Development Level

Tbio 17 | 11,445
Tdark 2 | 6,588

IMPC Phenotype

decreased total body fat amoun... 2 | 207
increased lean body mass 2 | 172
abnormal bone structure 1 | 187
abnormal nail morphology 1 | 8
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased vertical activity 1 | 208
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating fructosa... 1 | 13
increased circulating serum al... 1 | 22
increased red blood cell distr... 1 | 34

Disease

Carcinoma 18 | 11,493
ovarian cancer 13 | 8,520
Astrocytoma, Pilocytic 11 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
atypical teratoid / rhabdoid tumor 10 | 5,112
lung adenocarcinoma 10 | 2,716
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
psoriasis 9 | 6,694
ependymoma 8 | 4,679
glioblastoma 8 | 5,792
Breast cancer 7 | 3,578
cystic fibrosis 7 | 1,696
medulloblastoma, large-cell 7 | 6,241
pituitary cancer 7 | 1,972
Kidney cancer 6 | 2,613
invasive ductal carcinoma 6 | 2,951
osteosarcoma 6 | 7,950
Atopic dermatitis 5 | 952
active Crohn's disease 5 | 922
adult high grade glioma 5 | 3,801
astrocytic glioma 5 | 2,597
ductal carcinoma in situ 5 | 1,745
group 3 medulloblastoma 5 | 4,104
group 4 medulloblastoma 5 | 1,855
lung cancer 5 | 4,740
malignant mesothelioma 5 | 3,232
non-small cell lung cancer 5 | 2,890
primitive neuroectodermal tumor 5 | 3,035
breast carcinoma 4 | 1,638
interstitial cystitis 4 | 2,312
oligodendroglioma 4 | 2,850
pancreatic cancer 4 | 2,398
Multiple myeloma 3 | 1,332
active ulcerative colitis 3 | 764
esophageal adenocarcinoma 3 | 737
facioscapulohumeral dystrophy 3 | 288
fibroadenoma 3 | 559
lung carcinoma 3 | 2,843
nasopharyngeal carcinoma 3 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
subependymal giant cell astrocytoma 3 | 2,287
Barrett's esophagus 2 | 182
Bilateral breast cancer 2 | 2
Melanoma 2 | 711
Pick disease 2 | 1,894
Waldenstrons macroglobulinemia 2 | 765
Williams-Beuren syndrome 2 | 50
astrocytoma 2 | 1,146
atypical teratoid/rhabdoid tumor 2 | 357
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
diabetes mellitus 2 | 1,728
pediatric high grade glioma 2 | 1,064
spina bifida 2 | 1,074
Acquired immunodeficiency syndrome 1 | 197
Acquired metabolic disease 1 | 336
Angelman syndrome 1 | 34
Astigmatism 1 | 54
Band keratopathy 1 | 5
Brachydactyly 1 | 156
Calcific tendinitis 1 | 8
Cardiovascular system disease 1 | 246
Carpal tunnel syndrome 1 | 20
Chondroma 1 | 15
Colorectal Neoplasms 1 | 243
Essential Hypertension 1 | 94
Gorham's disease 1 | 4
Heart disease 1 | 306
Hepatomegaly 1 | 285
Hyperparathyroidism 1 | 48
Hyperphosphatemia 1 | 32
Hypophosphatemia 1 | 40
Kidney Failure 1 | 111
Lipid metabolism disorder 1 | 114
Mental Depression 1 | 333
Metabolic syndrome X 1 | 52
Orofacial cleft 1 | 54
Osteomalacia 1 | 35
Osteoporosis 1 | 363
Prostatic Neoplasms 1 | 495
Pseudoxanthoma elasticum 1 | 18
Rickets 1 | 49
Skin cancer 1 | 469
Type 2 diabetes mellitus 1 | 272
Visceral heterotaxy 1 | 14
X-linked cerebral adrenoleukodystrophy 1 | 116
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
aldosterone-producing adenoma 1 | 665
chronic rhinosinusitis 1 | 512
dermatomyositis 1 | 966
inflammatory breast cancer 1 | 286
interstitial lung disease 1 | 298
juvenile dermatomyositis 1 | 1,187
medulloblastoma 1 | 720
non-small cell lung carcinoma 1 | 317
pancreatic carcinoma 1 | 562
posterior fossa group A ependymoma 1 | 468
progressive supranuclear palsy 1 | 676

Tissue

Blood and immune system 19 | 16,909
Digestive Tract 19 | 17,369
Endocrine System 19 | 18,159
Female tissues 19 | 17,400
Liver and Pancreas 19 | 16,750
Male tissues 19 | 17,142
Nervous System 19 | 16,725
Respiratory system 19 | 16,393
Skin and soft tissues 19 | 17,230
Urinary Tract 19 | 16,678
Cardiovascular System 15 | 15,192

Target Family

Enzyme 19 | 4,145

GO Function

polypeptide N-acetylgalactosam... 19 | 19
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..