Development Level

Tbio 15 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal spine curvature 1 | 9
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased heart weight 1 | 62
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 14 | 11,493
ovarian cancer 14 | 8,520
lung cancer 12 | 4,740
medulloblastoma, large-cell 10 | 6,241
osteosarcoma 9 | 7,950
group 3 medulloblastoma 8 | 4,104
lung adenocarcinoma 8 | 2,716
atypical teratoid / rhabdoid tumor 7 | 5,112
glioblastoma 7 | 5,792
primitive neuroectodermal tumor 7 | 3,035
psoriasis 7 | 6,694
Breast cancer 6 | 3,578
Multiple myeloma 6 | 1,332
Pick disease 6 | 1,894
acute quadriplegic myopathy 6 | 1,158
astrocytoma 6 | 1,146
invasive ductal carcinoma 6 | 2,951
dermatomyositis 5 | 966
ependymoma 5 | 4,679
progressive supranuclear palsy 5 | 676
Waldenstrons macroglobulinemia 4 | 765
adrenocortical carcinoma 4 | 1,428
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
spina bifida 4 | 1,074
Amyotrophic lateral sclerosis 3 | 451
Intellectual disability 3 | 1,016
Kidney cancer 3 | 2,613
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
atypical teratoid/rhabdoid tumor 3 | 357
breast carcinoma 3 | 1,638
ductal carcinoma in situ 3 | 1,745
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
juvenile dermatomyositis 3 | 1,187
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Adult onset 2 | 82
Autosomal recessive predisposition 2 | 1,442
Cancer 2 | 2,499
Down syndrome 2 | 499
Duchenne muscular dystrophy 2 | 601
Microcephaly 2 | 166
Myopathy 2 | 185
Rimmed vacuoles on biopsy 2 | 15
Slow progression 2 | 89
Spinal muscular atrophy 2 | 34
active Crohn's disease 2 | 922
aldosterone-producing adenoma 2 | 665
colon cancer 2 | 1,478
diabetes mellitus 2 | 1,728
hepatocellular carcinoma 2 | 547
hereditary spastic paraplegia 2 | 318
interstitial lung disease 2 | 298
non primary Sjogren syndrome sicca 2 | 891
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
relapsing-remitting multiple sclerosis 2 | 18
subependymal giant cell astrocytoma 2 | 2,287
Acquired immunodeficiency syndrome 1 | 197
Adenocarcinoma of lung 1 | 142
Breast Neoplasms 1 | 445
COPD 1 | 118
Carcinoma, Transitional Cell 1 | 32
Cardiovascular system disease 1 | 246
Cataract 7 1 | 32
Celiac disease 1 | 116
Congenital clubfoot 1 | 109
Degenerative polyarthritis 1 | 115
Disease Models, Animal 1 | 155
Distal amyotrophy 1 | 51
Fibromyalgia 1 | 19
Fragile X syndrome 1 | 34
Gaucher disease type 1 1 | 180
Gaucher disease type 3 1 | 67
Hyperplasia of nose 1 | 23
Hypertrophy of nose 1 | 23
Large nose 1 | 23
Lymphocytic gastritis 1 | 4
Lymphoma 1 | 81
Mammary Neoplasms 1 | 425
Microretrognathia 1 | 13
Microstomia 1 | 78
Mildly increased creatine kinase 1 | 20
Osteoarthritis 1 | 184
Osteoporosis 1 | 363
Prominent ear 1 | 56
Protruding ears 1 | 56
Retinitis pigmentosa 25 1 | 9
Rift Valley fever 1 | 14
Skin disease 1 | 66
X- linked recessive 1 | 110
X-linked dominant 1 | 57
limb-girdle muscular dystrophy 1 | 37
non-small cell lung carcinoma 1 | 317

Tissue

Blood and immune system 16 | 16,909
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Cardiovascular System 15 | 15,192
Female tissues 15 | 17,400
Respiratory system 15 | 16,393

Target Family

Non-IDG 14 | 12,091
Enzyme 2 | 4,145

GO Function

poly(A) binding 16 | 16
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-dependent RNA helicase DDX3X DDX3X Tchem Enzyme -2.32036 221.7 479
Nucleolysin TIA-1 isoform p40 TIA1 Tbio Non-IDG -2.86461 714.2 314
RNA-binding protein with multiple splicing RBPMS Tbio Non-IDG -2.12771 131.9 266
KH domain-containing, RNA-binding, signal transduction-associated protein 1 KHDRBS1 Tbio Non-IDG -2.10965 158.1 231
Heterogeneous nuclear ribonucleoprotein Q SYNCRIP Tbio Non-IDG -1.66106 45.3 189
ATP-dependent RNA helicase DDX1 DDX1 Tbio Enzyme -1.66212 44.8 174
Heterogeneous nuclear ribonucleoprotein U HNRNPU Tbio Non-IDG -2.33813 207.8 169
Eukaryotic initiation factor 4A-III EIF4A3 Tbio Non-IDG -2.34087 210.7 164
Polyadenylate-binding protein 4 PABPC4 Tbio Non-IDG -0.92422 8.32 150
Polyadenylate-binding protein 1 PABPC1 Tbio Non-IDG -2.55959 365.2 149