Development Level

Tbio 14 | 10,625
Tdark 5 | 7,003

IMPC Term

decreased KLRG1-positive NK ce... 1 | 9
decreased Ly6C low monocyte nu... 1 | 23
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating serum al... 1 | 79
decreased grip strength 1 | 123
increased Ly6C high monocyte n... 1 | 12
increased circulating fructosa... 1 | 11
increased neutrophil cell numb... 1 | 15
increased red blood cell distr... 1 | 21
short tibia 1 | 82

Disease

ovarian cancer 13 | 8,484
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,956
pilocytic astrocytoma 11 | 3,086
lung adenocarcinoma 10 | 2,713
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,289
psoriasis 9 | 6,685
atypical teratoid / rhabdoid tumor 8 | 4,369
glioblastoma 8 | 5,572
cystic fibrosis 7 | 1,665
medulloblastoma, large-cell 7 | 6,234
pituitary cancer 7 | 1,972
Breast cancer 6 | 3,094
invasive ductal carcinoma 6 | 2,950
osteosarcoma 6 | 7,933
posterior fossa group A ependymoma 6 | 1,511
Atopic dermatitis 5 | 944
active Crohn's disease 5 | 918
ductal carcinoma in situ 5 | 1,745
group 4 medulloblastoma 5 | 1,875
malignant mesothelioma 5 | 3,162
primitive neuroectodermal tumor 5 | 3,031
astrocytic glioma 4 | 2,241
atypical teratoid/rhabdoid tumor 4 | 1,095
breast carcinoma 4 | 1,614
group 3 medulloblastoma 4 | 2,254
interstitial cystitis 4 | 2,299
lung cancer 4 | 4,466
non-small cell lung cancer 4 | 2,798
oligodendroglioma 4 | 2,849
pancreatic cancer 4 | 2,300
pediatric high grade glioma 4 | 2,712
Bilateral breast cancer 3 | 4
Carcinoma 3 | 2,147
Multiple myeloma 3 | 1,327
adult high grade glioma 3 | 2,148
astrocytoma 3 | 1,493
esophageal adenocarcinoma 3 | 737
facioscapulohumeral dystrophy 3 | 286
fibroadenoma 3 | 557
lung carcinoma 3 | 2,844
nasopharyngeal carcinoma 3 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
subependymal giant cell astrocytoma 3 | 2,287
Barrett's esophagus 2 | 183
IGA Glomerulonephritis 2 | 454
Pick disease 2 | 1,893
Waldenstrons macroglobulinemia 2 | 765
Williams-Beuren syndrome 2 | 45
active ulcerative colitis 2 | 477
colon cancer 2 | 1,475
cutaneous lupus erythematosus 2 | 1,056
diabetes mellitus 2 | 1,663
non-small cell lung carcinoma 2 | 413
posterior fossa group B ependymoma 2 | 1,530
spina bifida 2 | 1,064
ulcerative colitis 2 | 2,087
Acquired metabolic disease 1 | 267
Angelman syndrome 1 | 38
Band keratopathy 1 | 4
Brachydactyly 1 | 52
Calcific tendinitis 1 | 7
Calcinosis 1 | 62
Cardiovascular system disease 1 | 194
Carpal tunnel syndrome 1 | 19
Chondroma 1 | 12
Colorectal Neoplasms 1 | 217
Essential Hypertension 1 | 82
Gorham's disease 1 | 3
Hyperparathyroidism 1 | 43
Hyperphosphatemia 1 | 32
Hypophosphatemia 1 | 31
Lipid metabolism disorder 1 | 102
Mental depression 1 | 58
Metabolic syndrome X 1 | 155
Osteomalacia 1 | 28
Osteoporosis 1 | 257
Primary ciliary dyskinesia 1 | 73
Prostatic Neoplasms 1 | 471
Pseudoxanthoma Elasticum 1 | 19
Pulmonary valve stenosis 1 | 10
Rickets 1 | 42
Schizophrenia 1 | 501
Systemic scleroderma 1 | 66
Type 2 diabetes mellitus 1 | 189
Visceral heterotaxy 1 | 12
X-linked cerebral adrenoleukodystrophy 1 | 115
acute quadriplegic myopathy 1 | 1,157
adrenocortical carcinoma 1 | 1,427
aldosterone-producing adenoma 1 | 664
chronic rhinosinusitis 1 | 512
dermatomyositis 1 | 933
gastric carcinoma 1 | 832
inflammatory breast cancer 1 | 404
interstitial lung disease 1 | 291
juvenile dermatomyositis 1 | 1,189
medulloblastoma 1 | 1,524
pancreatic carcinoma 1 | 567
progressive supranuclear palsy 1 | 674
sonic hedgehog group medulloblastoma 1 | 1,482

Tissue

Blood and immune system 19 | 17,995
Cardiovascular System 19 | 17,958
Digestive Tract 19 | 18,473
Endocrine System 19 | 18,512
Female tissues 19 | 18,647
Liver and Pancreas 19 | 18,136
Male tissues 19 | 17,969
Nervous System 19 | 18,561
Respiratory system 19 | 17,484
Skin and soft tissues 19 | 18,115
Urinary Tract 19 | 18,444

Target Family

Enzyme 19 | 4,146

GO Function

polypeptide N-acetylgalactosam... 19 | 19
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

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