Development Level

Tbio 9 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

embryonic lethality prior to o... 2 | 239
preweaning lethality, complete... 2 | 979
decreased caudal vertebrae num... 1 | 53
embryonic lethality prior to t... 1 | 278
increased fasted circulating g... 1 | 76
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 7 | 11,493
osteosarcoma 7 | 7,950
ovarian cancer 5 | 8,520
group 3 medulloblastoma 4 | 4,104
psoriasis 4 | 6,694
ependymoma 3 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
oligodendroglioma 3 | 2,850
Breast cancer 2 | 3,578
Dental caries 2 | 164
astrocytic glioma 2 | 2,597
atypical teratoid/rhabdoid tumor 2 | 357
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung cancer 2 | 4,740
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
Abnormal blistering of the skin 1 | 54
Abnormal pigmentation 1 | 25
Abnormality of female internal genitalia 1 | 13
Abnormality of the fingernails 1 | 51
Abnormality of the pharynx 1 | 19
Adult onset 1 | 82
Alopecia 1 | 115
Anemia 1 | 365
Anorectal Malformations 1 | 8
Aplasia/Hypoplasia of the skin 1 | 16
Bipolar I disorder 1 | 23
Blister of skin 1 | 54
Blood Coagulation Disorders 1 | 42
Bone marrow hypocellularity 1 | 20
Candidiasis 1 | 55
Cataract 7 1 | 32
Cellular immunodeficiency 1 | 17
Cerebral atrophy 1 | 178
Chemical and Drug Induced Liver Injury 1 | 195
Cholestasis 1 | 155
Coagulation abnormalities 1 | 27
Decreased platelet count 1 | 111
Dental fluorosis 1 | 20
Dilated ventricles (finding) 1 | 121
Dyskeratosis congenita 1 | 24
Dystrophia unguium 1 | 53
Esophageal Stenosis 1 | 15
Failure to gain weight 1 | 365
Frequent fractures 1 | 53
Gingival Diseases 1 | 19
Hemoglobin low 1 | 124
Hemorrhagic Disorders 1 | 30
Hyperhidrosis disorder 1 | 81
Hyperpigmented macules 1 | 42
Hypodontia 1 | 81
Hypoplastic-absent toenails 1 | 11
Idiopathic pulmonary fibrosis 1 | 23
Immunologic Deficiency Syndromes 1 | 113
Increased fracture rate 1 | 53
Increased sweating 1 | 81
Infantile onset 1 | 238
Large elongated pulp chamber 1 | 14
Leukokeratosis 1 | 19
Leukoplakia, Oral 1 | 20
Liver Cirrhosis, Experimental 1 | 769
Lyme disease 1 | 26
Malabsorption 1 | 82
Male infertility 1 | 206
Microphthalmia with limb anomalies 1 | 40
Muscle Hypertonia 1 | 88
Neurodegenerative disease 1 | 414
Neutrophil abnormality 1 | 20
Pediatric failure to thrive 1 | 365
Periodontal Diseases 1 | 21
Pharyngitis 1 | 17
Pontocerebellar hypoplasia 1 | 36
Pulmonary Fibrosis 1 | 106
Recurrent respiratory infections 1 | 141
Rotting teeth 1 | 73
Rough bone trabeculation 1 | 11
Schizoaffective Disorder 1 | 55
Skin Ulcer 1 | 48
Skin bulla 1 | 54
Sparse hair 1 | 59
Sparse scalp hair 1 | 42
Sweating 1 | 81
Taurodontism 1 | 14
Telangiectasia of the skin 1 | 39
Thin, sparse hair 1 | 59
Thrombocytopenia 1 | 197
Tracheoesophageal Fistula 1 | 36
Urethral Stricture 1 | 18
Varying degree of multiple fractures 1 | 53
Waldenstrons macroglobulinemia 1 | 765
acute quadriplegic myopathy 1 | 1,158
astrocytoma 1 | 1,146
hypopigmented skin patch 1 | 59
pancreatic carcinoma 1 | 562
progressive supranuclear palsy 1 | 676
tuberculosis 1 | 2,010
tuberculosis and treatment for 3 months 1 | 179
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 10 | 16,909
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Cardiovascular System 9 | 15,192
Urinary Tract 9 | 16,678

Target Family

Non-IDG 6 | 12,091
Enzyme 4 | 4,145

GO Function

poly(A)-specific ribonuclease ... 10 | 10
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
2',5'-phosphodiesterase 12 PDE12 Tbio Enzyme -1.46115 31.6 90
Target of EGR1 protein 1 TOE1 Tbio Non-IDG -1.37536 23.1 140
CCR4-NOT transcription complex subunit 8 CNOT8 Tbio Non-IDG -2.83783 687.5 209
CCR4-NOT transcription complex subunit 6-like CNOT6L Tbio Non-IDG -0.89586 7.91 51
Poly(A)-specific ribonuclease PNLDC1 PNLDC1 Tbio Enzyme -0.61101 2.88 60
PAN2-PAN3 deadenylation complex catalytic subunit PAN2 PAN2 Tbio Enzyme -0.66901 4.14 87
CCR4-NOT transcription complex subunit 7 CNOT7 Tchem Non-IDG -1.18731 15.5 147
Nocturnin NOCT Tbio Non-IDG -1.84562 69.3 92
CCR4-NOT transcription complex subunit 6 CNOT6 Tbio Non-IDG -1.27015 19.4 125
Poly(A)-specific ribonuclease PARN PARN Tbio Enzyme -1.87605 76.4 263