Development Level

Tbio 7 | 11,445
Tchem 2 | 1,598
Tclin 2 | 613

IMPC Phenotype

abnormal femur morphology 1 | 14
abnormal seminal vesicle morph... 1 | 114
decreased circulating glucose ... 1 | 126
decreased total body fat amoun... 1 | 207
dilated heart left ventricle 1 | 11
enlarged heart 1 | 210
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 36
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 10 | 11,493
lung cancer 10 | 4,740
Liver Cirrhosis, Experimental 9 | 769
glioblastoma 9 | 5,792
medulloblastoma, large-cell 9 | 6,241
pancreatic cancer 9 | 2,398
Astrocytoma, Pilocytic 8 | 3,081
Breast cancer 8 | 3,578
Kidney cancer 8 | 2,613
atypical teratoid / rhabdoid tumor 8 | 5,112
gastric carcinoma 8 | 807
ovarian cancer 8 | 8,520
Duchenne muscular dystrophy 7 | 601
ependymoma 7 | 4,679
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
lung adenocarcinoma 7 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
primitive neuroectodermal tumor 7 | 3,035
psoriasis 7 | 6,694
Acquired scoliosis 6 | 281
Becker muscular dystrophy 6 | 191
Curvature of spine 6 | 282
adult high grade glioma 6 | 3,801
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
breast carcinoma 6 | 1,638
esophageal adenocarcinoma 6 | 737
interstitial lung disease 6 | 298
non-small cell lung cancer 6 | 2,890
oligodendroglioma 6 | 2,850
osteosarcoma 6 | 7,950
urothelial carcinoma 6 | 318
Cancer 5 | 2,499
Degenerative polyarthritis 5 | 115
Hernia, Inguinal 5 | 89
Hypoplastic mandible condyle 5 | 275
Joint hyperflexibility 5 | 78
Mandibular hypoplasia 5 | 275
Micrognathism 5 | 275
Mitral Valve Prolapse Syndrome 5 | 39
Pectus excavatum 5 | 100
Short stature 5 | 531
Skin hyperelastic 5 | 32
Thin skin 5 | 47
cystic fibrosis 5 | 1,696
invasive ductal carcinoma 5 | 2,951
juvenile dermatomyositis 5 | 1,187
limb girdle muscular dystrophy 2A 5 | 213
malignant mesothelioma 5 | 3,232
nasopharyngeal carcinoma 5 | 1,058
pterygium 5 | 76
ulcerative colitis 5 | 1,819
Abortion, Spontaneous 4 | 109
Acquired flat foot 4 | 72
Autosomal recessive predisposition 4 | 1,442
Congenital clubfoot 4 | 109
Decreased projection of midface 4 | 105
Ecchymosis 4 | 66
Ehlers-Danlos syndrome 4 | 43
Exophthalmos 4 | 112
Fibrosis 4 | 44
Flatfoot 4 | 73
Fragile skin 4 | 18
Hyperkyphosis 4 | 111
Hypotrophic midface 4 | 105
Increased tendency to bruise 4 | 66
Joint laxity 4 | 54
Kyphosis deformity of spine 4 | 114
Midface retrusion 4 | 105
Premature Birth 4 | 77
Premature birth of newborn 4 | 67
Prominent eyes 4 | 96
Prominent globes 4 | 96
Protruding eyes 4 | 96
Pulmonary Fibrosis 4 | 106
Respiratory Insufficiency 4 | 132
Respiratory function loss 4 | 121
Skin cancer 4 | 469
Small midface 4 | 105
Soft skin 4 | 17
Spontaneous abortion 4 | 113
Velvety skin 4 | 17
head and neck cancer and chronic obstructive pulmonary disease 4 | 239
interstitial cystitis 4 | 2,312
pituitary cancer 4 | 1,972
Abnormality of pelvic girdle bone morphology 3 | 37
Atherosclerosis 3 | 291
Congenital Epicanthus 3 | 177
Frontal bossing 3 | 157
Gastroesophageal reflux disease 3 | 110
Heartburn 3 | 78
Liver Cirrhosis 3 | 181
Liver cancer 3 | 604
Melanoma 3 | 711
Myopia 3 | 176
Progressive disorder 3 | 142
Prominent ear 3 | 56
Protruding ears 3 | 56
active Crohn's disease 3 | 922

Tissue

Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678
Blood and immune system 10 | 16,909
Cardiovascular System 10 | 15,192
Respiratory system 10 | 16,393

Target Family

Non-IDG 9 | 12,091
Kinase 2 | 634

GO Function

platelet-derived growth factor... 11 | 11
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Collagen alpha-1(VI) chain COL6A1 Tbio Non-IDG -2.03348 104.7 204
Collagen alpha-1(IV) chain COL4A1 Tbio Non-IDG -2.28595 186.9 391
Platelet-derived growth factor subunit A PDGFA Tchem Non-IDG -2.74845 537.8 341
Collagen alpha-1(III) chain COL3A1 Tbio Non-IDG -2.58251 354.8 439
Collagen alpha-1(I) chain COL1A1 Tbio Non-IDG -2.98303 874.8 508
Collagen alpha-1(V) chain COL5A1 Tbio Non-IDG -2.07285 114.2 274
Platelet-derived growth factor receptor alpha PDGFRA Tclin Kinase -2.95012 809.9 1423
Collagen alpha-1(II) chain COL2A1 Tbio Non-IDG -2.89229 724.4 424
Platelet-derived growth factor subunit B PDGFB Tchem Non-IDG -3.27151 1795.5 434
Collagen alpha-2(I) chain COL1A2 Tbio Non-IDG -2.64284 404.0 258