Development Level

Tclin 6 | 613
Tbio 5 | 11,445
Tchem 4 | 1,598

IMPC Phenotype

abnormal gait 1 | 69
abnormal maxilla morphology 1 | 17
abnormal seminal vesicle morph... 1 | 114
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
enlarged heart 1 | 210
increased blood urea nitrogen ... 1 | 48
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
preweaning lethality, complete... 1 | 979
thrombocytopenia 1 | 56

Disease

Cancer 15 | 2,499
Carcinoma 13 | 11,493
Breast cancer 11 | 3,578
ovarian cancer 11 | 8,520
malignant mesothelioma 10 | 3,232
osteosarcoma 10 | 7,950
lung cancer 9 | 4,740
pancreatic cancer 9 | 2,398
cystic fibrosis 8 | 1,696
glioblastoma 8 | 5,792
interstitial cystitis 8 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
invasive ductal carcinoma 8 | 2,951
lung carcinoma 8 | 2,843
psoriasis 8 | 6,694
medulloblastoma, large-cell 7 | 6,241
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung adenocarcinoma 6 | 2,716
oligodendroglioma 6 | 2,850
tuberculosis 6 | 2,010
Liver Cirrhosis, Experimental 5 | 769
atypical teratoid / rhabdoid tumor 5 | 5,112
breast carcinoma 5 | 1,638
colon cancer 5 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
Astrocytoma, Pilocytic 4 | 3,081
Atherosclerosis 4 | 291
Epilepsy 4 | 792
Kidney cancer 4 | 2,613
acute quadriplegic myopathy 4 | 1,158
adrenocortical carcinoma 4 | 1,428
dermatomyositis 4 | 966
ductal carcinoma in situ 4 | 1,745
gastric carcinoma 4 | 807
juvenile dermatomyositis 4 | 1,187
non-small cell lung cancer 4 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
primary pancreatic ductal adenocarcinoma 4 | 1,109
ulcerative colitis 4 | 1,819
Adult onset 3 | 82
Anemia 3 | 365
Asthma 3 | 385
Coronary artery disease 3 | 268
Depressive disorder 3 | 409
Endometriosis 3 | 540
Haemorrhage subcutaneous 3 | 10
Hepatomegaly 3 | 285
Lung diseases 3 | 50
Lymphedema 3 | 42
Multiple, subcutaneous nodules 3 | 53
Proliferative vitreoretinopathy 3 | 17
Prostatic Neoplasms 3 | 495
Renal Cell Carcinoma 3 | 214
Reperfusion Injury 3 | 86
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
Seizures 3 | 596
Squamous cell carcinoma 3 | 129
Subcutaneous nodule 3 | 53
Thrombocytopenia 3 | 197
adult high grade glioma 3 | 3,801
aldosterone-producing adenoma 3 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
diabetes mellitus 3 | 1,728
group 4 medulloblastoma 3 | 1,855
mucosa-associated lymphoid tissue lymphoma 3 | 484
pancreatic carcinoma 3 | 562
pediatric high grade glioma 3 | 1,064
posterior fossa group A ependymoma 3 | 468
subependymal giant cell astrocytoma 3 | 2,287
Acquired metabolic disease 2 | 336
Athetosis 2 | 16
Autistic Disorder 2 | 364
Bradykinesia 2 | 34
Cardiovascular system disease 2 | 246
Chorea 2 | 29
Clouding of corneal stroma 2 | 50
Congenital Heart Defects 2 | 58
Corneal Opacity 2 | 53
DOID:2627 2 | 94
Dilated ventricles (finding) 2 | 121
Downward slant of palpebral fissure 2 | 158
Dysarthria 2 | 192
Dystonia 2 | 164
Dystonic disease 2 | 106
Endometrial Neoplasms 2 | 55
Gliosis 2 | 56
Hyperreflexia 2 | 209
Malformations of Cortical Development, Group II 2 | 31
Mesothelioma 2 | 38
Myopia 2 | 176
Neoplasm Metastasis 2 | 168
Osteochondrodysplasias 2 | 72
Progressive disorder 2 | 142
Retinal Detachment 2 | 51
Retinal Diseases 2 | 55
Tremor 2 | 113
Urinary Incontinence 2 | 50

Tissue

Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678

Target Family

Non-IDG 9 | 12,091
Kinase 4 | 634
Enzyme 2 | 4,145

GO Function

platelet-derived growth factor... 15 | 15
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Receptor-type tyrosine-protein phosphatase eta PTPRJ Tbio Enzyme -1.98955 114.2 298
Integrin alpha-5 ITGA5 Tbio Non-IDG -2.29130 169.1 826
Platelet-derived growth factor subunit A PDGFA Tchem Non-IDG -2.74845 537.8 341
Platelet-derived growth factor C PDGFC Tbio Non-IDG -2.03910 120.6 226
Vascular endothelial growth factor D VEGFD Tbio Non-IDG -2.45080 283.2 498
Interleukin-1 receptor type 1 IL1R1 Tclin Non-IDG -2.68139 387.6 620
Vascular endothelial growth factor A VEGFA Tclin Non-IDG -4.27197 19076.6 1809
Platelet-derived growth factor subunit B PDGFB Tchem Non-IDG -3.27151 1795.5 434
Serine/threonine-protein kinase/endoribonuclease IRE1 ERN1 Tchem Kinase -2.44644 224.3 489
Platelet-derived growth factor receptor beta PDGFRB Tclin Kinase -2.89315 712.3 1390