Development Level

Tclin 6 | 613

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

cardiovascular system phenotyp... 1 | 36
decreased heart rate variabili... 1 | 13

Disease

Carcinoma 6 | 11,493
Eaton-Lambert syndrome 6 | 40
Multiple Sclerosis 6 | 540
Kidney cancer 3 | 2,613
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
lung cancer 3 | 4,740
osteosarcoma 3 | 7,950
psoriasis 3 | 6,694
Astrocytoma, Pilocytic 2 | 3,081
Congenital myasthenic syndrome 5 2 | 11
Liver cancer 2 | 604
Long QT syndrome 2 | 39
Schizophrenia 2 | 1,160
adult high grade glioma 2 | 3,801
atypical teratoid / rhabdoid tumor 2 | 5,112
lung carcinoma 2 | 2,843
ovarian cancer 2 | 8,520
Acquired metabolic disease 1 | 336
Acute contagious conjunctivitis 1 | 7
Adducted thumb 1 | 22
Adrenoleukodystrophy 1 | 29
Aortic root dilatation 1 | 11
Arrhythmias, Cardiac 1 | 19
Atrial Fibrillation 1 | 124
Atrioventricular block 1 | 35
Background diabetic retinopathy 1 | 3
Breast Neoplasms 1 | 445
Broad hallux 1 | 29
Broad thumbs 1 | 28
Brugada syndrome 1 | 29
Bushy eyebrows 1 | 49
Campylobacteriosis 1 | 11
Cardiac Arrhythmia 1 | 103
Cardiac arrest 1 | 36
Cardiomyopathies 1 | 110
Cardiomyopathy 1 | 116
Cardioversion of Atrial Fibrillation 1 | 9
Catecholaminergic polymorphic ventricular tachycardia 1 | 12
Cell Transformation, Neoplastic 1 | 97
Coarse facial features 1 | 108
Colonic Neoplasms 1 | 142
Concave bridge of nose 1 | 195
Depressed nasal root/bridge 1 | 195
Dilated cardiomyopathy 1D 1 | 3
Downturned corners of mouth 1 | 48
Exudative vitreoretinopathy 1 | 15
Familial atrial fibrillation 1 | 23
Fibromatosis, Gingival 1 | 8
Flat forehead 1 | 5
Full lower lip 1 | 64
Heart conduction disease 1 | 83
Hepatitis 1 | 67
Hepatitis B 1 | 108
Hereditary gingival fibromatosis 1 | 8
Hirsutism 1 | 47
Hyperextensible digits 1 | 7
Hypokalemia 1 | 52
Idiopathic gingival hyperplasia 1 | 8
Infantile onset 1 | 238
Late tooth eruption 1 | 61
Life-Threatening Ventricular Tachycardia 1 | 15
Long QT syndrome 1 1 | 20
Long Qt Syndrome 2 1 | 5
Long philtrum 1 | 137
Mammary Neoplasms 1 | 425
Melanoma 1 | 711
Micronychia (disorder) 1 | 24
Muscular atrophy 1 | 71
Myopathic facies 1 | 13
Myopia 1 | 176
Nasal bridge wide 1 | 236
Neoplasms 1 | 63
Neoplastic Cell Transformation 1 | 89
Nonorganic psychosis 1 | 84
Osteoporosis 1 | 363
Palpitations 1 | 18
Progressive mental retardation 1 | 37
Prolonged QT interval 1 | 15
Prominent lower lip 1 | 64
Psychotic Disorders 1 | 151
Romano-Ward Syndrome 1 | 12
Severe mental retardation (I.Q. 20-34) 1 | 99
Short QT Syndrome 1 1 | 4
Short QT syndrome 1 | 12
Short distal phalanges 1 | 50
Shortened QT interval 1 | 5
Skin cancer 1 | 469
Spina bifida occulta 1 | 19
Sudden Cardiac Death 1 | 29
Sudden infant death syndrome 1 | 32
Syncope 1 | 22
Synophrys 1 | 40
Thickened facial skin with coarse facial features 1 | 108
Timothy syndrome 1 | 11
Torsades de Pointes 1 | 8
Ventricular Fibrillation 1 | 17
Wide nose 1 | 35
glioblastoma multiforme 1 | 142
tuberculosis and treatment for 3 months 1 | 179

Tissue

Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Digestive Tract 5 | 17,369
Liver and Pancreas 5 | 16,750
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678
Blood and immune system 4 | 16,909
Cardiovascular System 3 | 15,192
Respiratory system 3 | 16,393

Target Family

Ion Channel 6 | 344

GO Function

phosphorelay sensor kinase act... 6 | 6
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium voltage-gated channel subfamily H member 3 KCNH3 Tclin Ion Channel -1.07866 11.8 67
Potassium voltage-gated channel subfamily H member 5 KCNH5 Tclin Ion Channel -1.20155 17.8 40
Potassium voltage-gated channel subfamily H member 2 KCNH2 Tclin Ion Channel -3.22575 1653.9 243
Potassium voltage-gated channel subfamily H member 4 KCNH4 Tclin Ion Channel -1.41269 24.4 78
Potassium voltage-gated channel subfamily H member 1 KCNH1 Tclin Ion Channel -2.86111 714.2 150
Potassium voltage-gated channel subfamily H member 8 KCNH8 Tclin Ion Channel -0.66110 4.85 64