Development Level

Tbio 7 | 10,625

IMPC Phenotype

abnormal clavicle morphology 1 | 5
abnormal rib morphology 1 | 28
decreased circulating triglyce... 1 | 83
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
embryonic lethality prior to o... 1 | 148
increased grip strength 1 | 83
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260

Disease

ovarian cancer 6 | 8,491
medulloblastoma, large-cell 5 | 6,234
osteosarcoma 4 | 7,933
Breast cancer 3 | 3,098
atypical teratoid / rhabdoid tumor 3 | 4,369
dermatomyositis 3 | 966
glioblastoma 3 | 5,572
lung cancer 3 | 4,473
subependymal giant cell astrocytoma 3 | 2,287
Amyotrophic Lateral Sclerosis 2 | 432
Multiple myeloma 2 | 1,327
Neurodegenerative disease 2 | 383
Pick disease 2 | 1,893
Waldenstrons macroglobulinemia 2 | 764
acute quadriplegic myopathy 2 | 1,157
adult high grade glioma 2 | 2,148
astrocytic glioma 2 | 2,241
atypical teratoid/rhabdoid tumor 2 | 1,095
cystic fibrosis 2 | 1,670
ependymoma 2 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
juvenile dermatomyositis 2 | 1,189
malignant mesothelioma 2 | 3,163
non-small cell lung cancer 2 | 2,798
pancreatic cancer 2 | 2,300
pediatric high grade glioma 2 | 2,712
primitive neuroectodermal tumor 2 | 3,031
progressive supranuclear palsy 2 | 674
psoriasis 2 | 6,685
Amenorrhea 1 | 60
Ataxia, Spinocerebellar 1 | 15
Attention deficit hyperactivity disorder 1 | 156
Atypical autism 1 | 25
Autistic Disorder 1 | 320
Autosomal dominant cerebellar ataxia 1 | 34
Brain disease 1 | 84
CHROMOSOME Xq27.3-q28 DUPLICATION SYNDROME 1 | 1
Cerebellar Ataxia 1 | 72
Chromosome 4q21 deletion syndrome 1 | 6
Cognition Disorders 1 | 23
Combined oxidative phosphorylation defect type 13 1 | 1
Combined oxidative phosphorylation deficiency 13 1 | 1
Congenital Abnormality 1 | 11
Craniofacial Abnormalities 1 | 147
DEAFNESS, AUTOSOMAL RECESSIVE 70 1 | 1
Deafness, autosomal recessive, 70 1 | 1
Down syndrome 1 | 548
Duchenne muscular dystrophy 1 | 602
FRAXA Syndrome 1 | 1
Facies 1 | 8
Fragile 10 Mental Retardation Syndrome 1 | 2
Fragile 10 Tremor/Ataxia Syndrome 1 | 1
Fragile X syndrome 1 | 31
Fragile X tremor/ataxia syndrome 1 | 1
Fragile X-associated tremor/ataxia syndrome 1 | 5
Gonadal dysgenesis 1 | 6
Infertility 1 | 163
Intellectual disability 1 | 573
LIMB-GIRDLE MUSCULAR DYSTROPHY, TYPE 1G (disorder) 1 | 1
Learning disability 1 | 20
Limb-girdle muscular dystrophy 1G 1 | 1
Liver carcinoma 1 | 217
Mucopolysaccharidosis II 1 | 5
Nonsyndromic deafness 1 | 121
Ovarian Failure, Premature 1 | 6
Ovarian dysfunction 1 | 19
Premature ovarian failure 1 | 64
Premature ovarian failure 1 1 | 2
Primary Ovarian Insufficiency, Fragile X-Associated 1 | 1
Rett syndrome 1 | 18
Rheumatoid Arthritis 1 | 1,170
Schizophrenia 1 | 503
Spinocerebellar ataxia type 1 1 | 16
Xq27.3q28 duplication syndrome 1 | 1
adrenocortical carcinoma 1 | 1,427
astrocytoma 1 | 1,493
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 499
autosomal dominant limb-girdle muscular dystrophy type 1G 1 | 1
chronic lymphocytic leukemia 1 | 244
gastric cancer 1 | 436
group 3 medulloblastoma 1 | 2,254
group 4 medulloblastoma 1 | 1,875
hepatocellular carcinoma 1 | 550
inflammatory breast cancer 1 | 404
interstitial lung disease 1 | 292
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,289
invasive ductal carcinoma 1 | 2,950
limb-girdle muscular dystrophy 1 | 36
lung adenocarcinoma 1 | 2,714
medulloblastoma 1 | 1,524
nasopharyngeal carcinoma 1 | 1,056
pancreatic carcinoma 1 | 567
pilocytic astrocytoma 1 | 3,086
primary pancreatic ductal adenocarcinoma 1 | 1,271
sarcoidosis 1 | 368
sonic hedgehog group medulloblastoma 1 | 1,482
spina bifida 1 | 1,064
tuberculosis 1 | 1,563
tuberculosis and treatment for 3 months 1 | 327

Tissue

Blood and immune system 7 | 17,994
Cardiovascular System 7 | 17,957
Digestive Tract 7 | 18,472
Endocrine System 7 | 18,511
Female tissues 7 | 18,646
Liver and Pancreas 7 | 18,135
Male tissues 7 | 17,968
Nervous System 7 | 18,560
Respiratory system 7 | 17,483
Skin and soft tissues 7 | 18,114
Urinary Tract 7 | 18,443

Target Family

Non-IDG 5 | 11,969
Enzyme 1 | 4,146
Epigenetic 1 | 242

GO Function

poly(G) binding 7 | 7
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine-threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ataxin-1 ATXN1 Tbio Non-IDG -2.27547 200.4 549
Heterogeneous nuclear ribonucleoprotein D-like HNRNPDL Tbio Non-IDG -1.02289 11.1 87
Synaptic functional regulator FMR1 FMR1 Tbio Epigenetic -3.36032 2331.5 449
Heterogeneous nuclear ribonucleoprotein U HNRNPU Tbio Non-IDG -2.29541 191.0 158
Polyribonucleotide nucleotidyltransferase 1, mitochondrial PNPT1 Tbio Enzyme -2.37396 233.0 176
Microspherule protein 1 MCRS1 Tbio Non-IDG -1.40374 31.3 80
Protein PAT1 homolog 1 PATL1 Tbio Non-IDG -0.79433 7.69 58