Development Level

Tbio 23 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

increased mean corpuscular vol... 2 | 92
thrombocytosis 2 | 27
abnormal bone mineralization 1 | 38
abnormal coat- hair morphology 1 | 19
abnormal gait 1 | 69
abnormal hair texture 1 | 4
cataract 1 | 92
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating potassiu... 1 | 20
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
hypoactivity 1 | 132
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating thyroxin... 1 | 7
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean platelet volume 1 | 45
long tibia 1 | 25
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 21 | 11,493
osteosarcoma 15 | 7,950
ovarian cancer 15 | 8,520
lung cancer 9 | 4,740
malignant mesothelioma 8 | 3,232
psoriasis 8 | 6,694
medulloblastoma, large-cell 7 | 6,241
atypical teratoid / rhabdoid tumor 6 | 5,112
glioblastoma 6 | 5,792
group 3 medulloblastoma 6 | 4,104
Multiple myeloma 5 | 1,332
astrocytoma 5 | 1,146
Breast cancer 4 | 3,578
Cancer 4 | 2,499
Neurodegenerative disease 4 | 414
adult high grade glioma 4 | 3,801
primitive neuroectodermal tumor 4 | 3,035
Amyotrophic lateral sclerosis 3 | 451
Depressive disorder 3 | 409
Kidney cancer 3 | 2,613
Muscle Weakness 3 | 170
Pick disease 3 | 1,894
Waldenstrons macroglobulinemia 3 | 765
astrocytic glioma 3 | 2,597
ependymoma 3 | 4,679
invasive ductal carcinoma 3 | 2,951
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
tuberculosis 3 | 2,010
Anxiety 2 | 136
Anxiety disease 2 | 113
Aplastic Anemia 2 | 21
Asthma 2 | 385
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Creatine phosphokinase serum increased 2 | 110
Disease Progression 2 | 136
Distal amyotrophy 2 | 51
Dysarthria 2 | 192
Dyspnea 2 | 76
Elevated creatine kinase 2 | 110
Fasciculation, Tongue 2 | 8
Fatigable weakness of respiratory muscles 2 | 28
Fatigable weakness of swallowing muscles 2 | 28
Fatigue 2 | 182
Frontotemporal dementia 2 | 51
Gait abnormality 2 | 135
Generalized muscle weakness 2 | 57
Machado-Joseph disease 2 | 18
Mild Mental Retardation 2 | 70
Mood swings 2 | 77
Muscle Cramp 2 | 55
Muscle Spasticity 2 | 195
Myopathy 2 | 185
Nerve Degeneration 2 | 121
Neuro-degenerative disease 2 | 43
Neurodegenerative Disorders 2 | 79
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Neuropathy 2 | 261
Paget's disease of bone 2 | 36
Pain 2 | 103
Paralysed 2 | 42
Prostatic Neoplasms 2 | 495
Respiratory Failure 2 | 104
Rheumatoid arthritis 2 | 1,191
Short stature 2 | 531
Skeletal muscle atrophy 2 | 139
Stomach Neoplasms 2 | 300
Xeroderma pigmentosum 2 | 43
Xerostomia 2 | 42
active Crohn's disease 2 | 922
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
colon cancer 2 | 1,478
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
hereditary spastic paraplegia 2 | 318
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung carcinoma 2 | 2,843
muscle degeneration 2 | 139
non-small cell lung cancer 2 | 2,890
pituitary cancer 2 | 1,972
spina bifida 2 | 1,074
Apraxias 1 | 27
Back Pain 1 | 7
Ectropion 1 | 38
Excessive tearing 1 | 12
Foot-drop 1 | 27
Gastroenteritis 1 | 41
Irritation - emotion 1 | 68
Lysinuric protein intolerance 1 | 15
Platyspondyly 1 | 56
Psoriatic arthritis 1 | 86
Restlessness 1 | 14
Short hands 1 | 50
Ventricular hypertrophy 1 | 6
Werner syndrome 1 | 29
Winged scapula 1 | 23

Tissue

Blood and immune system 25 | 16,909
Digestive Tract 25 | 17,369
Endocrine System 25 | 18,159
Female tissues 25 | 17,400
Liver and Pancreas 25 | 16,750
Male tissues 25 | 17,142
Nervous System 25 | 16,725
Respiratory system 25 | 16,393
Skin and soft tissues 25 | 17,230
Urinary Tract 25 | 16,678
Cardiovascular System 24 | 15,192

Target Family

Non-IDG 19 | 12,091
Enzyme 5 | 4,145
Epigenetic 1 | 242

GO Function

polyubiquitin modification-dep... 25 | 25
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ubiquilin-1 UBQLN1 Tbio Non-IDG -1.92650 87.0 256
Large proline-rich protein BAG6 BAG6 Tbio Non-IDG -2.75607 556.9 226
Glycogen debranching enzyme AGL Tbio Non-IDG -2.71712 509.7 141
Ubiquilin-4 UBQLN4 Tbio Non-IDG -1.42493 26.7 74
E3 ubiquitin-protein ligase RAD18 RAD18 Tbio Enzyme -2.22905 169.1 271
UV excision repair protein RAD23 homolog B RAD23B Tbio Non-IDG -1.99412 96.8 313
UV excision repair protein RAD23 homolog A RAD23A Tbio Non-IDG -1.57282 35.7 356
Epidermal growth factor receptor substrate 15 EPS15 Tbio Non-IDG -2.28374 174.5 164
E3 ubiquitin-protein ligase DZIP3 DZIP3 Tbio Enzyme -0.24304 1.68 116
BRISC and BRCA1-A complex member 2 BABAM2 Tbio Non-IDG -1.84649 70.2 156