16 | 5,572
pilocytic astrocytoma 15 | 3,086
atypical teratoid / rhabdoid tumor 14 | 4,369
osteosarcoma 13 | 7,933
primitive neuroectodermal tumor 12 | 3,031
oligodendroglioma 11 | 2,849
adult high grade glioma 10 | 2,148
Carcinoma 9 | 2,147
posterior fossa group A ependymoma 9 | 1,511
subependymal giant cell astrocytoma 9 | 2,287
Eaton-Lambert syndrome 8 | 40
Epilepsy 8 | 346
Multiple Sclerosis 8 | 498
astrocytic glioma 8 | 2,241
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
lung carcinoma 8 | 2,844
malignant mesothelioma 8 | 3,162
ovarian cancer 8 | 8,484
psoriasis 8 | 6,685
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
lung adenocarcinoma 7 | 2,713
pediatric high grade glioma 7 | 2,712
Pick disease 6 | 1,893
lung cancer 6 | 4,466
medulloblastoma 6 | 1,524
cystic fibrosis 5 | 1,665
ependymoma 5 | 2,514
group 3 medulloblastoma 5 | 2,254
invasive ductal carcinoma 5 | 2,950
sonic hedgehog group medulloblastoma 5 | 1,482
Breast cancer 4 | 3,094
General anesthesia 4 | 53
Intellectual disability 4 | 573
active Crohn's disease 4 | 918
non-small cell lung cancer 4 | 2,798
pancreatic cancer 4 | 2,300
posterior fossa group B ependymoma 4 | 1,530
primary pancreatic ductal adenocarcinoma 4 | 1,271
Alzheimer's disease 3 | 644
Diabetes Mellitus, Non-Insulin-Dependent 3 | 157
Episodic ataxia 3 | 17
Long QT syndrome 3 | 52
Partial Epilepsy Treatment Adjunct 3 | 16
astrocytoma 3 | 1,493
atypical teratoid/rhabdoid tumor 3 | 1,095
breast carcinoma 3 | 1,614
colon cancer 3 | 1,475
ductal carcinoma in situ 3 | 1,745
gastric carcinoma 3 | 832
group 4 medulloblastoma 3 | 1,875
interstitial cystitis 3 | 2,299
non-inflammatory breast cancer 3 | 208
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
pituitary cancer 3 | 1,972
ulcerative colitis 3 | 2,087
Atrial Fibrillation 2 | 110
Benign neonatal seizures 2 | 4
Brain Ischemia 2 | 87
Conn's syndrome 2 | 22
Decreased respiratory function 2 | 2
Dentin sensitivity 2 | 14
Down syndrome 2 | 548
Early infantile epileptic encephalopathy with suppression bursts 2 | 18
Endometriosis 2 | 535
Familial benign neonatal epilepsy 2 | 2
Fragile X syndrome 2 | 31
Gingival recession 2 | 14
Hyperaldosteronism 2 | 27
Hypertensive disorder 2 | 58
Kidney disease 2 | 396
Migraine 2 | 79
Migraine Disorders 2 | 26
Post-Anesthesia Respiratory Depression 2 | 2
Seizures 2 | 95
Type 2 diabetes mellitus 2 | 189
Vascular disease 2 | 281
active ulcerative colitis 2 | 477
adrenocortical carcinoma 2 | 1,427
progressive supranuclear palsy 2 | 674
Brain edema 1 | 26
Central sleep apnea 1 | 12
Cocaine dependence 1 | 24
Developmental Disabilities 1 | 20
Developmental coordination disorder 1 | 8
Gliosis 1 | 16
Hyperglycemia 1 | 120
Hypertrichosis 1 | 23
Language Development Disorders 1 | 9
Leiomyosarcoma 1 | 19
Meniere's disease 1 | 24
Noise-induced hearing loss 1 | 5
Oligohydramnios 1 | 18
Pain 1 | 70
Patellofemoral pain syndrome 1 | 9
Pityriasis versicolor 1 | 18
Polyhydramnios 1 | 29
Sickle cell anemia 1 | 35
maturity-onset diabetes of the young 1 | 28

Tissue

Digestive Tract 35 | 18,473
Endocrine System 35 | 18,512
Female tissues 35 | 18,647
Nervous System 35 | 18,561
Urinary Tract 35 | 18,444
Cardiovascular System 34 | 17,958
Liver and Pancreas 34 | 18,136
Male tissues 34 | 17,969
Respiratory system 33 | 17,484
Skin and soft tissues 33 | 18,115
Blood and immune system 32 | 17,995

Target Family

Ion Channel 32 | 341
Transporter 2 | 473
Non-IDG 1 | 11,971

GO Function

potassium channel activity 35 | 35
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 Tchem Ion Channel -2.38460 284.0 184
ATP-binding cassette sub-family C member 8 ABCC8 Tclin Transporter -2.87986 827.3 168
Potassium voltage-gated channel subfamily A member 1 KCNA1 Tclin Ion Channel -2.56457 365.5 298
Aquaporin-1 AQP1 Tbio Non-IDG -3.04203 1040.5 321
Trimeric intracellular cation channel type B TMEM38B Tbio Ion Channel -1.36284 23.4 53
Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 Tclin Ion Channel -2.06206 100.5 99
Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 Tclin Ion Channel -2.58793 412.9 187
Kv channel-interacting protein 1 KCNIP1 Tbio Ion Channel -1.47020 31.4 205
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.51901 324.2 196
Polycystin-2 PKD2 Tbio Ion Channel -2.65714 491.3 218